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Submissions from 2021

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Mast Cell Involvement in Fibrosis in Chronic Graft-versus-Host Disease, Ethan Strattan and Gerhard Carl Hildebrandt

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An Ensemble of the iCluster Method to Analyze Longitudinal lncRNA Expression Data for Psoriasis Patients, Suyan Tian and Chi Wang

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Gene Expression Barcode Values Reveal a Potential Link between Parkinson's Disease and Gastric Cancer, Suyan Tian, Shishun Zhao, Mingbo Tang, and Chi Wang

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Genomic Data from NSCLC Tumors Reveals Correlation between SHP-2 Activity and PD-L1 Expression and Suggests Synergy in Combining SHP-2 and PD-1/PD-L1 Inhibitors, Keller J. Toral, Mark A. Wuenschel, and Esther P. Black

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Access to and Use of Technology for Health: Comparisons Between Appalachian Kentuckians and the General U.S. Population, Robin C. Vanderpool, Lindsay R. Stradtman, Anna Gaysynsky, Quan Chen, Meghan Johnson, and Bin Huang

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Apolipoprotein E Genotype-Dependent Nutrigenetic Effects to Prebiotic Inulin for Modulating Systemic Metabolism and Neuroprotection in Mice via Gut-Brain Axis, Lucille M. Yanckello, Jared D. Hoffman, Ya-Hsuan Chang, Penghui Lin, Geetika Nehra, George Chlipala, Scott D. McCulloch, Tyler C. Hammond, Andrew T. Yackzan, Andrew N. Lane, Stefan J. Green, Anika M. S. Hartz, and Ai-Ling Lin

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Inhibition of Bruton Tyrosine Kinase Reduces Neuroimmune Cascade and Promotes Recovery after Spinal Cord Injury, Chen Guang Yu, Vimala Bondada, Hina Iqbal, Kate L. Moore, John C. Gensel, Subbarao Bondada, and James W. Geddes

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Mechanisms of Smoothened Regulation in Hedgehog Signaling, Jie Zhang, Zulong Liu, and Jianhang Jia

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Co-Targeting Plk1 and DNMT3a in Advanced Prostate Cancer, Zhuangzhuang Zhang, Lijun Cheng, Qiongsi Zhang, Yifan Kong, Daheng He, Kunyu Li, Matthew Rea, Jianlin Wang, Ruixin Wang, Jinghui Liu, Zhiguo Li, Chongli Yuan, Enze Liu, Yvonne N. Fondufe-Mittendorf, Lang Li, Tao Han, Chi Wang, and Xiaoqi Liu

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CD151 Drives Cancer Progression Depending on Integrin α3β1 through EGFR Signaling in Non-Small Cell Lung Cancer, Jianjie Zhu, Tingting Cai, Jieqi Zhou, Wenwen Du, Yuanyuan Zeng, Ting Liu, Yulong Fu, Yue Li, Qian Qian, Xiuwei H. Yang, Qinglin Li, Jian-an Huang, and Zeyi Liu

Submissions from 2020

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Spatial Profiling of Gangliosides in Mouse Brain by Mass Spectrometry Imaging, Douglas A. Andres, Lyndsay E. A. Young, Matthew S. Gentry, and Ramon C. Sun

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Gynecologic Large Cell Neuroendocrine Carcinoma: A Review, Grant Burkeen, Aman Chauhan, Rohitashva Agrawal, Riva Raiker, Jill M. Kolesar, Lowell B. Anthony, B. Mark Evers, and Susanne Arnold

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Deep Learning vs. Atlas-Based Models for Fast Auto-Segmentation of the Masticatory Muscles on Head and Neck CT Images, Wen Chen, Yimin Li, Brandon A. Dyer, Xue Feng, Shyam Rao, Stanley H. Benedict, Quan Chen, and Yi Rong

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Clinical Application of Oncolytic Viruses: A Systematic Review, Mary Cook and Aman Chauhan

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Tackle Epithelial-Mesenchymal Transition with Epigenetic Drugs in Cancer, Bo Dong, Zhaoping Qiu, and Yadi Wu

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Spermine Synthase and MYC Cooperate to Maintain Colorectal Cancer Cell Survival by Repressing Bim Expression, Yubin Guo, Qing Ye, Pan Deng, Yanan Cao, Daheng He, Zhaohe Zhou, Chi Wang, Yekaterina Y. Zaytseva, Charles E. Schwartz, Eun Young Lee, B. Mark Evers, Andrew J. Morris, Side Liu, and Qing-Bai She

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Barn-Raising on the Digital Frontier: The L.A.U.N.C.H. Collaborative, Bradford W. Hesse, David Ahern, Michele Ellison, Eliah Aronoff-Spencer, Robin C. Vanderpool, Karen Onyeije, Michael C. Gibbons, Timothy W. Mullett, Ming-Yuan Chih, Victoria Attencio, Grant Patterson, Jessica Boten, Christopher Hartshorn, Ben Bartolome, Katie Gorscak, Melanie McComsey, Alexandra Hubenko, Bin Huang, Corey Baker, and Don Norman

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GOcats: A Tool for Categorizing Gene Ontology into Subgraphs of User-Defined Concepts, Eugene Waverly Hinderer III and Hunter N. B. Moseley

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A Brief Educational Intervention Enhances Basic Cancer Literacy among Kentucky Middle and High School Students, Lauren Hudson, Kerrigan M. Samons, Haley E. Dicken, Chris Prichard, L. Todd Weiss, Jean Edward, Robin C. Vanderpool, and Nathan L. Vanderford

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Atom Identifiers Generated by a Neighborhood-Specific Graph Coloring Method Enable Compound Harmonization across Metabolic Databases, Huan Jin, Joshua M. Mitchell, and Hunter N. B. Moseley

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Immune-Mediated Genetic Pathways Resulting in Pulmonary Function Impairment Increase Lung Cancer Susceptibility, Linda Kachuri, Mattias Johansson, Sara R. Rashkin, Rebecca E. Graff, Yohan Bossé, Venkata Manem, Neil E. Caporaso, Maria Teresa Landi, David C. Christiani, Paolo Vineis, Geoffrey Liu, Ghislaine Scelo, David Zaridze, Sanjay S Shete, Demetrius Albanes, Melinda C. Aldrich, Adonina Tardón, Gad Rennert, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, Heike Bickeböller, John K. Field, Michael P Davies, M. Dawn Teare, Lambertus A. Kiemeney, Stig E. Bojesen, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Loïc Le Marchand, Iona Cheng, Matthew B. Schabath, Eric J. Duell, Angeline S. Andrew, Jonas Manjer, Philip Lazarus, Susanne M. Arnold, James D. McKay, Nima C. Emami, Matthew T. Warkentin, Yonathan Brhane, Ma'en Obeidat, Richard M. Martin, Caroline Relton, George Davey Smith, Philip C. Haycock, Christopher I. Amos, Paul Brennan, John S. Witte, and Rayjean J. Hung

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EGFR Testing and Erlotinib Use in Non-Small Cell Lung Cancer Patients in Kentucky, Kara L. Larson, Bin Huang, Quan Chen, Thomas C. Tucker, Marissa Schuh, Susanne M. Arnold, and Jill M. Kolesar

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Genome-Wide DNA Methylation Profiling in Human Breast Tissue by Illumina TruSeq Methyl Capture EPIC Sequencing and Infinium MethylationEPIC Beadchip Microarray, Nan Lin, Jinpeng Liu, James Castle, Jun Wan, Aditi Shendre, Yunlong Liu, Chi Wang, and Chunyan He

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A New Efficient Method to Detect Genetic Interactions for Lung Cancer GWAS, Jennifer Luyapan, Xuemei Ji, Siting Li, Xiangjun Xiao, Dakai Zhu, Eric J. Duell, David C. Christiani, Matthew B. Schabath, Susanne M. Arnold, Shanbeh Zienolddiny, Hans Brunnström, Olle Melander, Mark D. Thornquist, Todd A. MacKenzie, Christopher I. Amos, and Jiang Gui

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The SRG Rat, a Sprague-Dawley Rag2/Il2rg Double-Knockout Validated for Human Tumor Oncology Studies, Fallon K. Noto, Jaya Sangodkar, Bisoye Towobola Adedeji, Sam Moody, Christopher B. McClain, Ming Tong, Eric Ostertag, Jack Crawford, Xiaohua Gao, Lauren Hurst, Caitlin M. O'Connor, Erika N. Hanson, Sudeh Izadmehr, Rita Tohmé, Jyothsna Narla, Kristin LeSueur, Kajari Bhattacharya, Amit Rupani, Marwan K. Tayeh, Jeffrey W. Innis, Matthew D. Galsky, B. Mark Evers, Analisa DiFeo, Goutham Narla, and Tseten Y. Jamling