This collection was named as Graduate Center for Toxicology Faculty Publications before Jan. 1, 2015.

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Submissions from 2017

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Lkb1 Inactivation Drives Lung Cancer Lineage Switching Governed by Polycomb Repressive Complex 2, Haikuo Zhang, Christine Fillmore Brainson, Shohei Koyama, Amanda J. Redig, Ting Chen, Shuai Li, Manav Gupta, Carolina Garcia-de-Alba, Margherita Paschini, Grit S. Herter-Sprie, Gang Lu, Xin Zhang, Bryan P. Marsh, Stephanie J. Tuminello, Chunxiao Xu, Zhao Chen, Xiaoen Wang, Esra A. Akbay, Mei Zheng, Sangeetha Palakurthi, Lynette M. Sholl, Anil K. Rustgi, David J. Kwiatkowski, J. Alan Diehl, Adam J. Bass, Norman E. Sharpless, Glenn Dranoff, Peter S. Hammerman, Hongbin Ji, Nabeel Bardeesy, Dieter Saur, Hideo Watanabe, Carla F. Kim, and Kwok-Kin Wong

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Glycolytic Reprogramming Through PCK2 Regulates Tumor Initiation of Prostate Cancer Cells, Jiangsha Zhao, Jieran Li, Teresa W.M. Fan, and Steven X. Hou

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A Novel Redox Regulator, MnTnBuOE-2-PyP5+, Enhances Normal Hematopoietic Stem/Progenitor Cell Function, Yanming Zhao, Dustin W. Carroll, Y. You, Luksana Chaiswing, R. Wen, I. Batinic-Haberle, Subbarao Bondada, Ying Liang, and Daret K. St Clair

Submissions from 2016

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Mechanism of Three-Component Collision to Produce Ultrastable pRNA Three-Way Junction of Phi29 DNA-Packaging Motor by Kinetic Assessment, Daniel W. Binzel, Emil F. Khisamutdinov, Mario Vieweger, Janice Ortega, Jingyuan Li, and Peixuan Guo

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A Cluster of Trace-Concentration Methamphetamine Identifications in Racehorses Associated with a Methamphetamine-Contaminated Horse Trailer: A Report and Analysis, Kimberly Brewer, Theodore F. Shults, Jacob Machin, Sucheta Kudrimoti, Rodney L. Eisenberg, Petra Hartman, Caroline Wang, Clara Fenger, Pierre Beaumier, and Thomas Tobin

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Simultaneous Quantitation of Oxidized and Reduced Glutathione via LC-MS/MS: An Insight into the Redox State of Hematopoietic Stem Cells, Dustin W. Carroll, Diana Howard, Haining Zhu, Christian M. Paumi, Mary Vore, Subbarao Bondada, Ying Liang, Chi Wang, and Daret K. St. Clair

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Dasatinib-loaded Albumin Nanoparticles Possess Diminished Endothelial Cell Barrier Disruption and Retain Potent Anti-Leukemia Cell Activity, Chunling Dong, Bo Li, Zhenyu Li, Sreerama Shetty, and Jian Fu

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Stable Isotope Resolved Metabolomics Studies in ex vivo Tissue Slices, Teresa W-M Fan, Andrew N. Lane, and Richard M. Higashi

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Methamphetamine: A Substance of Emerging Environmental Concern for Horse Racing, Clara Fenger, Tanya Boulmetis, Kim Brewer, Kent Stirling, and Thomas Tobin

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The Lowdown of Out-of-Competition Testing: What the RMTC Isn't Telling Us About Its Proposed Regulations, Clara Fenger, Tanya Boulmetis, Kim Brewer, and Thomas Tobin

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Enhanced Bovine Colostrum Supplementation Shortens the Duration of Respiratory Disease in Thoroughbred Yearlings, Clara K. Fenger, Thomas Tobin, Patrick J. Casey, Edward A. Roualdes, John L. Langemeier, Ruel Cowles, and Deborah M. Haines

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Exposure of Human Lung Cells to Tobacco Smoke Condensate Inhibits the Nucleotide Excision Repair Pathway, Nathaniel C. Holcomb, Mamta Goswami, Sung Gu Han, Samuel Clark, David K. Orren, C. Gary Gairola, and Isabel Mellon

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Melanocortin 1 Receptor: Structure, Function, and Regulation, Erin M. Wolf Horrell, Mary C. Boulanger, and John A. D'Orazio

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Changes in Mitochondrial Homeostasis and Redox Status in Astronauts Following Long Stays in Space, Hiroko P. Indo, Hideyuki J. Majima, Masahiro Terada, Shigeaki Suenaga, Kazuo Tomita, Shin Yamada, Akira Higashibata, Noriaki Ishioka, Takuro Kanekura, Ikuya Nonaka, Clare L. Hawkins, Michael J. Davies, Daret K. St Clair, and Chiaki Mukai

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The Nobel Prize in Chemistry 2015: Exciting Discoveries in DNA Repair by Aziz Sancar, David K. Orren

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Hexavalent Chromium Induces Malignant Transformation of Human Lung Bronchial Epithelial Cells Via ROS-Dependent Activation of miR-21-PDCD4 Signaling, Poyil Pratheeshkumar, Young-Ok Son, Sasidharan Padmaja Divya, Lilia Turcios, Ram Vinod Roy, John Andrew Hitron, Lei Wang, Donghern Kim, Jin Dai, Padmaja Asha, Zhuo Zhang, and Xianglin Shi

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S100A4 Drives Non-Small Cell Lung Cancer Invasion, Associates with Poor Prognosis, and is Effectively Targeted by the FDA-Approved Anti-Helminthic Agent Niclosamide, Rachel L. Stewart, Brittany L. Carpenter, Dava S. West, Teresa Knifley, Lili Liu, Chi Wang, Heidi L. Weiss, Tamas S. Gal, Eric B. Durbin, Susanne M. Arnold, Kathleen L. O'Connor, and Min Chen

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Elevated Integrin α6β4 Expression is Associated with Venous Invasion and Decreased Overall Survival in Non-Small Cell Lung Cancer, Rachel L. Stewart, Dava West, Chi Wang, Heidi L. Weiss, Tamas S. Gal, Eric B. Durbin, William O'Connor, Min Chen, and Kathleen L. O'Connor

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Metabolomics Workbench: An International Repository for Metabolomics Data and Metadata, Metabolite Standards, Protocols, Tutorials and Training, and Analysis Tools, Manish Sud, Eoin Fahy, Dawn Cotter, Kenan Azam, Ilango Vadivelu, Charles Burant, Arthur Edison, Oliver Fiehn, Richard M. Higashi, K. Sreekumaran Nair, Susan Sumner, and Shankar Subramaniam

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Analysis of RNA Expression of Normal and Cancer Tissues Reveals High Correlation of COP9 Gene Expression with Respiratory Chain Complex Components, Christina A. Wicker and Tadahide Izumi

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ErbB2 and p38γ MAPK Mediate Alcohol-Induced Increase in Breast Cancer Stem Cells and Metastasis, Mei Xu, Zhenhua Ren, Xin Wang, Ashley Comer, Jacqueline A. Frank, Zun-Ji Ke, Yi Huang, Zhuo Zhang, Xianglin Shi, Siying Wang, and Jia Luo

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Physicochemical Properties of Engineered Nanomaterials that Influence Their Nervous System Distribution and Effects, Robert A. Yokel

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HDAC6 Inhibition Prevents TNF-α-Induced Caspase 3 Activation in Lung Endothelial Cell and Maintains Cell-Cell Junctions, Jinyan Yu, Mengshi Ma, Zhongsen Ma, and Jian Fu

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Ubiquitin-Specific Peptidase 10 (USP10) Deubiquitinates and Stabilizes MutS Homolog 2 (MSH2) to Regulate Cellular Sensitivity to DNA Damage, Mu Zhang, Chen Hu, Dan Tong, Shengyan Xiang, Kendra Williams, Wenlong Bai, Guo-Min Li, Gerold Bepler, and Xiaohong Zhang

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H2AX Deficiency is Associated with Erythroid Dysplasia and Compromised Haematopoietic Stem Cell Function, Baobing Zhao, Timothy L. Tan, Yang Mei, Jing Yang, Yiting Yu, Amit Verma, Ying Liang, Juehua Gao, and Peng Ji