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Submissions from 2015

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G9a Is Essential for EMT-Mediated Metastasis and Maintenance of Cancer Stem Cell-Like Characters in Head and Neck Squamous Cell Carcinoma, Shuli Liu, Dongxia Ye, Wenzheng Guo, Wenwen Yu, Yue He, Jingzhou Hu, Yanan Wang, Ling Zhang, Yueling Liao, Hongyong Song, Shuangshuang Zhong, Dongliang Xu, Huijing Yin, Beibei Sun, Xiaofei Wang, Jingyi Liu, Yadi Wu, Binhua P. Zhou, Zhiyuan Zhang, and Jiong Deng

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PPM1A Regulates Antiviral Signaling by Antagonizing TBK1-Mediated STING Phosphorylation and Aggregation, Zexing Li, Ge Liu, Liwei Sun, Yan Teng, Xuejiang Guo, Jianhang Jia, Jiahao Sha, Xiao Yang, Dahua Chen, and Qinmiao Sun

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ZHX2 Enhances the Cytotoxicity of Chemotherapeutic Drugs in Liver Tumor Cells by Repressing MDR1 via Interfering with NF-YA, Hongxin Ma, Xuetian Yue, Lifen Gao, Xiaohong Liang, Wenjiang Yan, Zhenyu Zhang, Haixia Shan, Hualin Zhang, Brett T. Spear, and Chunhong Ma

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Proteomic Analysis of Media from Lung Cancer Cells Reveals Role of 14-3-3 Proteins in Cachexia, Julie B. McLean, Jennifer S. Moylan, Erin M. Wolf Horrell, and Francisco H. Andrade

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AKT Inhibition Overcomes Rapamycin Resistance by Enhancing the Repressive Function of PRAS40 on mTORC1/4E-BP1 Axis, Wenting Mi, Qing Ye, Side Liu, and Qing-Bai She

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Phosphorylation of PCNA by EGFR Inhibits Mismatch Repair and Promotes Misincorporation During DNA Synthesis, Janice Ortega, Jessie Y. Li, Sanghee Lee, Dan Tong, Liya Gu, and Guo-Min Li

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Autophagy Is Induced Upon Platelet Activation and Is Essential for Hemostasis and Thrombosis, Madhu M. Ouseph, Yunjie Huang, Meenakshi Banerjee, Smita Joshi, Laura MacDonald, Yu Zhong, Huijuan Liu, Xianting Li, Binggang Xiang, Guoying Zhang, Masaaki Komatsu, Zhenyu Yue, Zhenyu Li, Brian Storrie, Sidney W. Whiteheart, and Qing Jun Wang

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Plant-Derived SAC domain of PAR-4 (Prostate Apoptosis Response 4) Exhibits Growth Inhibitory Effects in Prostate Cancer Cells, Shayan Sarkar, Sumeet Jain, Vineeta Rai, Dipak K. Sahoo, Sumita Raha, Sujit Suklabaidya, Shantibhusan Senapati, Vivek M. Rangnekar, Indu B. Maiti, and Nrisingha Dey

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Pyruvate Carboxylase Is Critical for Non-Small-Cell Lung Cancer Proliferation, Katherine Sellers, Matthew P. Fox, Michael Bousamra II, Stephen P. Slone, Richard M. Higashi, Donald M. Miller, Yali Wang, Jun Yan, Mariia O. Yuneva, Rahul Deshpande, Andrew N. Lane, and Teresa W-M Fan

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4E-BP1 As an Oncotarget, Qing-Bai She

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Dexamethasone Administration During Definitive Radiation and Temozolomide Renders a Poor Prognosis in a Retrospective Analysis of Newly Diagnosed Glioblastoma Patients, Lisa B. E. Shields, Brent J. Shelton, Andrew Shearer, Li Chen, David A. Sun, Sarah Parsons, T. David Bourne, Renato LaRocca, and Aaron C. Spalding

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Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling, Jiandang Shi, Yajuan Liu, Xuehe Xu, Wen Zhang, Tianxin Yu, Jianhang Jia, and Chunming Liu

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New Approach to Develop Ultra-High Inhibitory Drug Using the Power Function of the Stoichiometry of the Targeted Nanomachine or Biocomplex, Dan Shu, Fengmei Pi, Chi Wang, Peng Zhang, and Peixuan Guo

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Clinical Significance of the Integrin α6β4 in Human Malignancies, Rachel L Stewart and Kathleen L O'Connor

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Targeted DNA Damage at Individual Telomeres Disrupts Their Integrity and Triggers Cell Death, Luxi Sun, Rong Tan, Jianquan Xu, Justin LaFace, Ying Gao, Yanchun Xiao, Myriam Attar, Carola Neumann, Guo-Min Li, Bing Su, Yang Liu, Satoshi Nakajima, Arthur S. Levine, and Li Lan

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Methylseleninic Acid Promotes Antitumour Effects via Nuclear FOXO3a Translocation through Akt Inhibition, Míriam Tarrado-Castellarnau, Roldán Cortés, Miriam Zanuy, Josep Tarragó-Celada, Ibrahim H. Polat, Richard Hill, Teresa W-M Fan, Wolfgang Link, and Marta Cascante

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Test on Existence of Histology Subtype-Specific Prognostic Signatures Among Early Stage Lung Adenocarcinoma and Squamous Cell Carcinoma Patients Using a Cox-Model Based Filter, Suyan Tian, Chi Wang, and Ming-Wen An

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Arsenic Inhibits DNA Mismatch Repair by Promoting EGFR Expression and PCNA Phosphorylation, Dan Tong, Janice Ortega, Christine Kim, Jian Huang, Liya Gu, and Guo-Min Li

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A Case Study of the Impediments to the Commercialization of Research at the University of Kentucky, Nathan L. Vanderford and Elizabeth Marcinkowski

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Fatalistic Beliefs and Completion of the HPV Vaccination Series Among a Sample of Young Appalachian Kentucky Women, Robin C. Vanderpool, Emily Van Meter Dressler, Lindsay R. Stradtman, and Richard A. Crosby

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Epithelial Neoplasia Coincides with Exacerbated Injury and Fibrotic Response in the Lungs of Gprc5a-Knockout Mice Following Silica Exposure, Xiaofei Wang, Dongliang Xu, Yueling Liao, Shuangshuang Zhong, Hongyong Song, Beibei Sun, Binhua P. Zhou, Jiong Deng, and Baohui Han

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Phase III Study of Pasireotide Long-Acting Release in Patients with Metastatic Neuroendocrine Tumors and Carcinoid Symptoms Refractory to Available Somatostatin Analogues, Edward M. Wolin, Barbara Jarzab, Barbro Eriksson, Thomas Walter, Christos Toumpanakis, Michael A. Morse, Paola Tomassetti, Matthias M. Weber, David R. Fogelman, John Ramage, Donald Poon, Brian Gadbaw, Jiang Li, Janice L. Pasieka, Abakar Mahamat, Fredrik Swahn, John Newell-Price, Wasat Mansoor, and Kjell Öberg

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MiR-29/Hsp47 in ECM Network, Ren Xu

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A Less-Biased Analysis of Metalloproteins Reveals Novel Zinc Coordination Geometries, Sen Yao, Robert M. Flight, Eric C. Rouchka, and Hunter N. B. Moseley

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Increased Expression of Fatty Acid Synthase Provides a Survival Advantage to Colorectal Cancer Cells via Upregulation of Cellular Respiration, Yekaterina Y. Zaytseva, Jennifer W. Harris, Mihail I. Mitov, Ji Tae Kim, D. Allan Butterfield, Eun Young Lee, Heidi L. Weiss, Tianyan Gao, and B. Mark Evers