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Submissions from 2024

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Clinical and Genomic Features of Patients with Renal Cell Carcinoma and Advanced Chronic Kidney Disease: Analysis of a Multi-Institutional Database., Corbin J. Eule, Junxiao Hu, Dale Hedges, Alkesh Jani, Thomas Pshak, Brandon J. Manley, Alejandro Sanchez, Robert Dreicer, Zin W. Myint, Yousef Zakharia, and Elaine T. Lam

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Non-transcriptional IRF7 interacts with NF-κB to inhibit viral inflammation, Shumin Fan, Sonam Popli, Sukanya Chakravarty, Ritu Chakravarty, and Saurabh Chattopadhyay

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In-clinic Versus Online Recruitment of Women With a History of Cervical Intraepithelial Neoplasia or Cervical Cancer to a Smoking Cessation Trial: A Post hoc Comparison of Participant Characteristics, Study Retention, and Cessation Outcomes., Bethany Shorey Fennell, Sarah R. Jones, Steven K. Sutton, Charles E. Hoogland, Cherell Cottrell-Daniels, David W. Wetter, Ya-Chen Tina Shih, Vani N. Simmons, Yesenia P. Stephens, Damon J. Vidrine, and Jennifer I. Vidrine

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Impact of gut microbiota and its metabolites on immunometabolism in colorectal cancer, Madison Flory, Paloma Bravo, and Asfaqul Alam

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An Intelligent Search & Retrieval System (IRIS) and Clinical and Research Repository for Decision Support Based on Machine Learning and Joint Kernel-based Supervised Hashing., David J Foran, Wenjin Chen, Tahsin Kurc, Rajarshi Gupta, Jakub Roman Kaczmarzyk, Luke Austin Torre-Healy, Erich Bremer, Samuel Ajjarapu, Nhan Do, Gerald Harris, Antoinette Stroup, Eric B. Durbin, and Joel H Saltz

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Retinoic Acid-Mediated Inhibition of Mouse Coronavirus Replication Is Dependent on IRF3 and CaMKK, Justin H. Franco, Ryan A. Harris, William G. Ryan, Roger Travis Taylor, Robert E. McCullumsmith, Saurabh Chattopadhyay, and Zhixing K. Pan

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Effect of mitochondrial oxidative stress on regulatory T cell manufacturing for clinical application in transplantation: Results from a pilot study, Roberto Gedaly, Gabriel Orozco, Lillie J. Lewis, Deepa Valvi, Fanny Chapelin, Aman Khurana, Giovanna E. Hidalgo, Aaron Shmookler, Aashutosh Tripathi, Cuiping Zhang, Joseph B. Zwischenberger, and Francesc Marti

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Population-level incidence of human papillomavirus–positive oropharyngeal, cervical, and anal cancers, by smoking status, Sameer V. Gopalani, Mona Saraiya, Bin Huang, Thomas Tucker, Jacqueline M. Mix, and Anil K. Chaturvedi

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Inhibition of Carbohydrate Metabolism Potentiated by the Therapeutic Effects of Oxidative Phosphorylation Inhibitors in Colon Cancer Cells, Lichao Guo, Baochen Zhang, Wen Zhang, Yanqi Xie, Xi Chen, Xueke Sun, David S. Watt, Chunming Liu, H. Peter Spielmann, and Xifu Liu

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Relative Adrenal Insufficiency Is a Risk Factor for Pediatric Sepsis: A Proof-of-Concept Study, Dan Hao, Ling Guo, Qian Wang, Misa Ito, Bin Huang, Chieko Mineo, Philip W. Shaul, and Xiang-An Li

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CD8+ T cell metabolic flexibility elicited by CD28-ARS2 axis- driven alternative splicing of PKM supports antitumor immunity, G. Aaron Holling, Colin A. Chavel, Anand P. Sharda, Mackenzie M. Lieberman, Caitlin M. James, Shivana M. Lightman, Jason H. Tong, Guanxi Qiao, Tiffany R. Emmons, Thejaswini Giridharan, Shengqi Hou, Andrew M. Intlekofer, Richard M. Higashi, Teresa W. M. Fan, Andrew N. Lane, Kevin H. Eng, Brahm H. Segal, Elizabeth A. Repasky, Kevin P. Lee, and Scott H. Olejniczak

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Predicting the Association of Metabolites with Both Pathway Categories and Individual Pathways, Erik D. Huckvale and Hunter Moseley

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Predicting the Pathway Involvement of All Pathway and Associated Compound Entries Defined in the Kyoto Encyclopedia of Genes and Genomes, Erik D. Huckvale and Hunter Moseley

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A cautionary tale about properly vetting datasets used in supervised learning predicting metabolic pathway involvement, Erik D. Huckvale and Hunter N. B. Moseley

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Predicting the Pathway Involvement of Metabolites Based on Combined Metabolite and Pathway Features, Erik D. Huckvale and Hunter N. B. Moseley

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Feasibility and Clinical Utility of Reporting Hereditary Cancer Predisposition Pathogenic Variants Identified in Research Germline Sequencing: A Prospective Interventional Study, Megan L. Hutchcraft, Shulin Zhang, Nan Lin, Justine C. Pickarski, Elizabeth Belcher, Sainan Wei, Therese J. Bocklage, Rachel W. Miller, John L. Villano, Michael J. Cavnar, Joseph Kim, Susanne M. Arnold, Frederick R. Ueland, and Jill M. Kolesar

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Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine., Anmi Jose, Pallavi Kulkarni, Jaya Thilakan, Murali Munisamy, Anvita Gupta Malhotra, Jitendra Singh, Ashok Kumar, Vivek M. Rangnekar, Neha Arya, and Mahadev Rao

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Putting biomonitors to work: native moss as a screening tool for solid waste incineration, Sarah Jovan, Eleonore Jacobson, Jason M. Unrine, Nasser Jalili‑Jahani, and Bruce McCune

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Upregulation of Fatty Acid Synthase Increases Activity of β-Catenin and Expression of NOTUM to Enhance Stem-like Properties of Colorectal Cancer Cells, Courtney O. Kelson, Josiane Weber Tessmann, Mariah E. Geisen, Daheng He, Chi Wang, Tianyan Gao, B. Mark Evers, and Yekaterina Y. Zaytseva

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Altered lipid metabolism in APC-driven colorectal cancer: the potential for therapeutic intervention, Courtney O. Kelson and Yekaterina Y. Zaytseva

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Extended conformations of bifurcating electron transfer flavoprotein constitute up to half the population, possibly mediating conformational change, Sharique A. Khan, Alan Hicks, Wellington C. Leite, James Byrnes, Biswajit Gorai, Maria-Andrea Mroginski, Hugh O'Neill, and Anne-Francis Miller

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Structure, dynamics, and redox reactivity of an all-purpose flavodoxin, Sharique Khan, Ahmadullah Ansari, Monica Brachi, Debarati Das, Wassim El Housseini, Shelley Minteer, and Anne-Francis Miller

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Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats, Shailesh N. Khatri, Hanaa Ulangkaya, Erin E. Maher, Safiyah M. Sadek, Mei Hong, Andrea M. Woodcox, William W. Stoops, and Cassandra D. Gipson

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Physicochemical Property Effects on Immune Modulating Polymeric Nanoparticles: Potential Applications in Spinal Cord Injury, Daniel J. Kolpek, Jaechang Kim, Hisham Mohammed, John C. Gensel, and Jonghyuck Park

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Single-cell analysis identifies PLK1 as a driver of immunosuppressive tumor microenvironment in LUAD, Yifan Kong, Chaohao Li, Jinpeng Liu, and Sai Wu