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Submissions from 2021

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KEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung Cancer, Kristen S. Hill, Anthony McDowell Jr., J. Robert McCorkle, Erin Schuler, Sally R. Ellingson, Rina Plattner, and Jill M. Kolesar

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Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK–SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue, Terry D. Hinds, Jr.; Zachary A. Kipp; Mei Xu; Frederique B. Yiannikouris; Andrew J. Morris; Donald F. Stec; Walter Wahli; and David E. Stec

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The Use of a Book Club to Promote Biomedical Trainee Professional Development, Jenni Ho, Stacy E. Smith, Erin J. Oakley, and Nathan L. Vanderford

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Real-World Evaluation of Universal Germline Screening for Cancer Treatment-Relevant Pharmacogenes, Megan L. Hutchcraft, Nan Lin, Shulin Zhang, Catherine Sears, Kyle Zacholski, Elizabeth A. Belcher, Eric B. Durbin, John L. Villano, Michael J. Cavnar, Susanne M. Arnold, Frederick R. Ueland, and Jill M. Kolesar

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Androgen Receptor Signaling in Prostate Cancer and Therapeutic Strategies, Aasems Jacob, Rishi Raj, Derek B. Allison, and Zin W. Myint

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Real World Clinicopathologic Observations of Patients with Metastatic Solid Tumors Receiving Immune Checkpoint Inhibitor Therapy: Analysis from Kentucky Cancer Registry, Aasems Jacob, Jianrong Wu, Jill M. Kolesar, Eric B. Durbin, Aju Mathew, Susanne Arnold, and Aman Chauhan

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Hierarchical Harmonization of Atom-Resolved Metabolic Reactions across Metabolic Databases, Huan Jin and Hunter N. B. Moseley

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Role of AMPK and Akt in Triple Negative Breast Cancer Lung Colonization, Jeremy Johnson, Zeta Chow, Eun Young Lee, Heidi L. Weiss, B. Mark Evers, and Piotr G. Rychahou

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Development of a Multilevel Intervention to Increase Colorectal Cancer Screening in Appalachia, Aaron J. Kruse-Diehr, Jill M. Oliveri, Robin C. Vanderpool, Mira L. Katz, Paul L. Reiter, Darrell M. Gray II, Michael L. Pennell, Gregory S. Young, Bin Huang, Darla Fickle, Mark Cromo, Melinda Rogers, David Gross, Ashley Gibson, Jeanne Jellison, Michael D. Sarap, Tonia A. Bivens, Tracy D. McGuire, Ann Scheck McAlearney, Timothy R. Huerta, Saurabh Rahurkar, Electra D. Paskett, and Mark B. Dignan

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Clinical Outcomes of Molecular Tumor Boards: A Systematic Review, Kara L. Larson, Bin Huang, Heidi L. Weiss, Pamela C. Hull, Philip M. Westgate, Rachel W. Miller, Susanne M. Arnold, and Jill M. Kolesar

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Genome-Wide Association Meta-Analysis Identifies Pleiotropic Risk Loci for Aerodigestive Squamous Cell Cancers, Corina Lesseur, Aida Ferreiro-Iglesias, James D. McKay, Yohan Bossé, Mattias Johansson, Valerie Gaborieau, Maria Teresa Landi, David C. Christiani, Neil C. Caporaso, Stig E. Bojesen, Christopher I. Amos, Sanjay Shete, Geoffrey Liu, Gadi Rennert, Demetrius Albanes, Melinda C. Aldrich, Adonina Tardon, Chu Chen, Liloglou Triantafillos, John K. Field, and Susanne Arnold

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DNA Repair Pathways in Cancer Therapy and Resistance, Lan-ya Li, Yi-di Guan, Xi-sha Chen, Jin-ming Yang, and Yan Cheng

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Bone in the Breast: A Case Report of a Metaplastic Breast Cancer with Osseous Differentiation, Kyle Luo and Xiaoqin Wang

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Gender Differences in Urothelial Bladder Cancer: Effects of Natural Killer Lymphocyte Immunity, Charles T. Lutz, Lydia Livas, Steven R. Presnell, Morgan Sexton, and Peng Wang

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RORα Suppresses Cancer-Associated Inflammation by Repressing Respiratory Complex I-Dependent ROS Generation, Wei Mao, Gaofeng Xiong, Yuanyuan Wu, Chi Wang, Daret St. Clair, Jai-Da Li, and Ren Xu

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Lapatinib and Poziotinib Overcome ABCB1-Mediated Paclitaxel Resistance in Ovarian Cancer, J. Robert McCorkle, Justin W. Gorski, Jinpeng Liu, McKayla J. Riggs, Anthony B. McDowell Jr., Nan Lin, Chi Wang, Frederick R. Ueland, and Jill M. Kolesar

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Preclinical Evaluation of Artesunate as an Antineoplastic Agent in Ovarian Cancer Treatment, Anthony McDowell Jr., Kristen S. Hill, Joseph Robert McCorkle, Justin W. Gorski, Yilin Zhang, Ameen A. Salahudeen, Frederick R. Ueland, and Jill M. Kolesar

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Untargeted Lipidomics of Non-Small Cell Lung Carcinoma Demonstrates Differentially Abundant Lipid Classes in Cancer vs. Non-Cancer Tissue, Joshua M. Mitchell, Robert M. Flight, and Hunter N. B. Moseley

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A Case Report of Metastatic Castration-Resistant Prostate Cancer Harboring a PTEN Loss, Zin W. Myint, Derek B. Allison, and Carleton S. Ellis

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Evaluation of Glutaminase Expression in Prostate Adenocarcinoma and Correlation with Clinicopathologic Parameters, Zin W. Myint, Ramon C. Sun, Patrick J. Hensley, Andrew C. James, Peng Wang, Stephen E. Strup, Robert J. McDonald, Donglin Yan, William H. St. Clair, and Derek B. Allison

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Enhancing Cancer Care of Rural Dwellers through Telehealth and Engagement (ENCORE): Protocol to Evaluate Effectiveness of a Multi-Level Telehealth-Based Intervention to Improve Rural Cancer Care Delivery, Tuya Pal, Pamela C. Hull, Tatsuki Koyama, Phillip Lammers, Denise Martinez, Jacob McArthy, Emma Schremp, Ann Tezak, Anne Washburn, Jennifer G. Whisenant, and Debra L. Friedman

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The mwtab Python Library for RESTful Access and Enhanced Quality Control, Deposition, and Curation of the Metabolomics Workbench Data Repository, Christian D. Powell and Hunter N. B. Moseley

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A Screen of FDA-Approved Drugs Identifies Inhibitors of Protein Tyrosine Phosphatase 4A3 (PTP4A3 or PRL-3), Dylan R. Rivas, Mark Vincent C. Dela Cerna, Caroline N. Smith, Shilpa Sampathi, Blaine G. Patty, Donghan Lee, and Jessica S. Blackburn

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Neurotensin Regulates Proliferation and Stem Cell Function in the Small Intestine in a Nutrient-Dependent Manner, Stephanie A. Rock, Kai Jiang, Yuanyuan Wu, Yajuan Liu, Jing Li, Heidi L. Weiss, Chi Wang, Jianhang Jia, Tianyan Gao, and B. Mark Evers

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Prevalence of TP-53/Rb-1 Co-Mutation in Large Cell Neuroendocrine Carcinoma, Hoda Saghaeiannejad Esfahani, Cory M. Vela, and Aman Chauhan