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Submissions from 2022

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Synthesis and Characterization of d5-Barbarin for Use in Barbarin-Related Research, Sucheta Kudrimoti, Jacob Machin, Adedamola S. Arojojoye, Samuel G. Awuah, Rodney Eisenberg, Clara Fenger, George Maylin, Andreas F. Lehner, and Thomas Tobin

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Sex Differences in Kappa Opioid Receptor Agonist Mediated Attenuation of Chemotherapy-Induced Neuropathic Pain in Mice, Kelly F. Paton, Dan Luo, Anne C. La Flamme, Thomas E. Prisinzano, and Bronwyn M. Kivell

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Similarly Efficacious Anti-Malarial Drugs SJ733 and Pyronaridine Differ in Their Ability to Remove Circulating Parasites in Mice, Arya SheelaNair, Aleksandra S. Romanczuk, Rosemary A. Aogo, Rohit Nemai Haldar, Lianne I. M. Lansink, Deborah Cromer, Yandira G. Salinas, R. Kiplin Guy, James S. McCarthy, Miles P. Davenport, Ashraful Haque, and David S. Khoury

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Cerium dioxide, a Jekyll and Hyde nanomaterial, can increase basal and decrease elevated inflammation and oxidative stress, Robert Yokel, Marsha L. Ensor, Hemendra J. Vekaria, Patrick G. Sullivan, David J. Feola, Arnold Stromberg, Michael T. Tseng, and Douglas A. Harrison

Submissions from 2021

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Rapid-Onset Anti-Stress Effects of a Kappa-Opioid Receptor Antagonist, LY2795050, against Immobility in an Open Space Swim Paradigm in Male and Female Mice, Caroline Baynard, Thomas E. Prisinzano, and Eduardo R. Butelman

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Siderophore-Mediated Zinc Acquisition Enhances Enterobacterial Colonization of the Inflamed Gut, Judith Behnsen, Hui Zhi, Allegra T. Aron, Venkateswaran Subramanian, William Santus, Michael H. Lee, Romana R. Gerner, Daniel Petras, Janet Z. Liu, Keith D. Green, Sarah L. Price, Jose Camacho, Hannah Hillman, Joshua Tjokrosurjo, Nicola P. Montaldo, Evelyn M. Hoover, Sean Treacy-Abarca, Benjamin A. Gilston, Eric P. Skaar, Walter J. Chazin, Sylvie Garneau-Tsodikova, Matthew B Lawrenz, Robert D Perry, Sean-Paul Nuccio, Pieter C. Dorrestein, and Manuela Raffatellu

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A Brief Review of FDA’s Novel Tools for Ensuring Pharmaceutical Quality in the Human Drug Supply Chain, Heather R. Campbell and Robert A. Lodder

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Innovative Computational Methods for Pharmaceutical Problem Solving a Review Part II: Serious Gaming, Heather R. Campbell and Robert A. Lodder

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Innovative Computational Methods for Pharmaceutical Problem Solving a Review Part I: The Drug Development Process, Heather R. Campbell and Robert A. Lodder

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Monetary Incentives for Producing Counterfeit, Adulterated, and Misbranded Medicine: Case Studies and Examples, Heather R. Campbell and Robert A. Lodder

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Selecting an Anti-Malarial Clinical Candidate from Two Potent Dihydroisoquinolones, Yizhe Chen, Fangyi Zhu, Jared T. Hammill, Gloria Holbrook, Lei Yang, Burgess Freeman, Karen L. White, David M. Shackleford, Kathleen G. O'Loughlin, Susan A. Charman, Jon C. Mirsalis, and R. Kiplin Guy

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Nalfurafine Reduces Neuroinflammation and Drives Remyelination in Models of CNS Demyelinating Disease, Lisa Denny, Afnan Al Abadey, Katharina Robichon, Nikki Templeton, Thomas E. Prisinzano, Bronwyn M. Kivell, and Anne C. La Flamme

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Protecting P-Glycoprotein at the Blood-Brain Barrier from Degradation in an Alzheimer's Disease Mouse Model, Yujie Ding, Yu Zhong, Andrea Baldeshwiler, Erin L. Abner, Björn Bauer, and Anika M. S. Hartz

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Comprehensive Analysis of NAC Transcription Factor Family Uncovers Drought and Salinity Stress Response in Pearl Millet (Pennisetum glaucum), Ambika Dudhate, Harshraj Shinde, Pei Yu, Daisuke Tsugama, Shashi Kumar Gupta, Shenkui Liu, and Tetsuo Takano

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Autoradiographic Localization of [3H]-Nisoxetine Binding Sites in the CNS of Male and Female Japanese Quail, Shannon E. Eaton, James R. Pauly, Deann M. Hopkins, and Chana K. Akins

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Metal-Free Domino Amination-Knoevenagel Condensation Approach to Access New Coumarins as Potent Nanomolar Inhibitors of VEGFR-2 and EGFR, Essam M. Eliwa, Marcel Frese, Ahmed H. Halawa, Maha M. Soltan, Larissa V. Ponomareva, Jon S. Thorson, Khaled A. Shaaban, Mohamed Shaaban, Ahmed M. El-Agrody, and Norbert Sewald

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The Characterization of Purified Citrate-Coated Cerium Oxide Nanoparticles Prepared via Hydrothermal Synthesis, Matthew L. Hancock, Robert A. Yokel, Matthew J. Beck, Julie L. Calahan, Travis W. Jarrells, Eric J. Munson, George A. Olaniyan, and Eric A. Grulke

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Design, Synthesis, and Preliminary Evaluation of a Potential Synthetic Opioid Rescue Agent, Sidnee L. Hedrick, Dan Luo, Sophia Kaska, Kumar Kulldeep Niloy, Karen Jackson, Rupam Sarma, Jamie Horn, Caroline Baynard, Markos Leggas, Eduardo R. Butelman, Mary Jeanne Kreek, and Thomas E. Prisinzano

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KEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung Cancer, Kristen S. Hill, Anthony McDowell Jr., J. Robert McCorkle, Erin Schuler, Sally R. Ellingson, Rina Plattner, and Jill M. Kolesar

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Endophytes of Brazilian Medicinal Plants with Activity against Phytopathogens, Jucélia Iantas, Daiani Cristina Savi, Renata da Silva Schibelbein, Sandriele Aparecida Noriler, Beatriz Marques Assad, Guilherme Dilarri, Henrique Ferreira, Jürgen Rohr, Jon S. Thorson, Khaled A. Shaaban, and Chirlei Glienke

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In Situ Imaging of Bacterial Outer Membrane Projections and Associated Protein Complexes Using Electron Cryo-Tomography, Mohammed Kaplan, Georges Chreifi, Lauren Ann Metskas, Janine Liedtke, Cecily R. Wood, Catherine M. Oikonomou, William J. Nicolas, Poorna Subramanian, Lori A. Zacharoff, Yuhang Wang, Yi-Wei Chang, Morgan Beeby, Megan J. Dobro, Yongtao Zhu, Mark J. McBride, Ariane Briegel, Carrie L. Shaffer, and Grant J. Jensen

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Functional Activation of Newborn Neurons Following Alcohol-Induced Reactive Neurogenesis, Natalie N. Nawarawong, Chelsea G. Nickell, Deann M. Hopkins, James R. Pauly, and Kimberly Nixon

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Total Synthesis of Decahydroquinoline Poison Frog Alkaloids ent-cis-195A and cis-211A, Takuya Okada, Naizhen Wu, Katsuki Takashima, Jungoh Ishimura, Hiroyuki Morita, Takuya Ito, Takeshi Kodama, Yuhei Yamasaki, Shin-Ichi Akanuma, Yoshiyuki Kubo, Ken-Ichi Hosoya, Hiroshi Tsuneki, Tsutomu Wada, Toshiyasu Sasaoka, Takahiro Shimizu, Hideki Sakai, Linda P. Dwoskin, Syed R. Hussaini, Ralph A. Saporito, and Naoki Toyooka

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Neuron-Derived Extracellular Vesicles Modulate Microglia Activation and Function, Hui Peng, Brock T. Harvey, Christopher I. Richards, and Kimberly Nixon

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Laser Irradiation as a Novel Alternative to Detach Intact Particulate Matter Collected on Air Filters, Seyed-Mohammadreza Samaee, Rahim Molaei, Robert A. Yokel, and Hedieh Pazokian