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Submissions from 2025

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Nonresolving Neuroinflammation Regulates Axon Regeneration in Chronic Spinal Cord Injury, Andrew N. Stewart, Christopher C. Bosse-Joseph, Reena Kumari, William M. Bailey, Kennedy A. Park, Victoria K. Slone, and John C. Gensel

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Alternate quantification approaches for cold-induced vasodilation in human glabrous skin, J. A. Stout, D. E. Gerow, P. C. Clegg, K. Metzler-Wilson, and T. E. Wilson

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Satellite cells choreograph an immune cell-fibrogenic cell circuit during mechanical loading in geriatric skeletal muscle, Nicholas T. Thomas, Camille R. Brightwell, Allison M. Owen, Alexander R. Keeble, Sabin Khadgi, Yuan Wen, Christopher S. Fry, and Kevin A. Murach

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Targeting mTOR in myeloid cells prevents infection-associated inflammation, Yohana C. Toner, Jazz Munitz, Geoffrey Prevot, Judit Morla-Folch, William Wang, Yuri van Elsas, Bram Priem, Jeroen Deckers, Tom Anbergen, Thijs J. Beldman, Eliane E.S. Brechbühl, Muhammed D. Aksu, Athanasios Ziogas, Sebastian A. Sarlea, Mumin Ozturk, Zhenhua Zhang, Wenchao Li, Yang Li, Alexander Maier, Jessica C. Fernandes, Glenn A.O. Cremers, Bas van Genabeek, Joost H.C.M. Kreijtz, Esther Lutgens, Niels P. Riksen, Henk M. Janssen, Serge H.M. Söntjens, and Freek J.M. Hoeben

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B cells upregulate NMDARs, respond to extracellular glutamate, and express mature BDNF to protect the brain from ischemic injury, Vanessa O. Torres, Jadwiga Turchan-Cholewo, Mary K. Colson, Pavel Yanev, Daimen R.S. Britsch, Katherine M. Cotter, Annabel M. McAtee, Thomas A. Ujas, Domenico Mercurio, Xiangmei Kong, Erik J. Plautz, Chaitanya R. Joshi, Takeshi K. Matsui, Eiichiro Mori, Ambar Cajigas-Hernandez, Kielen Zuurbier, Steven Estus, Mark P. Goldberg, Nancy L. Monson, and Ann M. Stowe

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PPARα regulates ER–lipid droplet protein Calsyntenin-3β to promote ketogenesis in hepatocytes, Lauren F. Uchiyama, Alexander Nguyen, Kevin Qian, Liujuan Cui, Khoi T. Pham, Xu Xiao, Yajing Gao, Yuta Shimanaka, Marcus J. Tol, Laurent Vergnes, Karen Reue, and Peter Tontonoz

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APOE-Targeted Therapeutics for Alzheimer’s Disease, Hussein N. Yassine, Cristelle Hugo, Bernadette O’Donovan, Isaiah O. Stephens, Lance A. Johnson, Gregory Cole, Julia Tcw, Jan Johansson, Kassandra Kisler, and Ornit Chiba-Falek

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The Core Circadian Clock Factor, Bmal1, Transduces Sex-specific Differences in Both Rhythmic and Nonrhythmic Gene Expression in the Mouse Heart, Xiping Zhang, Spencer B. Procopio, Haocheng Ding, Maya G. Semel, Elizabeth A. Schroder, Mark R. Viggars, Tanya S. Seward, Ping Du, Kevin Wu, Sidney R. Johnson, Abhilash Prabhat, David J. Schneider, Isabel G. Stumpf, Ezekiel R. Rozmus, Zhiguang Huo, Brian P. Delisle, and Karyn A. Esser

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Thermoneutrality Does Not Affect Angiotensin II–Induced Aortic Aneurysms in Hypercholesterolemic Mice, Liyuan Zhu, Bowen Li, Michael K. Franklin, Deborah A. Howatt, Yuriko Katsumata, Alan Daugherty, and Hong S. Lu

Submissions from 2024

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Acute gastrointestinal permeability after traumatic brain injury in mice precedes a bloom in Akkermansia muciniphila supported by intestinal hypoxia, Anthony J. DeSana, Steven Estus, Terrence A. Barrett, and Kathryn E. Saatman

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A practical guide to data management and sharing for biomedical laboratory researchers., K Fouad, R Vavrek, M C Surles-Zeigler, J R Huie, H L Radabaugh, G G Gurkoff, U Visser, J S Grethe, M E Martone, A R Ferguson, John C. Gensel, and A Torres-Espin

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Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference., Courtney M Kloske, Michael E Belloy, Elizabeth E Blue, Gregory R Bowman, Maria C Carrillo, Xiaoying Chen, Ornit Chiba-Falek, Albert A Davis, Gilbert Di Paolo, Francesca Garretti, David Gate, Lesley R. Golden, Jay W Heinecke, Joachim Herz, Yadong Huang, Costantino Iadecola, Lance A Johnson, Takahisa Kanekiyo, Celeste M Karch, Anastasia Khvorova, Sascha J Koppes-den Hertog, Bruce T Lamb, Paige E Lawler, Yann Le Guen, Alexandra Litvinchuk, Chia-Chen Liu, Simin Mahinrad, Edoardo Marcora, Claudia Marino, Danny M Michaelson, Justin J Miller, Josh M. Morganti, Priyanka S Narayan, Michel S Naslavsky, Marlies Oosthoek, Kapil V Ramachandran, Abhirami Ramakrishnan, Ana-Caroline Raulin, Aiko Robert, Rasha N M Saleh, Claire Sexton, Nilomi Shah, Francis Shue, Isabel J Sible, Andrea Soranno, Michael R Strickland, Julia Tcw, Manon Thierry, Li-Huei Tsai, Ryan A Tuckey, Jason D Ulrich, Rik van der Kant, Na Wang, Cheryl L Wellington, Stacie C Weninger, Hussein N Yassine, Na Zhao, Guojun Bu, Alison M Goate, and David M Holtzman

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Asthmatic patients with high serum amyloid A have proinflammatory HDL: Implications for augmented systemic and airway inflammation., Xianglan Yao, Maryann Kaler, Xuan Qu, Rama Satyanarayana Raju Kalidhindi, Denis Sviridov, Amaury Dasseux, Eric Barr, Karen Keeran, Kenneth R. Jeffries, Zu-Xi Yu, Meixia Gao, Scott Gordon, Amisha V. Barochia, Joni Mills, Shahid Shahid, Nargues A. Weir, Or Kalchiem-Dekel, Patricia Theard, Martin P. Playford, Mario Stylianou, Wendy Fitzgerald, Alan T. Remaley, and Stewart J. Levine

Submissions from 2022

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Key Factors for Improving Rigor and Reproducibility: Guidelines, Peer Reviews, and Journal Technical Reviews, Hong S. Lu and Alan Daugherty

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β-Aminopropionitrile-Induced Aortic Aneurysm and Dissection in Mice, Hisashi Sawada, Zachary A. Beckner, Sohei Ito, Alan Daugherty, and Hong S. Lu

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Advanced Age and Neurotrauma Diminish Glutathione and Impair Antioxidant Defense after Spinal Cord Injury, Andrew N. Stewart, Ethan P. Glaser, Caitlin A. Mott, William M. Bailey, Patrick G. Sullivan, Samir P. Patel, and John C. Gensel

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APOE Genetics Influence Murine Gut Microbiome, Diana J. Zajac, Stefan J. Green, Lance A. Johnson, and Steven Estus

Submissions from 2021

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CERTL Reduces C16 Ceramide, Amyloid-β Levels, and Inflammation in a Model of Alzheimer’s Disease, Simone M. Crivelli, Qian Luo, Jo A. A. Stevens, Caterina Giovagnoni, Daan van Kruining, Gerard Bode, Sandra den Hoedt, Barbara Hobo, Anna-Lena Scheithauer, Jochen Walter, Monique T. Mulder, Christopher Exley, Matthew Mold, Michelle M. Mielke, Helga E. De Vries, Kristiaan Wouters, Daniel L. A. van den Hove, Dusan Berkes, María Dolores Ledesma, Joost Verhaagen, Mario Losen, Erhard Bieberich, and Pilar Martinez-Martinez

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Single-Cell Analysis of Aneurysmal Aortic Tissue in Patients with Marfan Syndrome Reveals Dysfunctional TGF-β Signaling, Ashley Dawson, Yanming Li, Yang Li, Pingping Ren, Hernan G. Vasquez, Chen Zhang, Kimberly R. Rebello, Waleed Ageedi, Alon R. Azares, Aladdein Burchett Mattar, Mary Burchett Sheppard, Hong S. Lu, Joseph S. Coselli, Lisa A. Cassis, Alan Daugherty, Ying H. Shen, and Scott A. LeMaire

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Editorial: Perturbations in Metabolic Cues: Implications for Adverse Cardiac Function Leading to Sudden Cardiac Death, Brian P. Delisle and Ademuyiwa S. Aromolaran

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APOΕ4 Lowers Energy Expenditure in Females and Impairs Glucose Oxidation by Increasing Flux through Aerobic Glycolysis, Brandon C. Farmer, Holden C. Williams, Nicholas A. Devanney, Margaret A. Piron, Grant K. Nation, David J. Carter, Adeline E. Walsh, Rebika Khanal, Lyndsay E. A. Young, Jude C. Kluemper, Gabriela Hernandez, Elizabeth J. Allenger, Rachel Mooney, Lesley R. Golden, Cathryn T. Smith, J. Anthony Brandon, Vedant A. Gupta, Philip A. Kern, Matthew S. Gentry, Josh M. Morganti, Ramon C. Sun, and Lance A. Johnson

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Water Exchange Rate across the Blood-Brain Barrier Is Associated with CSF Amyloid-β 42 in Healthy Older Adults, Brian T. Gold, Xingfeng Shao, Tiffany L. Sudduth, Gregory A. Jicha, Donna M. Wilcock, Elayna R. Seago, and Danny J. J. Wang

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Effect of Metformin on the High-Density Lipoprotein Proteome in Youth with Type 1 Diabetes, Evgenia Gourgari, Kristen J. Nadeau, Laura Pyle, Martin P. Playford, Junfeng Ma, Nehal N. Mehta, Alan T. Remaley, and Scott M. Gordon

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Differential Leukocyte and Platelet Profiles in Distinct Models of Traumatic Brain Injury, William Brad Hubbard, Meenakshi Banerjee, Hemendra J. Vekaria, Kanakanagavalli Shravani Prakhya, Smita Joshi, Qingjun Wang, Kathryn E. Saatman, Sidney W. Whiteheart, and Patrick G. Sullivan

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No Effect of Hypercholesterolemia on Elastase-Induced Experimental Abdominal Aortic Aneurysm Progression, Toru Ikezoe, Takahiro Shoji, Jia Guo, Fanru Shen, Hong S. Lu, Alan Daugherty, Masao Nunokawa, Hiroshi Kubota, Masaaki Miyata, Baohui Xu, and Ronald L. Dalman