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Submissions from 2024

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Zebrafish drug screening identifies Erlotinib as an inhibitor of Wnt/ β-catenin signaling and self-renewal in T-cell acute lymphoblastic leukemia, Majd A. Al-Hamaly, Anna H. Cox, Meghan G. Haney, Wen Zhang, Emma C. Arvin, Shilpa Sampathi, Mary Wimsett, Chunming Liu, and Jessica S. Blackburn

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Shared genomic segments analysis identifies MHC class I and class III molecules as genetic risk factors for juvenile idiopathic arthritis, Cecile N. Avery, Nicole D. Russell, Cody J. Steely, Aimee O. Hersh, John F. Bohnsack, Sampath Prahalad, and Lynn B. Jorde

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14-3-3ζ suppresses RANKL signaling by destabilizing TRAF6, R. Ayyasamy, S. Fan, P. Czernik, B. Lecka-Czernik, S. Chattopadhyay, and R. Chakravarti

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FOXS1 is increased in liver fibrosis and regulates TGFβ responsiveness and proliferation pathways in human hepatic stellate cells, Evelyn A. Bates, Zachary A. Kipp, Wang-Hsin Lee, Genesee J. Martinez, Lauren Weaver, Kathryn N. Becker, Sally Pauss, Justin F. Creeden, Garrett B. Anspach, Robert N. Helsley, Mei Xu, Maria E. C. Bruno, Marlene E. Starr, and Terry D. Hinds Jr.

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Sedimentation of large, soluble proteins up to 140 kDa for 1H-detected MAS NMR and 13C DNP NMR – practical aspects, Dallas Bell, Florian Lindemann, Lisa Gerland, Hanna Aucharova, Alexander Klein, Daniel Friedrich, Matthias Hiller, Kristof Grohe, Tobias Meier, Barth van Rossum, Anne Diehl, Jon Hughes, Leonard J. Mueller, Rasmus Linser, Anne-Frances Miller, and Hartmut Oschkinat

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Discussions of Cancer Survivorship Care Needs: Are There Rural Versus Urban Inequities?, Tyrone F. Borders and Lindsey R. Hammerslag

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A framework and process for community‑engaged, mixed‑methods cancer needs assessments, Todd Burus, Jessica R. Thompson, Caree R. McAfee, Lovoria B. Williams, Jennifer R. Knight, Bin Huang, Sarojini Kanotra, Natalie P. Wilhite, Elaine Russell, Melinda Rogers, Connie L. Sorrell, Christine Stroebel, Rachael King, and Pamela C. Hull

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Travel-Time Disparities in Access to Proton Beam Therapy for Cancer Treatment, Todd Burus, Alexander D. VanHelene, Michael K. Rooney, Krystle A. Lang Kuhs, W. Jay Christian, Christopher McNair, Sanjay Mishra, Arnold C. Paulino, Grace L. Smith, Steven J. Frank, and Jeremy L. Warner

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Smoking Cessation by Cancer Treatment Status Among Cervical Cancer Survivors, Cherell Cottrell-Daniels, Charles E. Hoogland, Bethany Shorey Fennell, Vani N. Simmons, Damon J. Vidrine, and Jennifer I. Vidrine

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Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies, Saeed Daneshmandi, Jee Eun Choi, Qi Yan, Cameron R. MacDonald, Manu Pandey, Mounika Goruganthu, Nathan Roberts, Prashant K. Singh, Richard M. Higashi, Andrew N. Lane, Teresa W-M Fan, Jianmin Wang, Philip L. McCarthy, Elizabeth A. Repasky, and Hemn Mohammadpour

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Profiling the molecular and clinical landscape of glioblastoma utilizing the Oncology Research Information Exchange Network brain cancer database, Alexandra N. Demetriou, Frances Chow, David W. Craig, Michelle G. Webb, D. Ryan Ormond, James Battiste, Arnab Chakravarti, Howard Colman, John L. Villano, Bryan P. Schneider, James K. C. Liu, Michelle L. Churchman, and Gabriel Zada

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Overexpression of Fatty Acid Synthase Upregulates Glutamine–Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth, James Drury, Mariah E. Geisen, Josiane Weber Tessmann, Piotr G. Rychahou, and Courtney O. Kelson

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Financial-legal navigation reduces financial toxicity of pediatric, adolescent, and young adult cancers, Jean Edward, Kimberly D. Northrip, Mary Kay Rayens, Andrea Welker, Rachel O'Farrel, Jennifer Knuf, Haafsah Fariduddin, Julia Costich, and John A. D'Orazio

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Non-transcriptional IRF7 interacts with NF-κB to inhibit viral inflammation, Shumin Fan, Sonam Popli, Sukanya Chakravarty, Ritu Chakravarty, and Saurabh Chattopadhyay

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Retinoic Acid-Mediated Inhibition of Mouse Coronavirus Replication Is Dependent on IRF3 and CaMKK, Justin H. Franco, Ryan A. Harris, William G. Ryan, Roger Travis Taylor, Robert E. McCullumsmith, Saurabh Chattopadhyay, and Zhixing K. Pan

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A cautionary tale about properly vetting datasets used in supervised learning predicting metabolic pathway involvement, Erik D. Huckvale and Hunter N. B. Moseley

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Predicting the Pathway Involvement of Metabolites Based on Combined Metabolite and Pathway Features, Erik D. Huckvale and Hunter N. B. Moseley

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Feasibility and Clinical Utility of Reporting Hereditary Cancer Predisposition Pathogenic Variants Identified in Research Germline Sequencing: A Prospective Interventional Study, Megan L. Hutchcraft, Shulin Zhang, Nan Lin, Justine C. Pickarski, Elizabeth Belcher, Sainan Wei, Therese J. Bocklage, Rachel W. Miller, John L. Villano, Michael J. Cavnar, Joseph Kim, Susanne M. Arnold, Frederick R. Ueland, and Jill M. Kolesar

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Altered lipid metabolism in APC-driven colorectal cancer: the potential for therapeutic intervention, Courtney O. Kelson and Yekaterina Y. Zaytseva

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Structure, dynamics, and redox reactivity of an all-purpose flavodoxin, Sharique Khan, Ahmadullah Ansari, Monica Brachi, Debarati Das, Wassim El Housseini, Shelley Minteer, and Anne-Francis Miller

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Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats, Shailesh N. Khatri, Hanaa Ulangkaya, Erin E. Maher, Safiyah M. Sadek, Mei Hong, Andrea M. Woodcox, William W. Stoops, and Cassandra D. Gipson

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Challenges of Spatially Resolved Metabolism in Cancer Research, Andrew N. Lane, Richard M. Higashi, and Teresa W-M Fan

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Neurotensin accelerates atherosclerosis and increases circulating levels of short-chain and saturated triglycerides, Jing Li, Liping Yang, Jun Song, Baoxiang Yan, Andrew J. Morris, Hunter Moseley, Robert M. Flight, Chi Wang, Jinpeng Liu, Heidi L. Weiss, Edward F. Morris, Ilyes Abdelhamid, Mathias J. Gerl, Olle Melander, Susan Smyth, and B. Mark Evers

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A Novel Protozoa Parasite-Derived Protein Adjuvant Is Effective in Immunization with Cancer Cells to Activate the Cancer-Specific Protective Immunity and Inhibit the Cancer Growth in a Murine Model of Colorectal Cancer, Rajesh Mani, Chloe G. Martin, Kanal E. Balu, Qingding Wang, Piotr G. Rychahou, Tadahide Izumi, B. Mark Evers, and Yasuhiro Suzuki

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The hagfish genome and the evolution of vertebrates, Ferdinand Marlétaz, Nataliya Timoshevskaya, Vladimir A. Timoshevskiy, Elise Parey, Oleg Simakov, Daria Gavriouchkina, Masakazu Suzuki, Kaoru Kubokawa, Sydney Brenner, Jeramiah James Smith, and Daniel S. Rokhsar