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Submissions from 2026

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Understanding the role of age and U.S. acculturation factors on the relationship between allostatic load and cancer mortality risk in Hispanic Americans, Jessica Amezcua, Valeria Miranda, Melissa Lopez-Pentecost, Jessica Y. Islam, Marlo M. Vernon, Kathleen O’Connor, and Justin Xavier Moore

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Cardioprotective Effects of 1,3 Butanediol in MASLD via Reversal of Cardiac Lipid Accumulation and Suppression of Cardiac Fibrosis, Olufunto O. Badmus, Landon D. Parrow, Karis E. McGowen, La Brenda Bell, Jennifer R. Greer, Marcela de Carvalho Cruz, Terry D. Hinds, and David E. Stec

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q Is a Heterotrimeric G-Protein Subunit That Directs the Selectivity of PPARγ-Induced Gene Pathways Toward Energy-Related Processes Rather than Adiposity, Evelyn A. Bates, Zachary A. Kipp, Wang Hsin Lee, Genesee J. Martinez, Sally N. Pauss, Philipp E. Scherer, and Terry D. Hinds

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Survival of Patients Diagnosed With Cancer During the COVID-19 Pandemic, Todd Burus, Haluk Damgacioglu, Bin Huang, Thomas C. Tucker, Ashish A. Deshmukh, and Krystle A. Lang Kuhs

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Geographic clusters of human papillomavirus-associated cancer incidence in the US, 2008–2022, Todd Burus, Krystle A. Lang Kuhs, Ashish A. Deshmukh, and Haluk Damgacioglu

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A Phase 1 Dose Escalation of Lapatinib and Paclitaxel in Recurrent Ovarian Cancer, Connie D. Cao, Joseph Robert McCorkle, Donglin Yan, Hoda Saghaeiannejad Esfahani, Rani Jayswal, Dava W. Piecoro, Ning Li, Lauren Baldwin, Rachel W. Miller, Christopher P. DeSimone, Charles S. Dietrich, Frederick R. Ueland, and Jill M. Kolesar

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Colon cancer in Appalachian Kentucky: Unique genetic, microbiome and obesity findings in a cohort comparison, Zeta Chow, Jinpeng Liu, Daheng He, Chi Wang, Tong Gan, Akila Mansour, Nuha Shaker, Caroline Dravillas, Rebecca Hoyd, Eric B. Durbin, Dana L. Napier, Tianyan Gao, Kurt Schaberg, Lyen Huang, Neli Ulrich, Erin Siegel, Stephen Edge, Linda Cook, Bodour Salhia, Michelle L. Churchman, Jill Kolesar, Daniel Spakowicz, B. Mark Evers, and Therese J. Bocklage

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Discrimination Distress and Current Combustible and Non-combustible Tobacco Product Use Among US Youth, 2023, Meman Diaby, Osayande Agbonlahor, Maggie K. Richardson, Joy L. Hart, Shyanika W. Rose, and Delvon T. Mattingly

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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS, Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, and Grant J. Jensen

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Characteristics of the Health-Associated Oral Microbiome in Young Nonhuman Primates, J. L. Ebersole and O. A. Gonzalez

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Mental Health Needs of Families of Patients in Intensive Care Units and the Role of Mobile Health: Survey Study, Anthony Faiola, Saira Soroya, Zhonglin Hao, and Reinhold Munker

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Information-Content-Informed Kendall-Tau Correlation Methodology, Robert M. Flight, Praneeth S. Bhatt, and Hunter N.B. Moseley

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Systemic Consequences of Chronic Ethanol Intake, Muni Swamy Ganjayi, Thomas A. Krauss, Gage E. Demster, Sehyung Park, Garrett B. Anspach, Sarah R. Anthony, Shaohua Wang, Michael Tranter, Robert N. Helsley, and Cory W. Baumann

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Association of Clinical Severity in Autism Spectrum Disorder with Biomolecules Involved in Lipid Metabolism, Inflammation and miRNAs, Maria Gevezova, Michael Maes, Iliana Pacheva, Nikolay Mehterov, Zdravko Ivanov, Elena Timova, Stefka Spassieva, Erhard Bieberich, Maria Kazakova, Ivan Ivanov, and Victoria Sarafian

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Osimertinib activates a TGF-β2-dependent secretory program that drives lung adenocarcinoma progression, Madhurima Ghosh, Chao Wu, Abhishek Kumar, Monique Nilsson, John V. Heymach, Weina Zhao, Jiang Yu, Xin Liu, Na Ding, Shike Wang, Guan Yu Xiao, Angelo Chen, Kate Grimley, William K. Russell, Chad J. Creighton, Xiaochao Tan, and Jonathan M. Kurie

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Hexavalent chromium promotes malignant transformation via enhanced translation of SUV39H1, Yiwei Gu, Yanan Cao, Qing Ye, Yujing Zhang, Zhishan Wang, Chengfeng Yang, Side Liu, and Qing-Bai She

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Developing a multidisciplinary pediatric cancer predisposition service at a mid-sized children’s hospital, Amanda M. Harrington and John August D'Orazio

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Mapping the Polar Neuro-Interactome of Garcinia mangostana Against the AD-PD-ALS Nexus, Rahni Hossain, Sirirat Surinkaew, Pradoldej Sompol, Nasmah K. Bastaki, Rifat Jafrin, Nazim Sekeroglu, and Jitbanjong Tangpong

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Chemical Structure Representation Standardization Is Needed to Generalize Metabolite-Pathway Involvement Prediction Across KEGG, Reactome, and MetaCyc Knowledgebases, Erik D. Huckvale and Hunter N.B. Moseley

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Alterations of Cerebral Extracellular Vesicle microRNA Profiling Potentially Disrupts Brain Homeostasis Following Myocardial Infarction, Md Monowarul Islam, Shouyi Liang, Lijun Sun, Guoku Hu, Neha Dhyani, Lie Gao, Tara L. Rudebush, Xue Xu, Jinpeng Liu, Irving H. Zucker, and Changhai Tian

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Targeting RSK2 reverses endocrine resistance in ER-positive breast cancer via inhibiting the c-Myc–ERBB4 signaling pathway, Ting Jiang, Shilong Jiang, Yueying Cheng, Xiaohui Yu, Zonglin Chen, Hang Li, Shijun Cao, Zhongyuan Xiang, Ruigang Zhao, Wenjun Yi, Jinming Yang, and Yan Cheng

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RNA-Micelles as Self-Assembling Structures for Efficient Co-Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis, Kai Jin, Piotr G. Rychahou, Daniel W. Binzel, B. Mark Evers, and Peixuan Guo

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Sex-specific adaptive immune responses in spinal cord injury, Reena Kumari and John C. Gensel

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Antioxidant Therapy Reverses Hepatotoxicity Induced by Microcystin-LR in a Cellular Model of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), Apurva Lad, Jason Kindle, Prajwal Hegde, Gabriel G. Kleer, Andrew L. Kleinhenz, Johnna A. Birbeck, Judy Westrick, Nicholas J. Peraino, Terry D. Hinds, Neeraja Purandare, Andrew M. Fribley, Steven T. Haller, and David J. Kennedy

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Oncology Clinicians’ Attitudes on Hormonal Therapy After Chemoradiotherapy for Cervical Cancer, Morgan S. Levy, Marilyn Huang, Charles S. Dietrich, and Denise Fabian