This collection was named as Graduate Center for Toxicology Faculty Publications before Jan. 1, 2015.

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Submissions from 2019

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The Benefits of Lasix for Exercise-Induced Pulmonary Hemorrhage: 50 Years of Science and Clinical Experience, Kimberly Brewer, Clara Fenger, and Thomas Tobin

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Protective Effects of Novel Derivatives of Vitamin D3 and Lumisterol Against UVB-Induced Damage in Human Keratinocytes Involve Activation of Nrf2 and p53 Defense Mechanisms, Anyamanee Chaiprasongsuk, Zorica Janjetovic, Tae-Kang Kim, Stuart G. Jarrett, John A. D'Orazio, Michael F. Holick, Edith K. Y. Tang, Robert C. Tuckey, Uraiwan Panich, Wei Li, and Andrzej T. Slominski

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MicroRNA Regulation of Epigenetic Modifiers in Breast Cancer, Brock Humphries, Zhishan Wang, and Chengfeng Yang

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Circular RNA circNOL10 Inhibits Lung Cancer Development by Promoting SCLM1-Mediated Transcriptional Regulation of the Humanin Polypeptide Family, Aruo Nan, Lijian Chen, Nan Zhang, Yangyang Jia, Xin Li, Hanyu Zhou, Yihui Ling, Zhishan Wang, Chengfeng Yang, Sijin Liu, and Yiguo Jiang

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A Case-Control Study of Trace-Element Status and Lung Cancer in Appalachian Kentucky, Jason M. Unrine, Stacey A. Slone, Wayne T. Sanderson, Nancy E. Johnson, Eric B. Durbin, Shristi Shrestha, Ellen J. Hahn, Fran Feltner, Bin Huang, W. Jay Christian, Isabel Mellon, David K. Orren, and Susanne M. Arnold

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Extracellular Vesicle-Mediated Macrophage Activation: An Insight Into the Mechanism of Thioredoxin-Mediated Immune Activation, Chontida Yarana, Hannah Thompson, Luksana Chaiswing, D. Allan Butterfield, Heidi L. Weiss, Subbarao Bondada, Sara S. Alhakeem, Suriyan Sukati, and Daret K. St. Clair

Submissions from 2018

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GRP78 Is a Targetable Receptor on Cancer and Stromal Cells, Nathalia Araujo, Nikhil Hebbar, and Vivek M. Rangnekar

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Acute Loss of Iron-Sulfur Clusters Results in Metabolic Reprogramming and Generation of Lipid Droplets in Mammalian Cells, Daniel R. Crooks, Nunziata Maio, Andrew N. Lane, Michal Jarnik, Richard M. Higashi, Ronald G. Haller, Ye Yang, Teresa Whei-Mei Fan, W. Marston Linehan, and Tracey A. Rouault

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Stable Isotope-Resolved Metabolomics Shows Metabolic Resistance to Anti-Cancer Selenite in 3D Spheroids Versus 2D Cell Cultures, Teresa W. -M. Fan, Salim S. El-Amouri, Jessica K. A. Macedo, Qing Jun Wang, Huan Song, Teresa Cassel, and Andrew N. Lane

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Lasix Lessons Learned: Science Confirms What American Horsemen Knew 50 Years Ago, Clara Fenger, Steve Selway, and Thomas Tobin

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Trace-Level Identifications Are Not Positives: The Scientifically Correct and Public Relations-Appropriate Approach to Medication Regulation, Clara Fenger and Thomas Tobin

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Hitting the Threshold of Common Sense: The Time for Screening Limits to Guard Against Environmental Transfer Is Now, Clara Fenger, Thomas Tobin, Maria Catignani, and Theodore Shults

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Beta-Catenin Cleavage Enhances Transcriptional Activation, Tatiana Goretsky, Emily M. Bradford, Qing Ye, Olivia F. Lamping, Tomas Vanagunas, Mary Pat Moyer, Patrick C. Keller, Preetika Sinh, Josep M. Llovet, Tianyan Gao, Qing-Bai She, Linheng Li, and Terrence A. Barrett

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Sirtuin 1-Mediated Deacetylation of XPA DNA Repair Protein Enhances Its Interaction with ATR Protein and Promotes cAMP-Induced DNA Repair of UV Damage, Stuart G. Jarrett, Katharine M. Carter, Robert-Marlo Bautista, Daheng He, Chi Wang, and John A. D’Orazio

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ALS Mutations of FUS Suppress Protein Translation and Disrupt the Regulation of Nonsense-Mediated Decay, Marisa Kamelgarn, Jing Chen, Lisha Kuang, Huan Jin, Edward J. Kasarskis, and Haining Zhu

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Doxorubicin-Induced Elevated Oxidative Stress and Neurochemical Alterations in Brain and Cognitive Decline: Protection by MESNA and Insights into Mechanisms of Chemotherapy-Induced Cognitive Impairment ("Chemobrain"), Jeriel T. R. Keeney, Xiaojia Ren, Govind Warrier, Teresa Noel, David K. Powell, Jennifer M. Brelsfoard, Rukhsana Sultana, Kathryn E. Saatman, Daret K. St. Clair, and D. Allan Butterfield

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Aged Murine Hematopoietic Stem Cells Drive Aging-Associate Immune Remodeling, Hanna Leins, Medhanie Mulaw, Karina Eiwen, Vadim Sakk, Ying Liang, Michael Denkinger, Hartmut Geiger, and Reinhold Schirmbeck

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Glutathione de Novo Synthesis but Not Recycling Process Coordinates with Glutamine Catabolism to Control Redox Homeostasis and Directs Murine T Cell Differentiation, Gaojian Lian, J. N. Rashida Gnanaprakasam, Tingting Wang, Ruohan Wu, Xuyong Chen, Lingling Liu, Yuqing Shen, Mao Yang, Jun Yang, Ying Chen, Vasilis Vasiliou, Teresa A. Cassel, Douglas R. Green, Yusen Liu, Teresa W. -M. Fan, and Ruoning Wang

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Nanoparticle-Mediated Therapeutic Agent Delivery for Treating Metastatic Breast Cancer—Challenges and Opportunities, Yunfei Li, Brock Humphries, Chengfeng Yang, and Zhishan Wang

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MTBP Inhibits the Erk1/2-Elk-1 Signaling in Hepatocellular Carcinoma, Atul Ranjan, Swathi V. Iyer, Christopher Ward, Tim Link, Francisco J. Diaz, Animesh Dhar, Ossama W. Tawfik, Steven A. Weinman, Yoshiaki Azuma, Tadahide Izumi, and Tomoo Iwakuma

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H3K9 Methyltransferases and Demethylases Control Lung Tumor-Propagating Cells and Lung Cancer Progression, S. P. Rowbotham, F Li, A. F. M. Dost, S. M. Louie, B. P. Marsh, P. Pessina, C. R. Anbarasu, Christine Fillmore Brainson, S. J. Tuminello, A. Lieberman, S. Ryeom, T. M. Schlaeger, B. J. Aronow, H. Watanabe, K. K. Wong, and C. F. Kim

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Rational Reasoning on Ractopamine: Kentucky Regulators Reach Appropriate Responses to Inconsequential Trace-Level Environmental Substance Identifications, Theodore F. Shults, Kimberly Brewer, Jake Machin, Eric Hamelback, and Thomas Tobin

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A Cross-Sectional Study of the Use and Effectiveness of the Individual Development Plan Among Doctoral Students, Nathan L. Vanderford, Teresa M. Evans, L. Todd Weiss, Lindsay Bira, and Jazmin Beltran-Gastelum

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Use and Effectiveness of the Individual Development Plan Among Postdoctoral Researchers: Findings from a Cross-Sectional Study, Nathan L. Vanderford, Teresa M. Evans, L. Todd Weiss, Lindsay Bira, and Jazmin Beltran-Gastelum

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Profiling Prostate Cancer Therapeutic Resistance, Cameron A. Wade and Natasha Kyprianou