This collection was named as Graduate Center for Toxicology Faculty Publications before Jan. 1, 2015.

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Submissions from 2018

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Preclinical Evaluation of Novel Fatty Acid Synthase Inhibitors in Primary Colorectal Cancer Cells and a Patient-Derived Xenograft Model of Colorectal Cancer, Yekaterina Y. Zaytseva, Piotr G. Rychahou, Anh-Thu Le, Timothy L. Scott, Robert M. Flight, Ji Tae Kim, Jennifer Harris, Jinpeng Liu, Chi Wang, Andrew J. Morris, Theru A. Sivakumaran, Teresa Fan, Hunter Moseley, Tianyan Gao, Eun Young Lee, Heidi L. Weiss, Timothy S. Heuer, George Kemble, and B. Mark Evers

Submissions from 2017

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Exploring Cancer Metabolism Using Stable Isotope-Resolved Metabolomics (SIRM), Ronald C. Bruntz, Andrew N. Lane, Richard M. Higashi, and Teresa W. -M. Fan

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Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis, Ravshan Burikhanov, Nikhil Hebbar, Sunil K. Noothi, Nidhi Shukla, James Sledziona, Nathália Araujo, Meghana Kudrimoti, Qing Jun Wang, David S. Watt, Danny R. Welch, Jodi Maranchie, Akihiro Harada, and Vivek M. Rangnekar

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Reversion of Epithelial-Mesenchymal Transition by a Novel Agent DZ-50 via IGF Binding Protein-3 in Prostate Cancer Cells, Zheng Cao, Shahriar Koochekpour, Stephen E. Strup, and Natasha Kyprianou

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M2 Polarization of Macrophages Facilitates Arsenic-Induced Cell Transformation of Lung Epithelial Cells, Jiajun Cui, Wenhua Xu, Jian Chen, Hui Li, Lu Dai, Jacqueline A. Frank, Shaojun Peng, Siying Wang, and Gang Chen

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Loss of Fructose-1,6-Bisphosphatase Induces Glycolysis and Promotes Apoptosis Resistance of Cancer Stem-Like Cells: An Important Role in Hexavalent Chromium-Induced Carcinogenesis, Jin Dai, Yanli Ji, Wei Wang, Donghern Kim, Leonard Yenwong Fai, Lei Wang, Jia Luo, and Zhuo Zhang

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Out in the Cold: Ingredients in Over-the-Counter Cold Medicines Can Wreak Havod on a Trainer's Livelihood and an Owner's Prized Racehorse, Clara Fenger, Tanya Boulmetis, and Thomas Tobin

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An In-Depth Look at Stall Contamination: A Total of 28 Substances Were Identified in Charles Town Ship-In Stalls as a Mix of Human Medications and Recreational Substances with Some Actual Equine Medications, Clara Fenger, Maria Catignani, Jake Machin, and Thomas Tobin

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Medication Migration: The Charles Town Naproxen Experience and Why It Matters to All Racing Jurisdictions, Clara Fenger and Thomas Tobin

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No Lasix Racing: Good Idea or Failed Experiment?, Clara Fenger, Thomas Tobin, and Peter Ecabert

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Effect of Cigarette Smoke Exposure and Mutant Kras Overexpression on Pancreatic Cell Proliferation, Howard P. Glauert, R. Scott Elliott, Sung Gu Han, Mark Athey, Eun Young Lee, and C. Gary Gairola

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Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles, Sijin Guo, Hui Li, Mengshi Ma, Jian Fu, Yizhou Dong, and Peixuan Guo

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A Naturally Generated Decoy of the Prostate Apoptosis Response-4 Protein Overcomes Therapy Resistance in Tumors, Nikhil Hebbar, Ravshan Burikhanov, Nidhi Shukla, Shirley Qiu, Yanming Zhao, Kojo S. J. Elenitoba-Johnson, and Vivek M. Rangnekar

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Nuclear Spindles Pave the Way to Metastasis, Patrick J. Hensley and Natasha Kyprianou

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Abl Kinase Regulation by BRAF/ERK and Cooperation with Akt in Melanoma, Aditi Jain, Rakshamani Tripathi, Courtney P. Turpin, Chi Wang, and Rina Plattner

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Melatonin and Its Metabolites Protect Human Melanocytes Against UVB-Induced Damage: Involvement of NRF2-Mediated Pathways, Zorica Janjetovic, Stuart G. Jarrett, Elizabeth F. Lee, Cory Duprey, Russel J. Reiter, and Andrzej T. Slominski

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Paracrine Regulation of Melanocyte Genomic Stability: A Focus on Nucleotide Excision Repair, Stuart Gordon Jarrett, Katharine Marie Carter, and John August D'Orazio

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MutSβ Abundance and Msh3 ATP Hydrolysis Activity Are Important Drivers of CTG•CAG Repeat Expansions, Norma Keogh, Kara Y. Chan, Guo-Min Li, and Robert S. Lahue

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Clinical and Experimental Studies of a Novel P525R FUS Mutation in Amyotrophic Lateral Sclerosis, Lisha Kuang, Marisa Kamelgarn, Alexandra Arenas, Jozsef Gal, Deborah Taylor, Weiming Gong, Martin Brown, Daret St. Clair, Edward J. Kasarskis, and Haining Zhu

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Probing the Metabolic Phenotype of Breast Cancer Cells by Multiple Tracer Stable Isotope Resolved Metabolomics, Andrew N. Lane, Julie Tan, Yali Wang, Jun Yan, Richard M. Higashi, and Teresa W. -M. Fan

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Increased ROS Production in Non-Polarized Mammary Epithelial Cells Induces Monocyte Infiltration in 3D Culture, Linzhang Li, Jie Chen, Gaofeng Xiong, Daret K. St. Clair, Wei Xu, and Ren Xu

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Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice, Yi Liu, Cuiping Zhang, Zhenyu Li, Chi Wang, Jianhang Jia, Tianyan Gao, Gerhard C. Hildebrandt, Daohong Zhou, Subbarao Bondada, Peng Ji, Daret K. St. Clair, Jinze Liu, Chang-Guo Zhan, Hartmut Geiger, Shuxia Wang, and Ying Liang

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Mechanisms of Therapeutic Resistance in Prostate Cancer, Mary Nakazawa, Channing Paller, and Natasha Kyprianou

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Oxidative Stress-Induced JNK/AP-1 Signaling is a Major Pathway Involved in Selective Apoptosis of Myelodysplastic Syndrome Cells by Withaferin-A, Karine Z. Oben, Sara S. Alhakeem, Mary Kathryn McKenna, Jason A. Brandon, Rajeswaran Mani, Sunil K. Noothi, Jinpeng Liu, Shailaja Akunuru, Sanjit Kumar Dhar, Inder P. Singh, Ying Liang, Chi Wang, Ahmed Abdel-Latif, Harold F. Stills Jr., Daret K. St Clair, Hartmut Geiger, Natarajan Muthusamy, Kaoru Tohyama, Ramesh C. Gupta, and Subbarao Bondada

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Radiation Induced Apoptosis of Murine Bone Marrow Cells is Independent of Early Growth Response 1 (EGR1), Karine Z. Oben, Beth W. Gachuki, Sara S. Alhakeem, Mary Kathryn McKenna, Ying Liang, Daret K. St. Clair, Vivek M. Rangnekar, and Subbarao Bondada