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Submissions from 2024

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Type-2 Diabetes, Pancreatic Amylin, and Neuronal Metabolic Remodeling in Alzheimer's Disease, Noah Leibold, James R. Bain, and Florin Despa

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Enlarged perivascular space burden predicts declines in cognitive and functional performance, Timothy Justin Libecap, Colleen A. Pappas, Christopher E. Bauer, Valentinos Zachariou, Flavius D. Raslau, and Brian T. Gold

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Cerebrovascular reactivity MRI as a biomarker for cerebral small vessel disease–related cognitive decline: Multi-site validation in the MarkVCID Consortium, Peiying Liu, Zixuan Lin, Kaisha Hazel, George Pottanat, Cuimei Xu, Dengrong Jiang, Jay J. Pillai, Emma Lucke, Christopher E. Bauer, Brian T. Gold, Steven M. Greenburg, Karl G. Helmer, Kay Jann, Gregory Jicha, Joel Kramer, Pauline Maillard, Rachel M. Mulavelil, Pavel Rodriguez, Claudia L. Satizabal, Kristin Schwab, Sudha Seshadri, Herpreet Singh, Ángel G. Velarde Dediós, Danny J. J. Wang, Rita R. Kalyani, Abhay Moghekar, Paul B. Rosenberg, Sevil Yasar, Marilyn Albert, and Hanzhang Lu

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Myosin XVA isoforms participate in the mechanotransduction-dependent remodeling of the actin cytoskeleton in auditory stereocilia, Ana I. López-Porras, Ava M. Kruse, Mark T. McClendon, and A. Catalina Vélez-Ortega

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National Trends of Vascular Risk Factor Control Among Stroke Survivors: From the National Health and Nutrition Examination Survey 2009 to 2020, Hend Mansoor, Daniel Manion, Kara Jo Swafford, Gregory A. Jicha, and Daniela Claudia Moga

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HIV-1 mRNA knockdown with CRISPR/CAS9 enhances neurocognitive function, Kristen A. McLaurin, Hailong Li, Kamel Khalili, Charles F. Mactutus, and Rosemarie M. Booze

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The differential proteomic response to ischemic stroke in appalachian subjects treated with mechanical thrombectomy, Christopher J. McLouth, Benton Maglinger, Jacqueline A. Frank, Kristin J. Hazelwood, Jordan P. Harp, Will Cranford, Shivani Pahwa, David Dornbos III, Amanda L. Trout, Ann M. Stowe, Justin F. Fraser, and Keith R. Pennypacker

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Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC): Co-pathologies and genetic risk factors provide clues about pathogenesis, Peter T. Nelson, David Fardo, Xian Wu, Khine Zin Aung, Matthew D. Cykowski, and Yuriko Katsumata

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Using digital pathology to analyze the murine cerebrovasculature, Dana M. Niedowicz, Jenna L. Gollihue, Erica M. Weekman, Panhavuth Phe, Donna M. Wilcock, Christopher M. Norris, and Peter T. Nelson

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Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort, Takaki Oka, Yuki Matsuzawa, Momoka Tsuneyoshi, Yoshitaka Nakamura, Ken Aoshima, Hiroshi Tsugawa, and Alzheimer’s Disease Metabolomics Consortium

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The role of a dental healthcare provider, Jeffrey P. Okeson

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Azithromycin reduces hemoglobin-induced innate neuroimmune activation, Chirayu D. Pandya, Hemendra J. Vekaria, Miriam Zamorano, Amanda L. Trout, Rodney M. Ritzel, Gary Guzman, Christopher Bolden, and Patrick G. Sullivan

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Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS, Tess D. Pottinger, Joshua E. Motelow, Gundula Povysil, Cristiane A. Martins Moreno, Zhong Ren, Hemali Phatnani, The New York Genome Center ALS Sequencing Consortium, Timothy J. Aitman, Javier Santoyo‑Lopez, Scottish Genomes Partnership, Hiroshi Mitsumoto, ALS COSMOS Study Group, PLS COSMOS Study Group, GTAC Investigators, David B. Goldstein, and Matthew B. Harms

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A brief report on juvenile amyotrophic lateral sclerosis cases in the United States National ALS Registry: 2010– 2018, Jaime Raymond, Jasmine Berry, Edward J. Kasarskis, Theodore Larson, D. Kevin Horton, and Paul Mehta

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Estimating Socio-Economic Status for Alzheimer’s Disease Trials, D. M. Rentz, J. D. Grill, D. P. Molina-Henry, Gregory Jicha, Michael S. Rafii, A. Liu, Reisa A. Sperling, Paul Aisen, and R. Raman

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Frequency of low ImPACT scores among adolescent and young adult student-athletes with attention-deficit/hyperactivity disorder and/or learning disorder, Philip Schatz, John Cuzzupe, Justin E. Karr, Nathan E. Cook, and Grant L. Iverson

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The Seattle Amyotrophic Lateral Sclerosis (ALS) Patient Project Database: observational, longitudinal, dyadic characterization of people with ALS and their partners, Suzanne C. Segerstrom and Edward J. Kasarskis

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A pathologic study of Perivascular pTDP-43 Lin bodies in LATE-NC, Ryan K. Shahidehpour, Peter T. Nelson, and Adam D. Bachstetter

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Astrocytic stress response is induced by exposure to astrocyte-binding antibodies expressed by plasmablasts from pediatric patients with acute transverse myelitis, Chad Smith, Kiel M. Telesford, Sara G. M. Piccirillo, Yamhilette Licon‑Munoz, Wei Zhang, Key M. Tse, Jacqueline R. Rivas, Chaitanya Joshi, Dilan S. Shah, Angela X. Wu, Ritu Trivedi, Scott Christley, Yu Qian, Lindsay G. Cowell, Richard H. Scheuermann, Ann M. Stowe, Linda Nguyen, Benjamin M. Greenberg, and Nancy L. Monson

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Axonal injury, sleep disturbances, and memory following traumatic brain injury, Emma M. Tinney, Goretti España-Irla, Aaron E. L. Warren, Lauren N. Whitehurst, Alexandra N. Stillman, Charles H. Hillman, Timothy P. Morris, and Alzheimer’s Disease Neuroimaging Initiative

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Estrogen’s sex-specific effects on ischemic cell death and estrogen receptor mRNA expression in rat cortical organotypic explants, Amanda L. Trout, Christopher J. McLouth, Jenna Westberry, Tomoko Sengoku, and Melinda E. Wilson

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Targeted long-read sequencing to quantify methylation of the C9orf72 repeat expansion, Evan Udine, NiCole Finch, Mariely DeJesus-Hernandez, Jazmyne L. Jackson, Matthew C. Baker, Siva Arumugam Saravanaperumal, Eric Wieben, Mark T. W. Ebbert, Jaimin Shah, Leonard Petrucelli, Rosa Rademakers, Björn Oskarsson, and Marka van Blitterswijk

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Astrocytic mitochondrial transfer to brain endothelial cells and pericytes in vivo increases with aging, Gopal V. Velmurugan, Hemendra J. Vekaria, Samir P. Patel, Patrick G. Sullivan, and W. Brad Hubbard

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The AlzMatch Pilot Study - Feasibility of Remote Blood Collection of Plasma Biomarkers for Preclinical Alzheimer’s Disease Trials, S. Walter, O. Langford, G. A. Jimenez-Maggiora, S. Abdel-Latif, R. A. Rissman, J. D. Grill, J. Karlawish, A. Atri, S. Bruschi, K. Hussen, M. C. Donohue, G. A. Marshall, Gregory Jicha, M. Racke, R. S. Turner, C. H. van Dyck, V. Venkatesh, K. E. Yarasheski, R. Sperling, J. Cummings, Paul Aisen, and R. Raman

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Comprehensive assessment of TDP‑43 neuropathology data in the National Alzheimer’s Coordinating Center database, Davis C. Woodworth, Katelynn M. Nguyen, Lorena Sordo, Kiana A. Scambray, Elizabeth Head, Claudia H. Kawas, María M. Corrada, Peter T. Nelson, and S. Ahmad Sajjadi