Submissions from 2026
Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport, Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, and Mireille I. Ouimet
Skeletal muscle methylome-transcriptome disruptions during the onset and progression of colorectal cancer-induced cachexia, Ana Regina Cabrera, Ronald G. Jones, Eleanor R. Shrems, Francielly Morena, Yuan Wen, Tyrone A. Washington, Kevin A. Murach, and Nicholas P. Greene
Sustained increase in extracellular ATP in the lung induced by chronic inhalation exposure to nitrogen dioxide, Nai Ju Chan, Yueh Yin Chen, Chun Chun Hsu, You Shuei Lin, Maxwell Zakeri, Mehdi Khosravi, and Lu Yuan Lee
Early microglial response to amyloid plaques drives sleep loss in Alzheimer’s disease, Nicholas J. Constantino, Riley E. Irmen, Matthew J. Lanning, Sierra M. Turner, Clair C. Ashley, Caitlin M. Carroll, Evan M. Neary, Dave Rubinow, J. Andy Snipes, and Shannon L. Macauley
Pediatric CHOP chemotherapy acutely disrupts satellite-cell dynamics and blunts muscle mass in a sex-specific manner, Jainil Daredia, Marc A. Magaña, Carla M.C. Nascimento, Jaden M. Wells, Nicholas T. Thomas, Yuan Wen, Savannah V. Rauschendorfer, Cory M. Dungan, and Michael P. Wiggs
BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability, Brian P. Delisle, Ezekiel Rozmus, Abhilash Prabhat, Spencer B. Procopio, Xiping Zhang, Emilia Entcheva, Karyn A. Esser, and Elizabeth Schroder
High-throughput screens identify genotype-specific therapeutics for channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, and Björn C. Knollmann
C/EBPα is Essential for Gonadal but Not Inguinal White Adipose Tissue Formation in Mice, Krista Y. Hu, Yu-Lin Ma, Esme A. Dodge, Olivia A. B. Maguire, Caio V. Matias, Ryan K. Barney, Hector S. Himede, Juliana Gomez Pardo, Miriam Cepeda, Scott M. Gordon, and Robert C. Bauer
S100A4-lineage cells contribute modestly to angiotensin II-mediated thoracic aortic aneurysms through angiotensin II type 1a receptor in mice, Sohei Ito, Jeff Z. Chen, Deborah A. Howatt, Jessica J. Moorleghen, Hong S. Lu, Alan Daugherty, and Hisashi Sawada
Building resilience when disaster strikes, Anna G. Kalema, Felipe González-Seguel, Louisa A. Summers, Esther E. Dupont-Versteegden, Ashley A. Montgomery-Yates, and Kirby P. Mayer
Muscle atrophy after ACL reconstruction involves molecular mechanisms beyond unloading, Alexander R. Keeble, Gonzalez Velez Sara, Nicholas T. Thomas, Allison M. Owen, Austin V. Stone, Darren L. Johnson, Julián Candia, Luigi Ferrucci, Marco Narici, Esther E. Dupont-Versteegden, Brian Noehren, Martino V. Franchi, and Christopher S. Fry
The Age-Dependent Resident Myonuclear Multi-Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice, Pieter J. Koopmans, Ronald G. Jones, Ana Regina Cabrera, Francielly Morena, Nicholas P. Greene, John J. McCarthy, Ahmed Ismaeel, Yuan Wen, and Kevin A. Murach
Human atrial skinned muscle fibers exhibit reduced length-dependent activation but show faster force development kinetics than ventricular muscle, Alexandre Lewalle, Gregory Milburn, Jania Bell, Kenneth S. Campbell, and Steven A. Niederer
A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia, Farzaneh S. Mirfakhar, Jacob A. Marsh, Chihiro Sato, Kylie J. Schache, Miguel A. Minaya, Roland E. Dolle, Stephen C. Pak, Gary A. Silverman, David H. Perlmutter, Shannon L. Macauley, and Celeste M. Karch
Evidence of interparticle chylomicron “bridging” in mouse mesenteric lymph after a lipid bolus, Khaga Raj Neupane, Alexander Karakashian, Min Liu, and Scott M. Gordon
DENND5B disruption results in reduced body fat and increased intestinal fatty acid oxidation by activation of autophagy, Khaga R. Neupane, Alexander Karakashian, Maura Mobilia, Olivia Hage, Patrick Tso, Min Liu, Laurent Vergnes, Karen Reue, and Scott M. Gordon
Dim light at night worsens cardiac autonomic dysregulation in female diabetic mice, Abhilash Prabhat, Shrishti Naidu, Isabel G. Stumpf, Tanya S. Seward, Elizabeth A. Schroder, and Brian P. Delisle
Mass Spectrometry-Based Spatial Imaging of the Cochlea, Roberto A. Ribas, Qun Tang, Scarlett I. Caffee, Cameron J. Shedlock, Tara R. Hawkinson, Abigail K. Dragich, Borhane E.C. Ziani, Franca Bucco Paolasso, Alyson P. Black, Xin Ma, Harshitha C. Kota, Li Chen, Gregory I. Frolenkov, Derek B. Allison, Matthew S. Gentry, Ramon C. Sun, and Craig W. Vander Kooi
Neutralization of reactive oxygen species with cobinamide augments aortic dissections and rupture in BAPN-administered mice, Alexis Richard, Zhen Zhou, Jose Emiliano Esparza Pinelo, Callie S. Kwartler, Hema Kalyanaraman, Gerry R. Boss, Hong S. Lu, Alan Daugherty, and Dianna M. Milewicz
Thyroid hormone augmentation accelerates hair cell maturation in human cochlear organoids, Tsubasa Saeki, Yoshitomo Ueda, Isabel Aristizábal-Ramírez, Stephen T. Moore, Rick F. Nelson, Gregory I. Frolenkov, and Eri Hashino
From lipoprotein metabolism to blood clotting, Alexis N. Smith, Mirza A. Beg, Woosuk Steve Hur, David Ginsburg, Iftikhar J. Kullo, Sean S. Davies, Ira Tabas, Jesse W. Williams, Chieko Mineo, Bishuang Cai, Rana K. Gupta, Jaume Amengual, Anna Schwendeman, Gregory A. Graf, Mary Sorci Thomas, and Ze Zheng
Spatial control of myosin regulatory light chain phosphorylation modulates cardiac thick filament mechanosensing, Caterina Squarci, Daniel Koch, Paul Anaya, Kenneth S. Campbell, and Thomas Kampourakis
Cytoprotective role of octacosanol in lipopolysaccharide-induced inflammation, Jingrong Tang, Zhi Hong Yang, Wenling Li, Huaitian Liu, Diego Lucero, Denis Sviridov, Olivia White, Julia Kun, Yoh Suke Mukouyama, and Alan T. Remaley
Exercise training prior to and during cancer in mice preserves muscle mass, reduces tumour weight and suppresses molecular mediators of cachexia, Stavroula Tsitkanou, Pieter J. Koopmans, Ana Regina Cabrera, Nathan Serrano, Calvin S. Peterson, Ruqaiza Muhyudin, Zain B. Malik, Micah Goeke, Eleanor R. Schrems, Francielly Morena, Yuan Wen, Tyrone A. Washington, Kevin A. Murach, and Nicholas P. Greene
Use of function diagrams in physiology education, Thad E. Wilson, Brian A. Jackson, and B. Peter Sawaya
