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Submissions from 2017

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Potent Anti-Cancer Effects of Less Polar Curcumin Analogues on Gastric Adenocarcinoma and Esophageal Squamous Cell Carcinoma Cells, Fatemeh Alibeiki, Naser Jafari, Maryam Karimi, and Hadi Peeri Dogaheh

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Phase 1b Trial of Proteasome Inhibitor Carfilzomib with Irinotecan in Lung Cancer and Other Irinotecan-Sensitive Malignancies That Have Progressed on Prior Therapy (Onyx IST Reference Number: CAR-IST-553), Susanne M. Arnold, Kari Chansky, Markos Leggas, Michael A. Thompson, John L. Villano, John Hamm, Rachel E. Sanborn, Glen J. Weiss, Gurkamal Chatta, and Maria Q. Baggstrom

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Ovarian Cancer Incidence Corrected for Oophorectomy, Lauren A. Baldwin, Quan Chen, Thomas C. Tucker, Connie G. White, Robert N. Ore, and Bin Huang

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Complications from Surgeries Related to Ovarian Cancer Screening, Lauren A. Baldwin, Edward J. Pavlik, Emma Ueland, Hannah E. Brown, Kelsey M. Ladd, Bin Huang, Christopher P. DeSimone, John R. Van Nagell, Frederick R. Ueland, and Rachel W. Miller

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Exploring Cancer Metabolism Using Stable Isotope-Resolved Metabolomics (SIRM), Ronald C. Bruntz, Andrew N. Lane, Richard M. Higashi, and Teresa W. -M. Fan

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Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis, Ravshan Burikhanov, Nikhil Hebbar, Sunil K. Noothi, Nidhi Shukla, James Sledziona, Nathália Araujo, Meghana Kudrimoti, Qing Jun Wang, David S. Watt, Danny R. Welch, Jodi Maranchie, Akihiro Harada, and Vivek M. Rangnekar

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Integrin α6β4 Upregulates Amphiregulin and Epiregulin Through Base Excision Repair-Mediated DNA Demethylation and Promotes Genome-Wide DNA Hypomethylation, Brittany L. Carpenter, Jinpeng Liu, Lei Qi, Chi Wang, and Kathleen L. O'Connor

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Obesity, Metabolic Factors and Risk of Different Histological Types of Lung Cancer: A Mendelian Randomization Study, Robert Carreras-Torres, Mattias Johansson, Philip C. Haycock, Kaitlin H. Wade, Caroline L. Relton, Richard M. Martin, George Davey Smith, Demetrius Albanes, Melinda C. Aldrich, Angeline Andrew, Susanne M. Arnold, Heike Bickeböller, Stig E. Bojesen, Hans Brunnström, Jonas Manjer, Irene Brüske, Neil E. Caporaso, Chu Chen, David C. Christiani, Warren Jay Christian, Jennifer A. Doherty, Eric J. Duell, John K. Field, Michael P. A. Davies, Michael W. Marcus, Gary E. Goodman, Kjell Grankvist, Aage Haugen, Yun-Chul Hong, and Lambertus A. Kiemeney

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Immune Checkpoint Inhibition and the Prevalence of Autoimmune Disorders Among Patients with Lung and Renal Cancer, Sherif M. El-Refai

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Superficial Soft-Tissue Sarcomas Rarely Require Advanced Soft-Tissue Reconstruction Following Resection, William C. Eward, Alexander L. Lazarides, Anthony M. Griffin, Patrick W. O'Donnell, Amir Sternheim, Anne O'Neill, Stefan O. Hofer, Peter C. Ferguson, and Jay S. Wunder

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Long-Term Follow-Up of Cardiac Function and Quality of Life for Patients in NSABP Protocol B-31/NRG Oncology: A Randomized Trial Comparing the Safety and Efficacy of Doxorubicin and Cyclophosphamide (AC) Followed by Paclitaxel With AC Followed by Paclitaxel and Trastuzumab in Patients With Node-Positive Breast Cancer With Tumors Overexpressing Human Epidermal Growth Factor Receptor 2, Patricia A. Ganz, Edward H. Romond, Reena S. Cecchini, Priya Rastogi, Charles E. Geyer Jr., Sandra M. Swain, Jong-Hyeon Jeong, Louis Fehrenbacher, Howard M. Gross, Adam M. Brufsky, Patrick J. Flynn, Tanya A. Wahl, Thomas E. Seay, James L. Wade III, David D. Biggs, James N. Atkins, Jonathan Polikoff, John L. Zapas, Eleftherios P. Mamounas, and Norman Wolmark

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Comprehensive Genomic Profiling in Routine Clinical Practice Leads to a Low Rate of Benefit from Genotype-Directed Therapy, Talal Hilal, Mary Nakazawa, Jacob Hodskins, John L. Villano, Aju Mathew, Gaurav Goel, Lars M. Wagner, Susanne M. Arnold, Philip DeSimone, Lowell B. Anthony, and Peter J. Hosein

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Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid Cells, Sunyoung Hwang, H. Tobias Gustafsson, Ciara O’Sullivan, Gianna Bisceglia, Xinhe Huang, Christian Klose, Andrej Schevchenko, Robert C. Dickson, Paola Cavaliere, Noah Dephoure, and Eduardo M. Torres

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End-of-Life Care and Opioid Use in India: Challenges and Opportunities, Aasems Jacob and Aju Mathew

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CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells, Naser Jafari, Hyunju Kim, Rackhyun Park, Liqing Li, Minsu Jang, Andrew J. Morris, Junsoo Park, and Cai Huang

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Melatonin and Its Metabolites Protect Human Melanocytes Against UVB-Induced Damage: Involvement of NRF2-Mediated Pathways, Zorica Janjetovic, Stuart G. Jarrett, Elizabeth F. Lee, Cory Duprey, Russel J. Reiter, and Andrzej T. Slominski

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The Melanocortin Signaling cAMP Axis Accelerates Repair and Reduces Mutagenesis of Platinum-Induced DNA Damage, Stuart G. Jarrett, Katharine M. Carter, Brent J. Shelton, and John A. D'Orazio

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Zhx2 (Zinc Fingers and Homeoboxes 2) Regulates Major Urinary Protein Gene Expression in the Mouse Liver, Jieyun Jiang, Kate Townsend Creasy, Justin Purnell, Martha L. Peterson, and Brett T. Spear

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Diverse Expression Patterns and Tumorigenic Role of Neurotensin Signaling Components in Colorectal Cancer Cells, Ji Tae Kim, Heidi L. Weiss, and B. Mark Evers

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Emerging Therapies for Stage III Non-Small Cell Lung Cancer: Stereotactic Body Radiation Therapy and Immunotherapy, Sameera S. Kumar, Kristin A. Higgins, and Ronald C. McGarry

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Increased ROS Production in Non-Polarized Mammary Epithelial Cells Induces Monocyte Infiltration in 3D Culture, Linzhang Li, Jie Chen, Gaofeng Xiong, Daret K. St. Clair, Wei Xu, and Ren Xu

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The Role of Talin2 in Breast Cancer Tumorigenesis and Metastasis, Liqing Li, Xiang Li, Lei Qi, Piotr G. Rychahou, Naser Jafari, and Cai Huang

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Nanoparticle Delivery of miR-34a Eradicates Long-Term-Cultured Breast Cancer Stem Cells via Targeting C22ORF28 Directly, Xiaoti Lin, Weiyu Chen, Fengqin Wei, Binhua P. Zhou, Mien-Chie Hung, and Xiaoming Xie

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Stabilization of the Transcription Factors Slug and Twist by the Deubiquitinase Dub3 is a Key Requirement for Tumor Metastasis, Yiwei Lin, Yu Wang, Qing Shi, Qian Yu, Cuicui Liu, Jing Feng, Jiong Deng, B. Mark Evers, Binhua P. Zhou, and Yadi Wu

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Role of Modern Immunotherapy in Gastrointestinal Malignancies: A Review of Current Clinical Progress, Zin W. Myint and Gaurav Goel