Submissions from 2026
The association between APOE ε4 carrierships and the detection of amyloid positivity using an Alzheimer's disease proteomic blood test in asymptomatic Down syndrome, Lubnaa Badriyyah Abdullah, Fan Zhang, Melissa Petersen, James Hall, Benjamin L. Handen, Mark Mapstone, Brad Christian, Elizabeth Head, Sigan Harley, Howard Andrews, Joseph H. Lee, Dana Tudorascu, Christy Hom, Shahid Zaman, Adam M. Brickman, Diana Rosas, Annie Cohen, Jordan P. Harp, Frederick Schmitt, Lauren Ptomey, Jeffrey M. Burns, Ira T. Lott, Florence Lai, Charles Laymon, Carlos Cruchaga, Sid O'Bryant, and Beau M. Ances
Provider and patient perspectives on the diagnosis and treatment of Alzheimer's disease, Philippe Amouyel, Sandrine Andrieu, Angela Bradshaw, Ralph C. Carmona, Magali Dumont, Lea Tenenholz Grinberg, Takeshi Iwatsubo, Oskar Hansson, Clifford R. Jack, Gregory A. Jicha, Simin Mahinrad, Eric McDade, Catherine J. Mummery, Ronald C. Petersen, Shelagh Robinson, Julie A. Schneider, Lenny Shellcross, Amanda G. Smith, Heather M. Snyder, Beth Tapply, Charlotte Teunissen, Wiesje M. van der Flier, Bruno Vellas, David Wallon, Jeff D. Williamson, Donna Wilcock, and Maria C. Carrillo
Frontal Release Signs and Future Decline in Research Participants With Intact Cognition, Lauren G. Bojarski, Gregory A. Jicha, Elif Pinar Coskun, Frederick A. Schmitt, Linda Van Eldik, and Erin L. Abner
Using clinical and thrombus characteristics to predict the etiology of ischemic stroke, Graham A. Branscom, Carina Seah, Tannishtha Som, James Vicari, Alan R. Dabney, Selva Baltan, Farida Sohrabji, Keith Pennypacker, Keith B. Woodward, Benjamin I. Rapoport, Sol Schulman, Justin F. Fraser, and Christopher P. Kellner
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegeneration, Nikhil N. Chaudhari, Owen M. Vega, Phoebe Imms, Jaron M. Kawamura, Nahian F. Chowdhury, Tamara Jafar, Andrei Irimia, Kenneth Spicer, Crystal Flynn Longmire, Jacobo Mintzer, Yaneicy Gonazalez Rojas, V. Sotelo, William Hu, Floyd Jones, Amy Saklad, Sudha Seshadri, Amy Boegel, Sydni Jenee Hill, Paul Newhouse, Rebecca Long, Campbell Long, Arthur Williams, Allison Acree, Olga Brawman-Mintzer, Chelsea Reichert, Vita Pomara, Raymundo Hernando, Nunzio Pomara, Skieff Acothley, Nadeen Elayan, and Micah Ellis Slaughter
The impact of congenital heart disease on the timing of Alzheimer's disease in Down syndrome, Julianne G. Clina, Brian C. Helsel, Sigan L. Hartley, David A. White, Victoria L. Fleming-Batayneh, Benjamin Handen, Bradley Christian, Elizabeth Head, Mark Mapstone, Christy L. Hom, Beau Ances, Jeffrey Burns, H. Diana Rosas, Florence Lai, Sharon Krinsky McHale, Joseph H. Lee, Frederick A. Schmitt, Jordan Harp, Ira T. Lott, Shahid Zaman, and Lauren T. Ptomey
Peripheral amylin modulation rebalances brain glycolysis and Tau-Ser214 phosphorylation via cAMP-PKA signaling, Ravichandra S. Davargaon, Nirmal Verma, Deepak Kotiya, Noah Leibold, Gopal Viswanathan Velmurugan, Han Coburn, Kuey C. Chen, Daniel Ruiz, Victor Corces, Huazhen Liu, Pradeep Kachroo, Pankaj K. Singh, Matthew S. Gentry, Sanda Despa, and Florin Despa
Decoding the human PBMC isonome, Patricia Hayes Doyle, Madeline L. Page, J. Anthony Brandon, Bernardo Aguzzoli Heberle, Brendan J. White, Ann Marie Stowe, and Mark T.W. Ebbert
Postapproval Study for Brain-Responsive Neurostimulation for Drug-Resistant Focal Epilepsy, Dawn Eliashiv, Vikram R. Rao, Barbara C. Jobst, Jerzy P. Szaflarski, John D. Rolston, Lesley C. Kaye, Taneeta Mindy Ganguly, Katie Bullinger, Patricia C. Dugan, David E. Burdette, Angela Y. Peters, Atif Sheikh, Kevin F. Haas, Dileep R. Nair, Lilit Mnatsakanyan, Imran H. Quraishi, Meriem K. Bensalem-Owen, Michael J. Doherty, Babak Razavi, Tiffany L. Fisher, Christopher Skidmore, Pradeep N. Modur, Tawnya M. Constantino, Vicenta Salanova, Andrew J. Cole, Olga Taraschenko, Angelica Rivera-Cruz, James W. Wheless, Nitin Tandon, Antoaneta Balabanov, and Sami Aboumatar
Inflammation Associated With Obesity, Aging, and Amyloid Burden in Adults With Down Syndrome, Victoria L. Fleming-Batayneh, Brian C. Helsel, Lauren T. Ptomey, Benjamin L. Handen, Mark Mapstone, Melissa Petersen, Sharon J. Krinsky-McHale, Christy L. Hom, Davneet Minhas, Weiquan Luo, Charles Laymon, Joseph H. Lee, Annie Cohen, Beau M. Ances, Adam M. Brickman, Margaret Pulsifer, H. Diana Rosas, Florencia Lai, Shahid H. Zaman, Elizabeth Head, Dana Tudorascu, Julie Price, Fredrick Schmitt, Bradley T. Christian, Ozioma Okonkwo, Sigan L. Hartley, Beau M. Ances, Howard F. Andrews, Karen Bell, Rasmus M. Birn, and Adam M. Brickman
Frequency of mixed neuropathologies in individuals with down syndrome with and without Alzheimer's dementia, Lisi Flores-Aguilar, Thomas D. Zaikos, Isabel Rivera, Sierra T. Wright, Jerry Lou, Brianna Gawronski, Lourdes Gonzalez, Jillian V. Berry, Jeremy Rouanet, Natalie C. Edwards, Dan K. Hoang, Kevin Wood, Ann Charlotte Granholm, Elliott J. Mufson, Edwin S. Monuki, Milos D. Ikonomovic, Julia Kofler, Eric W. Doran, Ira T. Lott, Minodora O. Totoiu, Christy L. Hom, Florence Lai, William H. Yong, Frederick Schmitt, Jordan Harp, Peter T. Nelson, Jose Gutierrez, Patrick J. Lao, Donna Wilcock, Adam M. Brickman, and Elizabeth Head
Post-approval study 3-year outcomes of the Neuroform Atlas stent for the treatment of wide-necked intracranial aneurysms, Brian Jankowitz, Ashutosh P. Jadhav, Bradley Gross, Tudor G. Jovin, Abdulnasser A. Alhajeri, Justin F. Fraser, Ricardo A. Hanel, Eric Sauvageau, Amin Aghaebrahim, Donald Frei, Richard Bellon, David N. Loy, Ajit S. Puri, Adel M. Malek, Ajith J. Thomas, Gabor Toth, Demetrius Klee Lopes, R. Webster Crowley, John Reavey-Cantwell, Eugene Lin, Adnan Siddiqui, Michael J. Alexander, Ahmad Khaldi, Geoffrey P. Colby, Justin M. Caplan, Sudhakar R. Satti, Aquilla S. Turk, Alejandro M. Spiotta, Richard Klucznik, Danial K. Hallam, David Kung, and Michael T. Froehler
Hyperacute Interleukin-1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion, Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, and Eva Tolosa
Neuropathological measures of increased tau phosphorylation across the Down syndrome lifespan, Jesse R. Pascual, Isabel Rivera, Halyma Nguyen, Phong T. Ngo, Alan Hoang, Elizabeth J. Andrews, Jeremy Rouanet, Sierra T. Wright, Lorena Sordo, Julia Kofler, Milos D. Ikonomovic, Florence Lai, Mark Mapstone, Bradley T. Christian, Benjamin L. Handen, Ira T. Lott, Eric Doran, Christy L. Hom, Jordan Harp, Frederick Schmitt, Dana L. Tudorascu, Beau M. Ances, Michael Phelan, Lei Liu, Lisi Flores-Aguilar, Elizabeth Head, Fan Zhang, Shahid Zaman, Michael A. Yassa, Badri Varadarajan, and Rameshwari Tumuluru
Plasma p-tau217 and APOE genotype, Ann M. Stowe, Bilal Kahn, Ali Ballesteros, Monique Cortez, Linda S. Hynan, Victoria Cantrell, Indu Raman, Guangchun Chen, Eric D. Vidoni, Ellen Binder, Jeffrey Burns, Jeffrey N. Keller, Diana R. Kerwin, Tristyn Hall, Pavel Yanev, Wanpen Vongapatanasin, David C. Zhu, Norman Scheel, C. Munro Cullum, Rong Zhang, and Dwight C. German
Phase 1 open-label study of ASP9801, an oncolytic virus, in patients with advanced or metastatic solid tumors, John L. Villano, Jason J. Luke, Ricklie Julian, Christos Fountzilas, Manish R. Patel, Michael J. Chisamore, Pranob Bhattacharya, Shigeru Takeshita, Serguei Soukharev, Shunsuke Yamada, Leshi Zhang, and Kristopher P. Wentzel
Hyaluronan 35 prevents endotoxin-mediated dysregulated skeletal muscle proteostasis during ethanol exposure, Nicole Welch, Pugazhendhi Kannan, Gangarao Davuluri, Annette Bellar, Amy H. Attaway, Saurabh Mishra, Jasmin A. Cunningham, Avinash Kumar, Ryan Musich, Elif G. Ertugral, Vandana Agrawal, Isaac L. Hsu, Terri J. Harford, Noah L. Weisleder, Vidula T. Vachharajani, Chandrasekhar R. Kothapalli, Carol A. de la Motte, Laura E. Nagy, and Srinivasan Dasarathy
Impact of COVID-19 positive status on outcome for individuals with stroke treated in acute inpatient rehabilitation, Amy Ziems, Christopher J. McLouth, Nicholas Elwert, Elissa Charbonneau, Joseph Stillo, and Susan McDowell
Submissions from 2025
A 40-week phase 2B randomized, multicenter, double-blind, placebo-controlled study evaluating the safety and efficacy of memantine in amyotrophic lateral sclerosis, Salman Bhai, Todd Levine, Dan Moore, Robert Bowser, Andrew J. Heim, Maureen Walsh, Aziz Shibani, Zachary Simmons, James Grogan, Namita A. Goyal, Raghav Govindarajan, Yessar Hussain, Tania Papsdorf, Tiffany Schwasinger-Schmidt, Nick Olney, Kim Goslin, Michael Pulley, Edward J. Kasarskis, Michael Weiss, Susan W. Katz, Suzan Moser, Duaa Jabari, Omar Jawdat, Jeffrey Statland, Mazen M. Dimachkie, Richard Barohn, and Neuromuscular Study Group and Western ALS Consortium Memantine ALS Study Group
Amyloid-β predominant Alzheimer’s disease neuropathologic change, Gabor G. Kovacs, Yuriko Katsumata, Xian Wu, Khine Zin Aung, David Fardo, Shelley L. Forrest, and Peter T. Nelson
Interaction between riluzole treatment and dietary glycemic index in the disease progression of amyotrophic lateral sclerosis, Ikjae Lee, Hiroshi Mitsumoto, Seonjoo Lee, Edward J. Kasarskis, Michael Rosenbaum, Pam Factor-Litvak, and Jeri W. Nieves
Synergistic effects of plasma S100B and MRI measures of cerebrovascular disease on cognition in older adults, Colleen A. Pappas, Christopher E. Bauer, Valentinos Zachariou, Timothy Justin Libecap, Beatriz Rodolpho, Tiffany L. Sudduth, Peter T. Nelson, Gregory Jicha, Anika M. S. Hartz, Xingfeng Shao, Danny J. J. Wang, and Brian T. Gold
Blood biomarkers in Down syndrome: Facilitating Alzheimer’s disease detection and monitoring, Melissa E. Petersen, Lisi Flores-Aguilar, Elizabeth Head, Laia Montoliu-Gaya, Andre Strydom, Sarah E. Pape, Juan Fortea, Nicholas J. Ashton, Chinedu Udeh-Momoh, Sid E. O’Bryant, Dwight German, Florin Despa, Mark Mapstone, and Henrik Zetterberg
Data reporting quality and semantic interoperability increase with community-based data elements (CoDEs). Analysis of the open data commons for spinal cord injury (ODC-SCI), Anushka Sheoran, Kenneth A. Fond, Lex Maliga Davis, J. R. Huie, Romana Vavrek, P. J. Axtman, Vance P. Lemmon, John L. Bixby, Ubbo Visser, John C. Gensel, Karim Fouad, Adam R. Ferguson, Jeffrey S. Grethe, Anita Bandrowski, Maryann E. Martone, and Abel Torres-Espin
Cognitive Rehabilitation of Brain Tumor Survivors: A Systematic Review, Rabeet Tariq, Hafiza Fatima Aziz, Shahier Paracha, Nida Zahid, Timothy J. Ainger, Farhan A. Mirza, and Syed Ather Enam
