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Theses and Dissertations--Pharmacy

Theses/Dissertations from 2020 2020

Relationship Between Initial Prescription Opioid Exposure Length and Future Opioid Use Disorder Diagnosis in Opioid Naive Adolescents, Eric Lindahl

Characterization and Engineering of Interrupted Adenylation Domains, Taylor A. Lundy

Meaningful Measurement Matters: Defining Potentially Inappropriate Medication Use to Target Cognitive Outcomes, Ashley I. Martinez

ANTIRESORPTIVE BONE THERAPY USE IN ADVANCED LUNG CANCER AND ASSOCIATED OUTCOMES, Noor Naffakh

POPULATION PHARMACOKINETIC MODELING AND GENETIC ASSOCIATION ANALYSIS IN INFANTS WITH NEONATAL ABSTINENCE SYNDROME RECEIVING MORPHINE OR CLONIDINE, Fei Tang

Theses/Dissertations from 2019 2019

DEVELOPMENT OF MITHRAMYCIN ANALOGUES WITH IMPROVED EFFICACY AND REDUCED TOXICITY FOR TREATMENT OF ETS-DEPENDENT TUMORS IN EWING SARCOMA AND PROSTATE CANCER, Joseph Michael Eckenrode

MECHANISMS AND THERMODYNAMICS OF THE INFLUENCE OF SOLUTION-STATE INTERACTIONS BETWEEN HPMC AND SURFACTANTS ON MIXED ADSORPTION ONTO MODEL NANOPARTICLES, Salin Gupta Patel

DEVELOPING A WORKFLOW TO EVALUATE MEDICATIONS FOR REPURPOSING USING HEALTH CLAIMS DATA: APPLICATION TO SUBSTANCE USE DISORDERS, Emily Ruth Hankosky

TOWARD AN ENZYME-COUPLED, BIOORTHOGONAL PLATFORM FOR METHYLTRANSFERASES: PROBING THE SPECIFICITY OF METHIONINE ADENOSYLTRANSFERASES, Tyler D. Huber

CARBAPENEM-RESISTANT ENTEROBACTERIACEAE: EPIDEMIOLOGY, GENETICS, IN VITRO ACTIVITY, AND PHARMACODYNAMIC MODELING, Brandon Kulengowski

INVESTIGATION OF FACTORS INFLUENCING PROTEIN STABILITY IN LYOPHILIZED FORMULATIONS USING SOLID-STATE NMR SPECTROSCOPY, Ashley Lay-Fortenbery

THE DEVELOPMENT OF NOVEL PROTEASOME INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA AND ALZHEIMER’S DISEASE, Min Jae Lee

DISCOVERY OF NOVEL PHARMACOTHERAPEUTICS FOR SUBSTANCE USE DISORDERS, Na-Ra Lee

ACTINOMYCIN FAMILIAL DIVERSITY DRIVEN BY PHENOXAZINONE-CORE REACTIVITY, Matthew Richard McErlean

PHASE BEHAVIOR OF AMORPHOUS SOLID DISPERSIONS: MISCIBILITY AND MOLECULAR INTERACTIONS, Kanika Sarpal

Trends and Patterns in Use of Medications for Opioid Use Disorder in a Commercially Insured Population in the U.S., Catherine Serratore

THERAPEUTIC VIDEO GAMES AND THE SIMULATION OF EXECUTIVE FUNCTION DEFICITS IN ADHD, Markus Tiitto

Pharmacokinetic and Pharmacodynamic Evaluation of Cocaine Hydrolases for the Treatment of Cocaine Overdose and Cocaine Addiction Using Rodent Models, Xirong Zheng

COMPUTATIONAL MODELING GUIDED DISCOVERY OF NOVEL INHIBITORS OF MPGES-1 AND BUTYRYLCHOLINESTERASE AS DRUG CANDIDATES, Shuo Zhou

Theses/Dissertations from 2018 2018

DISCOVERY OF NOVEL MURAYMYCIN ANTIBIOTICS AND INSIGHT INTO THE BIOSYNTHETIC PATHWAY, Zheng Cui

USING THE QBEST EQUATION TO EVALUATE ELLAGIC ACID SAFETY DATA: GENERATING A QNOAEL WITH CONFIDENCE LEVELS FROM DISPARATE LITERATURE, Cynthia Rose Dickerson

EXPLORING THE EFFECT OF CHRONIC INFLAMMATION ON RESPONSE TO IMMUNE CHECKPOINT INHIBITORS IN CANCER, Sherif M. El-Refai

ALTERNATIVELY ACTIVATED MACROPHAGES IN PSEUDOMONAS AERUGINOSA PNEUMONIA: MODULATION OF THE NF-ΚB SIGNALING PATHWAY AND THE IMMUNOMODULATORY ROLE OF ARGINASE-1, Dalia Haydar

DISCOVERY OF NEW ANTIMICROBIAL OPTIONS AND EVALUATION OF AMINOGLYCOSIDE RESISTANCE ENZYME-ASSOCIATED RESISTANCE EPIDEMIC, Selina Y. L. Holbrook

CHARACTERIZATION AND ENGINEERING OF HUMAN PROTEINS AS THERAPEUTIC CANDIDATES, Kyungbo Kim