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Submissions from 2017

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A Longitudinal Study of the Reciprocal Relationship Between Ever Smoking and Urgency in Early Adolescence, Jessica L. Burris, Elizabeth N. Riley, Gabriella E. Puleo, and Gregory T. Smith

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Integrin α6β4 Upregulates Amphiregulin and Epiregulin Through Base Excision Repair-Mediated DNA Demethylation and Promotes Genome-Wide DNA Hypomethylation, Brittany L. Carpenter, Jinpeng Liu, Lei Qi, Chi Wang, and Kathleen L. O'Connor

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Obesity, Metabolic Factors and Risk of Different Histological Types of Lung Cancer: A Mendelian Randomization Study, Robert Carreras-Torres, Mattias Johansson, Philip C. Haycock, Kaitlin H. Wade, Caroline L. Relton, Richard M. Martin, George Davey Smith, Demetrius Albanes, Melinda C. Aldrich, Angeline Andrew, Susanne M. Arnold, Heike Bickeböller, Stig E. Bojesen, Hans Brunnström, Jonas Manjer, Irene Brüske, Neil E. Caporaso, Chu Chen, David C. Christiani, Warren Jay Christian, Jennifer A. Doherty, Eric J. Duell, John K. Field, Michael P. A. Davies, Michael W. Marcus, Gary E. Goodman, Kjell Grankvist, Aage Haugen, Yun-Chul Hong, and Lambertus A. Kiemeney

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Immune Checkpoint Inhibitors in Neuroendocrine Tumors: A Single Institution Experience With Review of Literature, Aman Chauhan, Millicent Horn, Gray Magee, Kurt Hodges, B. Mark Evers, Susanne Arnold, and Lowell B. Anthony

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Immune Checkpoint Inhibition and the Prevalence of Autoimmune Disorders Among Patients with Lung and Renal Cancer, Sherif M. El-Refai

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Structure and Specificity of a Permissive Bacterial C-Prenyltransferase, Sherif I. Elshahawi, Hongnan Cao, Khaled A. Shaaban, Larissa V. Ponomareva, Thangaiah Subramanian, Mark L. Farman, H. Peter Spielmann, George N. Phillips Jr., Jon S. Thorson, and Shanteri Singh

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Superficial Soft-Tissue Sarcomas Rarely Require Advanced Soft-Tissue Reconstruction Following Resection, William C. Eward, Alexander L. Lazarides, Anthony M. Griffin, Patrick W. O'Donnell, Amir Sternheim, Anne O'Neill, Stefan O. Hofer, Peter C. Ferguson, and Jay S. Wunder

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Long-Term Follow-Up of Cardiac Function and Quality of Life for Patients in NSABP Protocol B-31/NRG Oncology: A Randomized Trial Comparing the Safety and Efficacy of Doxorubicin and Cyclophosphamide (AC) Followed by Paclitaxel With AC Followed by Paclitaxel and Trastuzumab in Patients With Node-Positive Breast Cancer With Tumors Overexpressing Human Epidermal Growth Factor Receptor 2, Patricia A. Ganz, Edward H. Romond, Reena S. Cecchini, Priya Rastogi, Charles E. Geyer Jr., Sandra M. Swain, Jong-Hyeon Jeong, Louis Fehrenbacher, Howard M. Gross, Adam M. Brufsky, Patrick J. Flynn, Tanya A. Wahl, Thomas E. Seay, James L. Wade III, David D. Biggs, James N. Atkins, Jonathan Polikoff, John L. Zapas, Eleftherios P. Mamounas, and Norman Wolmark

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A Naturally Generated Decoy of the Prostate Apoptosis Response-4 Protein Overcomes Therapy Resistance in Tumors, Nikhil Hebbar, Ravshan Burikhanov, Nidhi Shukla, Shirley Qiu, Yanming Zhao, Kojo S. J. Elenitoba-Johnson, and Vivek M. Rangnekar

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Effectiveness of Switching Smoking-Cessation Medications Following Relapse, Bryan W. Heckman, K. Michael Cummings, Karin A. Kasza, Ron Borland, Jessica L. Burris, Geoffrey T. Fong, Ann McNeill, and Matthew J. Carpenter

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Comprehensive Genomic Profiling in Routine Clinical Practice Leads to a Low Rate of Benefit from Genotype-Directed Therapy, Talal Hilal, Mary Nakazawa, Jacob Hodskins, John L. Villano, Aju Mathew, Gaurav Goel, Lars M. Wagner, Susanne M. Arnold, Philip DeSimone, Lowell B. Anthony, and Peter J. Hosein

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Incidence of CNS Tumors in Appalachian Children, Bin Huang, Alice Luo, Eric B. Durbin, Ellen Lycan, Thomas Tucker, Quan Chen, Craig Horbinski, and John L. Villano

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Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid Cells, Sunyoung Hwang, H. Tobias Gustafsson, Ciara O’Sullivan, Gianna Bisceglia, Xinhe Huang, Christian Klose, Andrej Schevchenko, Robert C. Dickson, Paola Cavaliere, Noah Dephoure, and Eduardo M. Torres

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End-of-Life Care and Opioid Use in India: Challenges and Opportunities, Aasems Jacob and Aju Mathew

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CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells, Naser Jafari, Hyunju Kim, Rackhyun Park, Liqing Li, Minsu Jang, Andrew J. Morris, Junsoo Park, and Cai Huang

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Abl Kinase Regulation by BRAF/ERK and Cooperation with Akt in Melanoma, Aditi Jain, Rakshamani Tripathi, Courtney P. Turpin, Chi Wang, and Rina Plattner

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Melatonin and Its Metabolites Protect Human Melanocytes Against UVB-Induced Damage: Involvement of NRF2-Mediated Pathways, Zorica Janjetovic, Stuart G. Jarrett, Elizabeth F. Lee, Cory Duprey, Russel J. Reiter, and Andrzej T. Slominski

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Paracrine Regulation of Melanocyte Genomic Stability: A Focus on Nucleotide Excision Repair, Stuart Gordon Jarrett, Katharine Marie Carter, and John August D'Orazio

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Zhx2 (Zinc Fingers and Homeoboxes 2) Regulates Major Urinary Protein Gene Expression in the Mouse Liver, Jieyun Jiang, Kate Townsend Creasy, Justin Purnell, Martha L. Peterson, and Brett T. Spear

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Fluorinated N,N'-Diarylureas as Novel Therapeutic Agents Against Cancer Stem Cells, Dasha E. Kenlan, Piotr G. Rychahou, Vitaliy M. Sviripa, Heidi L. Weiss, Chunming Liu, David S. Watt, and B. Mark Evers

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Diverse Expression Patterns and Tumorigenic Role of Neurotensin Signaling Components in Colorectal Cancer Cells, Ji Tae Kim, Heidi L. Weiss, and B. Mark Evers

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Emerging Therapies for Stage III Non-Small Cell Lung Cancer: Stereotactic Body Radiation Therapy and Immunotherapy, Sameera S. Kumar, Kristin A. Higgins, and Ronald C. McGarry

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Probing the Metabolic Phenotype of Breast Cancer Cells by Multiple Tracer Stable Isotope Resolved Metabolomics, Andrew N. Lane, Julie Tan, Yali Wang, Jun Yan, Richard M. Higashi, and Teresa W. -M. Fan

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Down Syndrome: Age-Dependence of PiB Binding in Postmortem Frontal Cortex Across the Lifespan, Harry LeVine III, H. Peter Spielmann, Sergey V. Matveev, Francesca Macchiavello Cauvi, M. Paul Murphy, Tina L. Beckett, Katie McCarty, Ira T. Lott, Eric Doran, Frederick A. Schmitt, and Elizabeth Head

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Mitochondrial Phylogenomics of Hemiptera Reveals Adaptive Innovations Driving the Diversification of True Bugs, Hu Li, John Moeller Leavengood Jr., Eric G. Chapman, Daniel Burkhardt, Fan Song, Pei Jiang, Jinpeng Liu, Xuguo Zhou, and Wanzhi Cai