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Submissions from 2017

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Phase 1b Trial of Proteasome Inhibitor Carfilzomib with Irinotecan in Lung Cancer and Other Irinotecan-Sensitive Malignancies That Have Progressed on Prior Therapy (Onyx IST Reference Number: CAR-IST-553), Susanne M. Arnold, Kari Chansky, Markos Leggas, Michael A. Thompson, John L. Villano, John Hamm, Rachel E. Sanborn, Glen J. Weiss, Gurkamal Chatta, and Maria Q. Baggstrom

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Ovarian Cancer Incidence Corrected for Oophorectomy, Lauren A. Baldwin, Quan Chen, Thomas C. Tucker, Connie G. White, Robert N. Ore, and Bin Huang

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Complications from Surgeries Related to Ovarian Cancer Screening, Lauren A. Baldwin, Edward J. Pavlik, Emma Ueland, Hannah E. Brown, Kelsey M. Ladd, Bin Huang, Christopher P. DeSimone, John R. Van Nagell, Frederick R. Ueland, and Rachel W. Miller

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Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis, Ravshan Burikhanov, Nikhil Hebbar, Sunil K. Noothi, Nidhi Shukla, James Sledziona, Nathália Araujo, Meghana Kudrimoti, Qing Jun Wang, David S. Watt, Danny R. Welch, Jodi Maranchie, Akihiro Harada, and Vivek M. Rangnekar

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Obesity, Metabolic Factors and Risk of Different Histological Types of Lung Cancer: A Mendelian Randomization Study, Robert Carreras-Torres, Mattias Johansson, Philip C. Haycock, Kaitlin H. Wade, Caroline L. Relton, Richard M. Martin, George Davey Smith, Demetrius Albanes, Melinda C. Aldrich, Angeline Andrew, Susanne M. Arnold, Heike Bickeböller, Stig E. Bojesen, Hans Brunnström, Jonas Manjer, Irene Brüske, Neil E. Caporaso, Chu Chen, David C. Christiani, Warren Jay Christian, Jennifer A. Doherty, Eric J. Duell, John K. Field, Michael P. A. Davies, Michael W. Marcus, Gary E. Goodman, Kjell Grankvist, Aage Haugen, Yun-Chul Hong, and Lambertus A. Kiemeney

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Immune Checkpoint Inhibition and the Prevalence of Autoimmune Disorders Among Patients with Lung and Renal Cancer, Sherif M. El-Refai

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Superficial Soft-Tissue Sarcomas Rarely Require Advanced Soft-Tissue Reconstruction Following Resection, William C. Eward, Alexander L. Lazarides, Anthony M. Griffin, Patrick W. O'Donnell, Amir Sternheim, Anne O'Neill, Stefan O. Hofer, Peter C. Ferguson, and Jay S. Wunder

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Comprehensive Genomic Profiling in Routine Clinical Practice Leads to a Low Rate of Benefit from Genotype-Directed Therapy, Talal Hilal, Mary Nakazawa, Jacob Hodskins, John L. Villano, Aju Mathew, Gaurav Goel, Lars M. Wagner, Susanne M. Arnold, Philip DeSimone, Lowell B. Anthony, and Peter J. Hosein

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Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid Cells, Sunyoung Hwang, H. Tobias Gustafsson, Ciara O’Sullivan, Gianna Bisceglia, Xinhe Huang, Christian Klose, Andrej Schevchenko, Robert C. Dickson, Paola Cavaliere, Noah Dephoure, and Eduardo M. Torres

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CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells, Naser Jafari, Hyunju Kim, Rackhyun Park, Liqing Li, Minsu Jang, Andrew J. Morris, Junsoo Park, and Cai Huang

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Increased ROS Production in Non-Polarized Mammary Epithelial Cells Induces Monocyte Infiltration in 3D Culture, Linzhang Li, Jie Chen, Gaofeng Xiong, Daret K. St. Clair, Wei Xu, and Ren Xu

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Role of Modern Immunotherapy in Gastrointestinal Malignancies: A Review of Current Clinical Progress, Zin W. Myint and Gaurav Goel

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Oxidative Stress-Induced JNK/AP-1 Signaling is a Major Pathway Involved in Selective Apoptosis of Myelodysplastic Syndrome Cells by Withaferin-A, Karine Z. Oben, Sara S. Alhakeem, Mary Kathryn McKenna, Jason A. Brandon, Rajeswaran Mani, Sunil K. Noothi, Jinpeng Liu, Shailaja Akunuru, Sanjit Kumar Dhar, Inder P. Singh, Ying Liang, Chi Wang, Ahmed Abdel-Latif, Harold F. Stills Jr., Daret K. St Clair, Hartmut Geiger, Natarajan Muthusamy, Kaoru Tohyama, Ramesh C. Gupta, and Subbarao Bondada

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Radiation Induced Apoptosis of Murine Bone Marrow Cells is Independent of Early Growth Response 1 (EGR1), Karine Z. Oben, Beth W. Gachuki, Sara S. Alhakeem, Mary Kathryn McKenna, Ying Liang, Daret K. St. Clair, Vivek M. Rangnekar, and Subbarao Bondada

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Symptoms Relevant to Surveillance for Ovarian Cancer, Robert M. Ore, Lauren Baldwin, Dylan Woolum, Erika Elliott, Christiaan Wijers, Chieh-Yu Chen, Rachel W. Miller, Christopher P. DeSimone, Frederick R. Ueland, Richard J. Kryscio, John R. Van Nagell, and Edward J. Pavlik

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Ultrasound Monitoring of Extant Adnexal Masses in the Era of Type 1 and Type 2 Ovarian Cancers: Lessons Learned From Ovarian Cancer Screening Trials, Eleanor L. Ormsby, Edward J. Pavlik, and John P. McGahan

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Ovarian Cancer Screening: Lessons About Effectiveness, Edward J. Pavlik

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Ten Important Considerations for Ovarian Cancer Screening, Edward J. Pavlik

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Effects of Storage Time on Glycolysis in Donated Human Blood Units, Zhen Qi, John D. Roback, and Eberhard O. Voit

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Advances in the Use of Regulatory T-Cells for the Prevention and Therapy of Graft-vs.-Host Disease, Reshma Ramlal and Gerhard C. Hildebrandt

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A Fast and Efficient Python Library for Interfacing with the Biological Magnetic Resonance Data Bank, Andrey Smelter, Morgan Astra, and Hunter N. B. Moseley

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Noninvasive Liquid Diet Delivery of Stable Isotopes into Mouse Models for Deep Metabolic Network Tracing, Ramon C. Sun, Teresa W.-M. Fan, Pan Deng, Richard M. Higashi, Andrew N. Lane, Anh-Thu Le, Timothy L. Scott, Qiushi Sun, Marc O. Warmoes, and Ye Yang

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A Perspective on Ovarian Cancer Biomarkers: Past, Present and Yet-To-Come, Frederick R. Ueland

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Snail Determines the Therapeutic Response to mTOR Kinase Inhibitors by Transcriptional Repression of 4E-BP1, Jun Wang, Qing Ye, Yanan Cao, Yubin Guo, Xiuping Huang, Wenting Mi, Side Liu, Chi Wang, Hsin-Sheng Yang, Binhua P. Zhou, B. Mark Evers, and Qing-Bai She

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Adipocytes Activate Mitochondrial Fatty Acid Oxidation and Autophagy to Promote Tumor Growth in Colon Cancer, Yang-An Wen, Xiaopeng Xing, Jennifer W. Harris, Yekaterina Y. Zaytseva, Mihail I. Mitov, Dana L. Napier, Heidi L. Weiss, B. Mark Evers, and Tianyan Gao