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Submissions from 2023

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Recombinant Protein Vaccines Formulated with Enantio-Specific Cationic Lipid R-DOTAP Induce Protective Cellular and Antibody-Mediated Immune Responses in Mice, Siva Gandhapudi, Hua Shi, Martin Ward, John Peyton Bush, Margarita G. Avdiushko, Karuna Sundarapandiyan, Lauren V. Wood, Mania Dorrani, Afsheen Fatima, Joe Dervan, Frank Bedu-Addo, Greg Conn, Ted M. Ross, and Jerold Woodward

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Metabolic Disruption Induced by mTOR Signaling Pathway Inhibition in Regulatory T-Cell Expansion for Clinical Application, Roberto Gedaly, Gabriel Orozco, Alexandre P. Ancheta, Mackenzie Donoho, Siddharth Desai, Fanny Chapelin, Aman Khurana, Lillie J. Lewis, Cuiping Zhang, and Francesc Marti

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Asparagine restriction enhances CD8+ T cell metabolic fitness and antitumoral functionality through an NRF2-dependent stress response, J. N. Rashida Gnanaprakasam, Bhavana Kushwaha, Lingling Liu, Xuyong Chen, Siwen Kang, Tingting Wang, Teresa A. Cassel, Christopher M. Adams, Richard M. Higashi, David A. Scott, Gang Xin, Zihai Li, Jun Yang, Andrew N. Lane, Teresa Whei-Mei Fan, Ji Zhang, and Ruoning Wang

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Noncovalent interactions that tune the reactivities of the flavins in bifurcating electron transferring flavoprotein, María González-Viegas, Rajiv K. Kar, Anne-Frances Miller, and Maria-Andrea Mroginski

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Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth, Galina Gritsina, Ka-Wing Fong, Xiaodong Lu, Zhuoyuan Lin, Wanqing Xie, Shivani Agarwal, Dong Lin, Gary E. Schiltz, Himisha Beltran, Eva Corey, Colm Morrissey, Yuzhuo Wang, Jonathan C. Zhao, Maha Hussain, and Jindan Yu

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Co-Targeting Nucleus Accumbens Associate 1 and NF-κB Signaling Synergistically Inhibits Melanoma Growth, Lixiang Gu, Xingcong Ren, Chrispus Ngule, Xiaofang Xiong, Jianxun Song, Zhiguo Li, and Jin-Ming Yang

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Impact of the Appalachian Career Training in Oncology (ACTION) Program on Undergraduate Participants, Carol Hanley, Lauren Hudson, Chris Prichard, and Nathan L. Vanderford

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Critical Role of the Sulfiredoxin-Peroxiredoxin IV Axis in Urethane-Induced Non-Small Cell Lung Cancer, Yanning Hao, Hong Jiang, Pratik Thapa, Na Ding, Aziza Alshahrani, Junichi Fujii, Michel B. Toledano, and Qiou Wei

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SYNE1 Mutation Is Associated with Increased Tumor Mutation Burden and Immune Cell Infiltration in Ovarian Cancer, Laura M. Harbin, Nan Lin, Frederick R. Ueland, and Jill M. Kolesar

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Inhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer, Sumati Raj Hasani, Lyndsay E. A. Young, Warren Van Nort, Moumita Banerjee, Dylan R. Rivas, Jinhwan Kim, Xiaopeng Xiong, Ramon C. Sun, Matthew S. Gentry, Hiromi Sesaki, and Tianyan Gao

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Non-contact optical spectroscopy for tumor-sensitive diffuse reflectance and fluorescence measurements on murine subcutaneous tissue models: Monte Carlo modeling and experimental validations, Zahid Hasan, Pranto Soumik Saha, Madison O. Korfhage, and Caigang Zhu

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Production and characterization of monoclonal antibodies to Xenopus proteins, Brett Horr, Ryan Kurtz, Ankit Pandey, Benjamin G. Hoffstrom, Elizabeth Schock, Carole LaBonne, and Dominique Alfandari

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kegg_pull: a software package for the RESTful access and pulling from the Kyoto Encyclopedia of Gene and Genomes, Erik D. Huckvale and Hunter N. B. Moseley

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Benchmark Dataset for Training Machine Learning Models to Predict the Pathway Involvement of Metabolites, Erik D. Huckvale, Christian D. Powell, Huan Jin, and Hunter N. B. Moseley

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Impact of a Cancer Education Curriculum on Appalachian Kentucky Middle and High School Students, Lauren Hudson‑Rose, L. Todd Weiss, and Nathan L. Vanderford

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Green solvent mediated extraction of micro- and nano-plastic particles from water, Jameson R. Hunter, Qi Qiao, Yuxuan Zhang, Qing Shao, Czarena L. Crofcheck, and Jian Shi

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Extracellular vesicle distribution and localization in skeletal muscle at rest and following disuse atrophy, Ahmed Ismaeel, Douglas W. Van Pelt, Zachary Hettinger, Xu Fu, Christopher I. Richards, Timothy A. Butterfield, Jonathan J. Petrocelli, Ivan J. Vechetti Jr., Amy L. Confides, Micah J. Drummond, and Esther E. Dupont-Versteegden

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Copy Number Variation That Influences the Ionizing Radiation Sensitivity of Oral Squamous Cell Carcinoma, Tadahide Izumi, Piotr G. Rychahou, Li Chen, Molly H. Smith, and Joseph Valentino

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Targeting lncRNA DDIT4-AS1 Sensitizes Triple Negative Breast Cancer to Chemotherapy via Suppressing of Autophagy, Ting Jiang, Jiaojiao Zhu, Shilong Jiang, Zonglin Chen, Ping Xu, Rong Gong, Changxin Zhong, Yueying Cheng, Xinyuan Sun, Wenjun Yi, Jinming Yang, Wenhu Zhou, and Yan Cheng

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md_harmonize: A Python Package for Atom-Level Harmonization of Public Metabolic Databases, Huan Jin and Hunter N. B. Moseley

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Phosphatase and Pseudo-Phosphatase Functions of Phosphatase of Regenerating Liver 3 (PRL-3) Are Insensitive to Divalent Metals In Vitro, Jeffery T. Jolly, Ty C. Cheatham, and Jessica S. Blackburn

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In situ microwave fixation provides an instantaneous snapshot of the brain metabolome, Jelena A. Juras, Madison B. Webb, Lyndsay E. A. Young, Kia H. Markussen, Tara R. Hawkinson, Michael D. Buoncristiani, Kayli E. Bolton, Peyton T. Coburn, Meredith I. Williams, Lisa P. Y. Sun, William C. Sanders, Ronald C. Bruntz, Lindsey R. Conroy, Chi Wang, Matthew S. Gentry, Bret N. Smith, and Ramon C. Sun

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Leukocyte Tyrosine Kinase (Ltk) Is the Mendelian Determinant of the Axolotl Melanoid Color Variant, Mirindi Kabangu, Raissa Cecil, Lloyd Strohl II, Nataliya Y. Timoshevskaya, Jeramiah James Smith, and Stephen Randal Voss

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Xylazine Suppresses Fentanyl Consumption During Self-Administration and Induces a Unique Sex-Specific Withdrawal Syndrome That Is Not Altered By Naloxone in Rats, Shailesh N. Khatri, Safiyah M. Sadek, Percell T. Kendrick, Emma O. Bondy, Mei Hong, Sally Pauss, Dan Luo, Thomas E. Prisinzano, Kelly E. Dunn, Julie A. Marusich, Joshua S. Beckmann, Terry D. Hinds Jr., and Cassandra D. Gipson

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Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content, Zachary A. Kipp, Genesee J. Martinez, Evelyn A. Bates, Agil B. Maharramov, Robert M. Flight, Hunter N. B. Moseley, Andrew J. Morris, David E. Stec, and Terry D. Hinds Jr.