This collection was named as Graduate Center for Toxicology Faculty Publications before Jan. 1, 2015.

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Submissions from 2021

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PI3K/mTOR Dual Inhibitor PF-04691502 Is a Schedule-Dependent Radiosensitizer for Gastroenteropancreatic Neuroendocrine Tumors, Zeta Chow, Jeremy Johnson, Aman Chauhan, Tadahide Izumi, Michael Cavnar, Heidi L. Weiss, Courtney M. Townsend Jr., Lowell B. Anthony, Carrigan Wasilchenko, Matthew L. Melton, Jörg Schrader, B. Mark Evers, and Piotr G. Rychahou

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Cancer Curriculum for Appalachian Kentucky Middle and High Schools, Lauren Hudson, Katherine Sharp, Chris Prichard, Melinda J. Ickes, Sahar Alameh, and Nathan L. Vanderford

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DNA Repair Pathways in Cancer Therapy and Resistance, Lan-ya Li, Yi-di Guan, Xi-sha Chen, Jin-ming Yang, and Yan Cheng

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NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics, Penghui Lin, Li Dai, Daniel R. Crooks, Leonard M. Neckers, Richard M. Higashi, Teresa W.-M. Fan, and Andrew N. Lane

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Apolipoprotein E Genotype-Dependent Nutrigenetic Effects to Prebiotic Inulin for Modulating Systemic Metabolism and Neuroprotection in Mice via Gut-Brain Axis, Lucille M. Yanckello, Jared D. Hoffman, Ya-Hsuan Chang, Penghui Lin, Geetika Nehra, George Chlipala, Scott D. McCulloch, Tyler C. Hammond, Andrew T. Yackzan, Andrew N. Lane, Stefan J. Green, Anika M. S. Hartz, and Ai-Ling Lin

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Lipid Metabolism as a Targetable Metabolic Vulnerability in Colorectal Cancer, Yekaterina Y. Zaytseva

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Co-Targeting Plk1 and DNMT3a in Advanced Prostate Cancer, Zhuangzhuang Zhang, Lijun Cheng, Qiongsi Zhang, Yifan Kong, Daheng He, Kunyu Li, Matthew Rea, Jianlin Wang, Ruixin Wang, Jinghui Liu, Zhiguo Li, Chongli Yuan, Enze Liu, Yvonne N. Fondufe-Mittendorf, Lang Li, Tao Han, Chi Wang, and Xiaoqi Liu

Submissions from 2020

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ITGA2 Promotes Expression of ACLY and CCND1 in Enhancing Breast Cancer Stemness and Metastasis, Valery Adorno-Cruz, Andrew D. Hoffmann, Xia Liu, Nurmaa K. Dashzeveg, Rokana Taftaf, Brian Wray, Ruth A. Keri, and Huiping Liu

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Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective, Teresa W-M Fan, Richard M. Higashi, Yelena Chernayavskaya, and Andrew N. Lane

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Spermine Synthase and MYC Cooperate to Maintain Colorectal Cancer Cell Survival by Repressing Bim Expression, Yubin Guo, Qing Ye, Pan Deng, Yanan Cao, Daheng He, Zhaohe Zhou, Chi Wang, Yekaterina Y. Zaytseva, Charles E. Schwartz, Eun Young Lee, B. Mark Evers, Andrew J. Morris, Side Liu, and Qing-Bai She

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A Brief Educational Intervention Enhances Basic Cancer Literacy among Kentucky Middle and High School Students, Lauren Hudson, Kerrigan M. Samons, Haley E. Dicken, Chris Prichard, L. Todd Weiss, Jean Edward, Robin C. Vanderpool, and Nathan L. Vanderford

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Rho GTPases: Big Players in Breast Cancer Initiation, Metastasis and Therapeutic Responses, Brock Humphries, Zhishan Wang, and Chengfeng Yang

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Communication of Professional Readiness in Dietetics and Human Nutrition Undergraduates: A Pilot Study, Heather Norman-Burgdolf, Emily M. DeWitt, Nathan L. Vanderford, and Julie Plasencia

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SOD2 Deficiency in Cardiomyocytes Defines Defective Mitochondrial Bioenergetics as a Cause of Lethal Dilated Cardiomyopathy, Sudha Sharma, Susmita Bhattarai, Hosne Ara, Grace Sun, Daret K. St. Clair, Md Shenuarin Bhuiyan, Christopher Kevil, Megan N. Watts, Paari Dominic, Takahiko Shimizu, Kevin J. McCarthy, Hong Sun, Manikandan Panchatcharam, and Sumitra Miriyala

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IGF-1R Inhibition Induces MEK Phosphorylation to Promote Survival in Colon Carcinomas, Qing Wang, Yan Zhang, Jiang Zhu, Honggang Zheng, Shuntai Chen, Li Chen, and Hsin-Sheng Yang

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Epigenetic Regulation of Prostate Cancer, Ruixin Wang and Xiaoqi Liu

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Develop a High-Throughput Screening Method to Identify C-P4H1 (Collagen Prolyl 4-Hydroxylase 1) Inhibitors from FDA-Approved Chemicals, Shike Wang, Kuo-Hao Lee, Nathália Victoria Araujo, Chang-Guo Zhan, Vivek M. Rangnekar, and Ren Xu

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HDAC6 Mediates Macrophage iNOS Expression and Excessive Nitric Oxide Production in the Blood During Endotoxemia, Yan Wang, Ke Wang, and Jian Fu

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Neutrophil: A New Player in Metastatic Cancers, Mengyue Wu, Mutian Ma, Zhenya Tan, Hong Zheng, and Xia Liu

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Upregulation of CPT1A Is Essential for the Tumor-Promoting Effect of Adipocytes in Colon Cancer, Xiaopeng Xiong, Yang-An Wen, Rachelle Fairchild, Yekaterina Y. Zaytseva, Heidi L. Weiss, B. Mark Evers, and Tianyan Gao

Submissions from 2019

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The Benefits of Lasix for Exercise-Induced Pulmonary Hemorrhage: 50 Years of Science and Clinical Experience, Kimberly Brewer, Clara Fenger, and Thomas Tobin

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Protective Effects of Novel Derivatives of Vitamin D3 and Lumisterol Against UVB-Induced Damage in Human Keratinocytes Involve Activation of Nrf2 and p53 Defense Mechanisms, Anyamanee Chaiprasongsuk, Zorica Janjetovic, Tae-Kang Kim, Stuart G. Jarrett, John A. D'Orazio, Michael F. Holick, Edith K. Y. Tang, Robert C. Tuckey, Uraiwan Panich, Wei Li, and Andrzej T. Slominski

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N-Glycosylation-Defective Splice Variants of Neuropilin-1 Promote Metastasis by Activating Endosomal Signals, Xiuping Huang, Qing Ye, Min Chen, Aimin Li, Wenting Mi, Yuxin Fang, Yekaterina Y. Zaytseva, Kathleen L. O'Connor, Craig W. Vander Kooi, Side Liu, and Qing-Bai She

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MicroRNA Regulation of Epigenetic Modifiers in Breast Cancer, Brock Humphries, Zhishan Wang, and Chengfeng Yang

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Aminorex Identified in Horse Urine Following Consumption of Barbarea vulgaris; a Preliminary Report, George Maylin, Clara Fenger, Jacob Machin, Sucheta Kudrimoti, Rodney Eisenberg, Jonathan D. Green, and Thomas Tobin