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Submissions from 2021

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Cellular Origins of EGFR-Driven Lung Cancer Cells Determine Sensitivity to Therapy, Fan Chen, Jinpeng Liu, Robert M. Flight, Kassandra J. Naughton, Alexsandr Lukyanchuk, Abigail R Edgin, Xiulong Song, Haikuo Zhang, Kwok-Kin Wong, Hunter N. B. Moseley, Chi Wang, and Christine F. Brainson

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PI3K/mTOR Dual Inhibitor PF-04691502 Is a Schedule-Dependent Radiosensitizer for Gastroenteropancreatic Neuroendocrine Tumors, Zeta Chow, Jeremy Johnson, Aman Chauhan, Tadahide Izumi, Michael Cavnar, Heidi L. Weiss, Courtney M. Townsend Jr., Lowell B. Anthony, Carrigan Wasilchenko, Matthew L. Melton, Jörg Schrader, B. Mark Evers, and Piotr G. Rychahou

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Understanding Parents' Views toward the Newly Enacted HPV Vaccine School Entry Policy in Puerto Rico: A Qualitative Study, Vivian Colón-López, Diana T. Medina-Laabes, Roxana Soto Abreu, Olga L. Díaz Miranda, Ana P. Ortiz, María E. Fernández, and Pamela C. Hull

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Content Analysis of Digital Media Coverage of the Human Papillomavirus Vaccine School-Entry Requirement Policy in Puerto Rico, Vivian Colón-López, Vilnery Rivera-Figueroa, Glizette O. Arroyo-Morales, Diana T. Medina-Laabes, Roxana Soto-Abreu, Manuel Rivera-Encarnación, Olga L. Díaz-Miranda, Ana P. Ortiz, Katelyn B. Wells, Coralia Vázquez-Otero, and Pamela C. Hull

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Management of Large Cell Neuroendocrine Carcinoma, Virginia Corbett, Susanne M. Arnold, Lowell B. Anthony, and Aman Chauhan

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Epigenetic Regulation and Post-Translational Modifications of SNAI1 in Cancer Metastasis, Bo Dong and Yadi Wu

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Salvaging Detection of Early-Stage Ovarian Malignancies When CA125 Is Not Informative, Charles J. Dunton, Megan L. Hutchcraft, Rowan G. Bullock, Lesley E. Northrop, and Frederick R. Ueland

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The Context-Dependent Impact of Integrin-Associated CD151 and Other Tetraspanins on Cancer Development and Progression: A Class of Versatile Mediators of Cellular Function and Signaling, Tumorigenesis and Metastasis, Sonia F. Erfani, Hui Hua, Yueyin Pan, Binhua P. Zhou, and Xiuwei H. Yang

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Innate Immune Activation by Checkpoint Inhibition in Human Patient-Derived Lung Cancer Tissues, Teresa W. M. Fan, Richard M. Higashi, Huan Song, Saeed Daneshmandi, Angela L. Mahan, Matthew S. Purdom, Therese J. Bocklage, Thomas A. Pittman, Daheng He, Chi Wang, and Andrew N. Lane

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Through the Lens: Youth Experiences with Cancer in Rural Appalachian Kentucky Using Photovoice, Katie Gaines, Courtney Martin, Chris Prichard, and Nathan L. Vanderford

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Association between Obesity and Histological Tumor Budding in Patients with Nonmetastatic Colon Cancer, Tong Gan, Kurt B. Schaberg, Daheng He, Akila Mansour, Harit Kapoor, Chi Wang, B. Mark Evers, and Therese J. Bocklage

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Protocol for Rapid Assessment of the Efficacy of Novel Wnt Inhibitors Using Zebrafish Models, Meghan G. Haney, Mary Wimsett, Chunming Liu, and Jessica S. Blackburn

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KEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung Cancer, Kristen S. Hill, Anthony McDowell Jr., J. Robert McCorkle, Erin Schuler, Sally R. Ellingson, Rina Plattner, and Jill M. Kolesar

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Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK–SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue, Terry D. Hinds, Jr.; Zachary A. Kipp; Mei Xu; Frederique B. Yiannikouris; Andrew J. Morris; Donald F. Stec; Walter Wahli; and David E. Stec

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The Use of a Book Club to Promote Biomedical Trainee Professional Development, Jenni Ho, Stacy E. Smith, Erin J. Oakley, and Nathan L. Vanderford

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Real-World Evaluation of Universal Germline Screening for Cancer Treatment-Relevant Pharmacogenes, Megan L. Hutchcraft, Nan Lin, Shulin Zhang, Catherine Sears, Kyle Zacholski, Elizabeth A. Belcher, Eric B. Durbin, John L. Villano, Michael J. Cavnar, Susanne M. Arnold, Frederick R. Ueland, and Jill M. Kolesar

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Androgen Receptor Signaling in Prostate Cancer and Therapeutic Strategies, Aasems Jacob, Rishi Raj, Derek B. Allison, and Zin W. Myint

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Real World Clinicopathologic Observations of Patients with Metastatic Solid Tumors Receiving Immune Checkpoint Inhibitor Therapy: Analysis from Kentucky Cancer Registry, Aasems Jacob, Jianrong Wu, Jill M. Kolesar, Eric B. Durbin, Aju Mathew, Susanne Arnold, and Aman Chauhan

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Hierarchical Harmonization of Atom-Resolved Metabolic Reactions across Metabolic Databases, Huan Jin and Hunter N. B. Moseley

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Role of AMPK and Akt in Triple Negative Breast Cancer Lung Colonization, Jeremy Johnson, Zeta Chow, Eun Young Lee, Heidi L. Weiss, B. Mark Evers, and Piotr G. Rychahou

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Development of a Multilevel Intervention to Increase Colorectal Cancer Screening in Appalachia, Aaron J. Kruse-Diehr, Jill M. Oliveri, Robin C. Vanderpool, Mira L. Katz, Paul L. Reiter, Darrell M. Gray II, Michael L. Pennell, Gregory S. Young, Bin Huang, Darla Fickle, Mark Cromo, Melinda Rogers, David Gross, Ashley Gibson, Jeanne Jellison, Michael D. Sarap, Tonia A. Bivens, Tracy D. McGuire, Ann Scheck McAlearney, Timothy R. Huerta, Saurabh Rahurkar, Electra D. Paskett, and Mark B. Dignan

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Clinical Outcomes of Molecular Tumor Boards: A Systematic Review, Kara L. Larson, Bin Huang, Heidi L. Weiss, Pamela C. Hull, Philip M. Westgate, Rachel W. Miller, Susanne M. Arnold, and Jill M. Kolesar

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Genome-Wide Association Meta-Analysis Identifies Pleiotropic Risk Loci for Aerodigestive Squamous Cell Cancers, Corina Lesseur, Aida Ferreiro-Iglesias, James D. McKay, Yohan Bossé, Mattias Johansson, Valerie Gaborieau, Maria Teresa Landi, David C. Christiani, Neil C. Caporaso, Stig E. Bojesen, Christopher I. Amos, Sanjay Shete, Geoffrey Liu, Gadi Rennert, Demetrius Albanes, Melinda C. Aldrich, Adonina Tardon, Chu Chen, Liloglou Triantafillos, John K. Field, and Susanne Arnold

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DNA Repair Pathways in Cancer Therapy and Resistance, Lan-ya Li, Yi-di Guan, Xi-sha Chen, Jin-ming Yang, and Yan Cheng

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Bone in the Breast: A Case Report of a Metaplastic Breast Cancer with Osseous Differentiation, Kyle Luo and Xiaoqin Wang