Submissions from 2024
Relative Adrenal Insufficiency Is a Risk Factor for Pediatric Sepsis: A Proof-of-Concept Study, Dan Hao, Ling Guo, Qian Wang, Misa Ito, Bin Huang, Chieko Mineo, Philip W. Shaul, and Xiang-An Li
CD8+ T cell metabolic flexibility elicited by CD28-ARS2 axis- driven alternative splicing of PKM supports antitumor immunity, G. Aaron Holling, Colin A. Chavel, Anand P. Sharda, Mackenzie M. Lieberman, Caitlin M. James, Shivana M. Lightman, Jason H. Tong, Guanxi Qiao, Tiffany R. Emmons, Thejaswini Giridharan, Shengqi Hou, Andrew M. Intlekofer, Richard M. Higashi, Teresa W. M. Fan, Andrew N. Lane, Kevin H. Eng, Brahm H. Segal, Elizabeth A. Repasky, Kevin P. Lee, and Scott H. Olejniczak
Predicting the Association of Metabolites with Both Pathway Categories and Individual Pathways, Erik D. Huckvale and Hunter Moseley
Predicting the Pathway Involvement of All Pathway and Associated Compound Entries Defined in the Kyoto Encyclopedia of Genes and Genomes, Erik D. Huckvale and Hunter Moseley
A cautionary tale about properly vetting datasets used in supervised learning predicting metabolic pathway involvement, Erik D. Huckvale and Hunter N. B. Moseley
Predicting the Pathway Involvement of Metabolites Based on Combined Metabolite and Pathway Features, Erik D. Huckvale and Hunter N. B. Moseley
Feasibility and Clinical Utility of Reporting Hereditary Cancer Predisposition Pathogenic Variants Identified in Research Germline Sequencing: A Prospective Interventional Study, Megan L. Hutchcraft, Shulin Zhang, Nan Lin, Justine C. Pickarski, Elizabeth Belcher, Sainan Wei, Therese J. Bocklage, Rachel W. Miller, John L. Villano, Michael J. Cavnar, Joseph Kim, Susanne M. Arnold, Frederick R. Ueland, and Jill M. Kolesar
Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine., Anmi Jose, Pallavi Kulkarni, Jaya Thilakan, Murali Munisamy, Anvita Gupta Malhotra, Jitendra Singh, Ashok Kumar, Vivek M. Rangnekar, Neha Arya, and Mahadev Rao
Putting biomonitors to work: native moss as a screening tool for solid waste incineration, Sarah Jovan, Eleonore Jacobson, Jason M. Unrine, Nasser Jalili‑Jahani, and Bruce McCune
Upregulation of Fatty Acid Synthase Increases Activity of β-Catenin and Expression of NOTUM to Enhance Stem-like Properties of Colorectal Cancer Cells, Courtney O. Kelson, Josiane Weber Tessmann, Mariah E. Geisen, Daheng He, Chi Wang, Tianyan Gao, B. Mark Evers, and Yekaterina Y. Zaytseva
Altered lipid metabolism in APC-driven colorectal cancer: the potential for therapeutic intervention, Courtney O. Kelson and Yekaterina Y. Zaytseva
Extended conformations of bifurcating electron transfer flavoprotein constitute up to half the population, possibly mediating conformational change, Sharique A. Khan, Alan Hicks, Wellington C. Leite, James Byrnes, Biswajit Gorai, Maria-Andrea Mroginski, Hugh O'Neill, and Anne-Francis Miller
Structure, dynamics, and redox reactivity of an all-purpose flavodoxin, Sharique Khan, Ahmadullah Ansari, Monica Brachi, Debarati Das, Wassim El Housseini, Shelley Minteer, and Anne-Francis Miller
Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats, Shailesh N. Khatri, Hanaa Ulangkaya, Erin E. Maher, Safiyah M. Sadek, Mei Hong, Andrea M. Woodcox, William W. Stoops, and Cassandra D. Gipson
Physicochemical Property Effects on Immune Modulating Polymeric Nanoparticles: Potential Applications in Spinal Cord Injury, Daniel J. Kolpek, Jaechang Kim, Hisham Mohammed, John C. Gensel, and Jonghyuck Park
Single-cell analysis identifies PLK1 as a driver of immunosuppressive tumor microenvironment in LUAD, Yifan Kong, Chaohao Li, Jinpeng Liu, and Sai Wu
Challenges of Spatially Resolved Metabolism in Cancer Research, Andrew N. Lane, Richard M. Higashi, and Teresa W-M Fan
Biliverdin Reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β, Chiara Lanzillotta, Antonella Tramutola, Simona Lanzillotta, Viviana Greco, Sara Pagnotta, Caterina Sanchini, Silvia Di Angelantonio, Elena Forte, Serena Rinaldo, Alessio Paone, Francesca Cutruzzolà, Flavia Agata Cimini, Ilaria Barchetta, Maria Gisella Cavallo, Andrea Urbani, D. Allan Butterfield, Fabio Di Domenico, Bindu D. Paul, Marzia Perluigi, and Joao M.N. Duarte
Assessing the feasibility of a multimodal liquid biopsy for the diagnosis of HPV-associated oropharyngeal squamous cell carcinoma., James S. Lewis, Saskia Naegele, Vasileios Efthymiou, Mitra Mehrad, Kim A. Ely, Tim Waterboer, Krystle A. Lang Kuhs, Seth J. Davis, Kelsey Richard, Dipon Das, and Daniel L. Faden
miR-27a-3p regulates intestinal cell proliferation and differentiation through Wnt/β-catenin signalling, Chang Li, Yuning Zhou, Yinping Jiang, Zhijie Yin, Heidi L. Weiss, Qingding Wang, and B. Mark Evers
Executing plans to enhance diversity across cancer centers in the United States: opportunities and challenges, Christopher I. Li, Sherise Chantell Rogers, Carol J. Bult, Carmen E. Guerra, Angela Talton, Lovoria B. Williams, and Wendy Law
Neurotensin accelerates atherosclerosis and increases circulating levels of short-chain and saturated triglycerides, Jing Li, Liping Yang, Jun Song, Baoxiang Yan, Andrew J. Morris, Hunter Moseley, Robert M. Flight, Chi Wang, Jinpeng Liu, Heidi L. Weiss, Edward F. Morris, Ilyes Abdelhamid, Mathias J. Gerl, Olle Melander, Susan Smyth, and B. Mark Evers
Novel psychoplastogen DM506 reduces cue-induced heroin-seeking and inhibits tonic GABA currents in the Prelimbic Cortex, Kassandra Looschen, Shailesh N. Khatri, Malabika Maulik, Colin Salisbury, Alaina F. Carman, Katilyn Corriveau, Colton Smith, Dina Manetti, Maria Novella Romanelli, Hugo R. Arias, Cassandra D. Gipson, and Swarup Mitra
Cold-Inducible RNA Binding Protein Impedes Breast Tumor Growth in the PyMT Murine Model for Breast Cancer, Daniel A. Lujan, Joey L. Ochoa, Ellen J. Beswick, Tamara A. Howard, Helen J. Hathaway, Nora I. Perrone-Bizzozero, and Rebecca S. Hartley
Association Between Obesity and Risk of Total and Obesity-Related Cancer in People With Incident Cardiovascular Disease., Sarah Malik, Avirup Guha, Xiaoling Wang, Neal L. Weintraub, Ryan Harris, Biplab Datta, Justin Moore, Priyanshu Nain, Sagar A. Patel, Steven Coughlin, Elizabeth Polter, Anna Prizment, Anne Blaes, Roberta Florido, Shelby Kutty, Alvaro Alonso, Corinne E. Joshu, and Elizabeth A. Platz
