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Submissions from 2015

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A Cytosolic Multiprotein Complex Containing p85α is Required for β-Catenin Activation in Colitis and Colitis-Associated Cancer, Tatiana Goretsky, Emily M. Bradford, Hyunji Ryu, Maryam Tahir, Mary Pat Moyer, Tianyan Gao, Linheng Li, and Terrence A. Barrett

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Inhibition of iNOS as a Novel Effective Targeted Therapy Against Triple-Negative Breast Cancer, Sergio Granados-Principal, Yi Liu, Maria L. Guevara, Elvin Blanco, Dong Soon Choi, Wei Qian, Tejal Patel, Angel A. Rodriguez, Joseph Cusimano, Heidi L. Weiss, Hong Zhao, Melissa D. Landis, Bhuvanesh Dave, Steven S. Gross, and Jenny C. Chang

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Plasma TNF-α and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna-A Randomized, Cross-Over Clinical Study, John Hayslip, Emily Van Meter Dressler, Heidi L. Weiss, Tammy J. Taylor, Mara D. Chambers, Teresa Noel, Sumitra Miriyala, Jeriel T. R. Keeney, Xiaojia Ren, Rukhsana Sultana, Mary Vore, D. Allan Butterfield, Daret St. Clair, and Jeffrey A. Moscow

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The C-terminal Domain (CTD) of Human DNA GlycosylaseNEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD, Pavana M. Hegde, Arijit Dutta, Shiladitya Sengupta, Joy Mitra, Sanjay Adhikari, Alan E. Tomkinson, Guo-Min Li, Istvan Boldogh, Tapas K. Hazra, Sankar Mitra, and Muralidhar L. Hegde

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Noncontact Diffuse Correlation Tomography of Human Breast Tumor, Lian He, Yu Lin, Chong Huang, Daniel Irwin, Margaret M. Szabunio, and Guoqiang Yu

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Truncating Mutation in the Autophagy Gene UVRAG Confers Oncogenic Properties and Chemosensitivity in Colorectal Cancers, Shanshan He, Zhen Zhao, Yongfei Yang, Douglas O'Connell, Xiaowei Zhang, Soohwan Oh, Binyun Ma, Joo-Hyung Lee, Tian Zhang, Bino Varghese, Janae Yip, Sara Dolatshahi Pirooz, Ming Li, Yong Zhang, Guo-Min Li, Sue Ellen Martin, Keigo Machida, and Chengyu Liang

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UV-Independent Induction of Beta Defensin 3 in Neonatal Human Skin Explants, Erin M. Wolf Horrell and John A. D'Orazio

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Detection of PHLPP1α/β in Human and Mouse Brain by Different Anti-PHLPP1 Antibodies, Travis C. Jackson, Hülya Bayir, Milos D. Ikonomovic, Keri Janesko-Feldman, Zaichuan Mi, Tianyan Gao, Edwin K. Jackson, and Patrick M. Kochanek

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Differential Expression and Tumorigenic Function of Neurotensin Receptor 1 in Neuroendocrine Tumor Cells, Ji Tae Kim, Jing Li, Jun Song, Eun Y. Lee, Heidi L. Weiss, Courtney M. Townsend, and B. Mark Evers

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Chemoselective Detection and Discrimination of Carbonyl-Containing Compounds in Metabolite Mixtures by 1H-Detected 15N Nuclear Magnetic Resonance, Andrew N. Lane, Sengodagounder Arumugam, Pawel Lorkiewicz, Richard M. Higashi, Sébastien Laulhé, Michael H. Nantz, Hunter N. B. Moseley, and Teresa W-M Fan

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Regulation of Mammalian Nucleotide Metabolism and Biosynthesis, Andrew N. Lane and Teresa W-M Fan

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13C Tracer Studies of Metabolism in Mouse Tumor Xenografts, Andrew N. Lane, Jun Yan, and Teresa W-M Fan

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RNA Nanoparticle as a Vector for Targeted siRNA Delivery into Glioblastoma Mouse Model, Tae Jin Lee, Farzin Haque, Dan Shu, Ji Young Yoo, Hui Li, Robert A. Yokel, Craig Horbinski, Tae Hyong Kim, Sung-Hak Kim, Chang-Hyuk Kwon, Ichiro Nakano, Balveen Kaur, Peixuan Guo, and Carlo M. Croce

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G9a Is Essential for EMT-Mediated Metastasis and Maintenance of Cancer Stem Cell-Like Characters in Head and Neck Squamous Cell Carcinoma, Shuli Liu, Dongxia Ye, Wenzheng Guo, Wenwen Yu, Yue He, Jingzhou Hu, Yanan Wang, Ling Zhang, Yueling Liao, Hongyong Song, Shuangshuang Zhong, Dongliang Xu, Huijing Yin, Beibei Sun, Xiaofei Wang, Jingyi Liu, Yadi Wu, Binhua P. Zhou, Zhiyuan Zhang, and Jiong Deng

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PPM1A Regulates Antiviral Signaling by Antagonizing TBK1-Mediated STING Phosphorylation and Aggregation, Zexing Li, Ge Liu, Liwei Sun, Yan Teng, Xuejiang Guo, Jianhang Jia, Jiahao Sha, Xiao Yang, Dahua Chen, and Qinmiao Sun

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ZHX2 Enhances the Cytotoxicity of Chemotherapeutic Drugs in Liver Tumor Cells by Repressing MDR1 via Interfering with NF-YA, Hongxin Ma, Xuetian Yue, Lifen Gao, Xiaohong Liang, Wenjiang Yan, Zhenyu Zhang, Haixia Shan, Hualin Zhang, Brett T. Spear, and Chunhong Ma

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Proteomic Analysis of Media from Lung Cancer Cells Reveals Role of 14-3-3 Proteins in Cachexia, Julie B. McLean, Jennifer S. Moylan, Erin M. Wolf Horrell, and Francisco H. Andrade

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AKT Inhibition Overcomes Rapamycin Resistance by Enhancing the Repressive Function of PRAS40 on mTORC1/4E-BP1 Axis, Wenting Mi, Qing Ye, Side Liu, and Qing-Bai She

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Phosphorylation of PCNA by EGFR Inhibits Mismatch Repair and Promotes Misincorporation During DNA Synthesis, Janice Ortega, Jessie Y. Li, Sanghee Lee, Dan Tong, Liya Gu, and Guo-Min Li

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Autophagy Is Induced Upon Platelet Activation and Is Essential for Hemostasis and Thrombosis, Madhu M. Ouseph, Yunjie Huang, Meenakshi Banerjee, Smita Joshi, Laura MacDonald, Yu Zhong, Huijuan Liu, Xianting Li, Binggang Xiang, Guoying Zhang, Masaaki Komatsu, Zhenyu Yue, Zhenyu Li, Brian Storrie, Sidney W. Whiteheart, and Qing Jun Wang

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Plant-Derived SAC domain of PAR-4 (Prostate Apoptosis Response 4) Exhibits Growth Inhibitory Effects in Prostate Cancer Cells, Shayan Sarkar, Sumeet Jain, Vineeta Rai, Dipak K. Sahoo, Sumita Raha, Sujit Suklabaidya, Shantibhusan Senapati, Vivek M. Rangnekar, Indu B. Maiti, and Nrisingha Dey

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Pyruvate Carboxylase Is Critical for Non-Small-Cell Lung Cancer Proliferation, Katherine Sellers, Matthew P. Fox, Michael Bousamra II, Stephen P. Slone, Richard M. Higashi, Donald M. Miller, Yali Wang, Jun Yan, Mariia O. Yuneva, Rahul Deshpande, Andrew N. Lane, and Teresa W-M Fan

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4E-BP1 As an Oncotarget, Qing-Bai She

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Dexamethasone Administration During Definitive Radiation and Temozolomide Renders a Poor Prognosis in a Retrospective Analysis of Newly Diagnosed Glioblastoma Patients, Lisa B. E. Shields, Brent J. Shelton, Andrew Shearer, Li Chen, David A. Sun, Sarah Parsons, T. David Bourne, Renato LaRocca, and Aaron C. Spalding

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Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling, Jiandang Shi, Yajuan Liu, Xuehe Xu, Wen Zhang, Tianxin Yu, Jianhang Jia, and Chunming Liu