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Submissions from 2026

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Microvascular endothelial scavenger receptor class B type I protects against heart failure with preserved ejection fraction by inhibiting T-cell cardiotropism, Yufei Wu, Xiaomei Yang, Yu Bai, Chenze Li, Peng Wang, Qing Xu, Hui Li, Xiaoli Rao, Yangkai Xu, Jie Chen, Huanhuan Cao, Qi Zhang, Mingming Zhao, Rui Zhan, Xue Fan, Yuedong Hou, Jie Liu, Hong S. Lu, Tianyun Wang, Wei Dong Gao, Linzhang Huang, Han Xiao, Lingyun Zu, Alan Daugherty, Mingguo Xu, and Lemin Zheng

Submissions from 2025

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Programmable scanning diffuse speckle contrast imaging of cerebral blood flow, Faezeh Akbari, Xuhui Liu, Fatemeh Hamedi, Mehrana Mohtasebi, Li Chen, Lei Chen, and Guoqiang Yu

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Endothelium- and Fibroblast-Derived C-Type Natriuretic Peptide Prevents the Development and Progression of Aortic Aneurysm, Aisah A. Aubdool, Amie J. Moyes, Cristina Perez-Ternero, Reshma S. Baliga, Jaspinder Singh Sanghera, M. Taaha Syed, Kareemah Jaigirdar, Anmolpreet K. Panesar, Janice C. Tsui, Yanming Li, Hernan G. Vasquez, Ying H. Shen, Scott A. Lemaire, Juliette Raffort, Ziad Mallat, Hong S. Lu, Alan Daugherty, and Adrian J. Hobbs

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Right ventricular vulnerability, Cheavar A. Blair, Bryana M. Levitan, Tori Brown, Nakeya Dewaswala, and Amit Arbune

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From gains to liver pain, Benjamin I. Burke, John J. McCarthy, and Ahmed Ismaeel

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Methylome–proteome integration after late-life voluntary exercise training reveals regulation and target information for improved skeletal muscle health, Toby L Chambers, Andrea Dimet-Wiley, Alexander R Keeble, Amin Haghani, Wen-Juo Lo, Gyumin Kang, Robert Brooke, Steve Horvath, Christopher S Fry, Stanley J Watowich, Yuan Wen, and Kevin A Murach

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At the Nexus Between Epigenetics and Senescence, Toby L. Chambers, Jaden Wells, Pieter Jan Koopmans, Francielly Morena, Zain B. Malik, Nicholas P. Greene, Antonio Filareto, Michael Franti, Patrizia Sini, Harald Weinstabl, Robert T. Brooke, Milda Milčiūtė, Juozas Gordevičius, Steve Horvath, Yuan Wen, Cory M. Dungan, and Kevin A. Murach

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Differential effects of myosin activators on myocardial contractile function in nonfailing and failing human hearts, Joohee Choi, Patrick T. Wood, Joshua B. Holmes, Katherine L. Dominic, Cristobal G. dos Remedios, Kenneth S. Campbell, and Julian E. Stelzer

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Mechanisms matter, Nicole L. Collins and Kenneth S. Campbell

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ATP-sensitive potassium channels alter glycolytic flux to modulate cortical activity and sleep, Nicholas J. Constantino, Caitlin M. Carroll, Holden C. Williams, Hemendra J. Vekaria, Carla M. Yuede, Kai Saito, Patrick W. Sheehan, J. Andy Snipes, Marcus E. Raichle, Erik S. Musiek, Patrick G. Sullivan, Josh M. Morganti, Lance A. Johnson, and Shannon L. Macauley

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Circadian influences on sudden cardiac death and cardiac electrophysiology, Brian P. Delisle, Abhilash Prabhat, Don E. Burgess, Isabel G. Stumpf, John J. Mccarthy, Spencer B. Procopio, Xiping Zhang, Karyn A. Esser, and Elizabeth A. Schroder

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Distinct odorant receptor response patterns to aliphatic odorants in freely behaving mice, Claire A. de March, Patrick Breheny, William B. Titlow, Hiroaki Matsunami, and Timothy S. McClintock

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Sex-based differences in the long-term fate of hippocampal neurons born after a traumatic brain injury, Hannah C. Downing, Ashley B. Glover, Jessica E. Gebhardt, Katherine L. Thompson, and Kathryn E. Saatman

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Racial and Rural Disparities in Financial Toxicity and Healthcare Transitions Among Adolescent and Young Adult Cancer Survivors in Kentucky, Jean S. Edward, Brent J. Shelton, Lauren Corum, Haafsah Fariduddin, Katie Brown, John A. D’Orazio, and Kimberly D. Northrip

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High-throughput screens identify genotype-specific therapeutics for channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, and Björn C. Knollmann

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Mirabegron treatment reduces myofibroblasts and CXCR2 expression in adipose tissue in obesity, Brian S. Finlin, Hasiyet Memetimin, Philip M. Westgate, Jin Chen, Esther E. Dupont-Versteegden, and Philip A. Kern

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APOE4 reshapes the lipid droplet proteome and modulates microglial inflammatory responses, Cassi M. Friday, Isaiah O. Stephens, Cathryn T. Smith, Sangderk Lee, Diksha Satish, Nicholas A. Devanney, Sarah Cohen, Josh M. Morganti, Scott M. Gordon, and Lance A. Johnson

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S6K1 is a Targetable Vulnerability in Tumors Exhibiting Plasticity and Therapy Resistance, Saptadwipa Ganguly, Ravshan Burikhanov, Vitaliy M. Sviripa, Sally Ellingson, Jieyun Jiang, Christian M. Gosser, David Orren, Eva M. Goellner, Gautham G. Shenoy, Mahadev Rao, John D’orazio, Christine F. Brainson, Chang Guo Zhan, Peter H. Spielmann, David S. Watt, and Vivek M. Rangnekar

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Stress relaxation rates of myocardium from failing and non-failing hearts, Marissa Gionet-Gonzales, Gianna Gathman, Jonah Rosas, Kyle Y. Kunisaki, Dominique Gabriele P. Inocencio, Niki Hakami, Gregory N. Milburn, Angela A. Pitenis, Kenneth S. Campbell, Beth L. Pruitt, and Ryan S. Stowers

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Resistance exercise and mechanical overload upregulate vimentin for skeletal muscle remodeling, Joshua S. Godwin, J. Max Michel, Cleiton A. Libardi, Andreas N. Kavazis, Christopher S. Fry, Andrew D. Frugé, Mariah McCashland, Ivan J. Vechetti, John J. McCarthy, C. Brooks Mobley, and Michael D. Roberts

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Skeletal Muscle Stem Cell Mitochondria Are Transferred to Muscle Fibers in Response to a Hypertrophic Stimulus, Jensen Goh, Julia G. Williams, Sarah E. Ogle, Jai K. Joshi, Logan N. Scott, Benjamin Burke, Alex R. Keeble, Nicholas T. Thomas, Christopher S. Fry, Ahmed Ismaeel, and John J. McCarthy

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APOE4 to APOE2 allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition, Lesley R. Golden, Dahlia S. Siano, Isaiah O. Stephens, Steven M. MacLean, Kai Saito, Georgia L. Nolt, Jessica L. Funnell, Akhil V. Pallerla, Sangderk Lee, Cathryn Smith, Jing Chen, Haining Zhu, Clairity Voy, Callie M. Whitus, Gabriela Hernandez, Brandon C. Farmer, Kumar Pandya, Dale O. Cowley, Shannon L. Macauley, Scott M. Gordon, Josh M. Morganti, and Lance A. Johnson

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Exploring the Impact of Mitoquinone Supplementation on Glycan Profiles in a Repeated Mild Traumatic Brain Injury Mouse Model, Mona Goli, Akeem Sanni, Sakshi Gautam, Khalil Mallah, W. Brad Hubbard, Mohammad Reslan, Muhammad Ali Haidar, Karim Halabi, Joseph Walker, Stefania Mondello, Firas Kobeissy, and Yehia Mechref

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Inhibition of astrocyte signaling leads to sex-specific changes in microglia phenotypes in a diet-based model of cerebral small vessel disease, Jenna L. Gollihue, Khine Zin Aung, Colin B. Rogers, Leopoldine B. Galopin, Nicholas A. Wright, Pradoldej Sompol, Erica M. Weekman, Yuriko Katsumata, Josh M. Morganti, and Christopher M. Norris

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Trajectories of Recovery after ACutE and cRitical illness (TRACER), Felipe González-Seguel, Louisa A. Summers, Lindsey E. Fresenko, Douglas E. Long, Logan N. Scott, Stacey A. Slone, Srushan Shankara Bhaktula, Yuan Wen, Benjamin F. Miller, Peter E. Morris, Amy L. Salyer, Anna G. Kalema, Ashley A. Montgomery-Yates, Esther E. Dupont-Versteegden, Kirby P. Mayer, Isabelle D. Bach, Davis A. Englund, Zachary R. Hettinger, Ahmed Ismaeel, Audrey M. Johnson, Philip A. Kern, Gerald V. Klim, Allison M. Owen, Jocelyn C. Porchia, and Heba H. Qaissi