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Theses/Dissertations from 2024

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Investigating a New Drug Target in Alzheimer’s Disease: NOX2, Tiffany Adams

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Design of Kappa Opioid Receptor Agonists for Potential Treatment of Multiple Sclerosis, Lindsay Kornberger

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Sensitizing KEAP1 loss non-small cell lung cancer to artesunate anti-cancer activity, Keng Hee Peh

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INHIBITING PI3K/AKT TO ENHANCE BRAIN UPTAKE OF ANTICANCER AGENTS IN GLIOBLASTOMA, Louis Rodgers

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NEUROIMMUNE RESPONSE AND NEURODEGENERATION IN ADOLESCENT RATS FOLLOWING BINGE ALCOHOL EXPOSURE, Catherine Van Doorn

Theses/Dissertations from 2023

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Self-Assembled Ternary Polypeptide Nanoparticles With Improved Biostability For Drug Delivery In Cancer Therapy, Preye Mike Agbana

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Investigation of Folate-Poly(Glutamic Acid)/Polyethylenimine/DNA Complexes for in vitro Gene Delivery, Caleb Akers

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POPULATION-BASED EVALUATION OF TREATMENT PATTERNS, DRUG-DRUG INTERACTIONS, AND CARDIOVASCULAR RISK IN PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER, Yue Cheng

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An Epidemiological and Pharmacokinetic-pharmacodynamic Investigation into the Impact of Carbapenem-resistant Enterobacterales, Justin Clark

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STRIVING FOR APPROPRIATE ANTIBIOTIC USE: A BIOMARKER INITIATIVE, AND OUTCOMES ASSOCIATED WITH AZITHROMYCIN EXPOSURE, Amanda Gusovsky

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New Tools for Biocatalysis: Studies on the Carminomycin 4-O-Methyltransferase DnrK, Elnaz Jalali

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Optimization of Orally Bioavailable Inhibitors of Defective in Cullin Neddylation 1 (DCN-1), Leah Kovalic

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Genetic and Pharmacogenetics Associations of Cancer Disparities in Appalachia, Nan Lin

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Design and Synthesis of Small Molecular Inhibitors of DCN1-UBE2M Interaction, Tucker J. Moseley

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Effectiveness of a long-acting cocaine hydrolase in metabolizing cocaine and its physiologically active metabolites, Linyue Shang

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Anti-Inflammatory and Analgesic Effects of Highly Selective Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors, Madeline Stewart

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INVESTIGATING THE USE OF mPGES-1 INHIBITORS FOR THE TREATMENT OF ABDOMINAL AORTIC ANEURYSMS, Lauren M. Weaver

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DEVELOPING A BIOCATALYTIC TOOLBOX TO AID IN UNDERSTANDING NUCLEOSIDE ANTIBIOTICS, Jasmine Brianna Woods

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BIOINFORMATIC ANALYSIS OF PROTEOMIC AND GENOMIC DATA FROM NSCLC TUMORS ON PROGNOSTIC AND PREDICTIVE FACTORS OF IMMUNOTHERAPY TREATMENT, Mark Wuenschel

Theses/Dissertations from 2022

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Response of Dopaminergic System to Cocaine Exposure, Recovery after Cocaine Abstinence, and Impact of a Long-acting Cocaine Hydrolase, Jing Deng

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ANALYSIS OF POTENTIAL FACILITATORS TO USE OF HIV PRE-EXPOSURE PROPHYLAXIS (PrEP) IN A YOUNG TRANSGENDER POPULATION, Noah Dixon

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Studies Toward the Development of an Improved Countermeasure for Synthetic Opioid Overdose, Sidnee L. Hedrick

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Development of zafirlukast derivatives active against Porphyromonas gingivalis, Kaitlind C. Howard

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Investigating the Physical Stability of Amorphous Pharmaceutical Formulations, Travis W. Jarrells

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THE RELATIVE CONTRIBUTION OF LIVER AND INTESTINE IN REVERSE CHOLESTEROL TRANSPORT, Rupinder Kaur