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Submissions from 2021

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Design, Synthesis, and Preliminary Evaluation of a Potential Synthetic Opioid Rescue Agent, Sidnee L. Hedrick, Dan Luo, Sophia Kaska, Kumar Kulldeep Niloy, Karen Jackson, Rupam Sarma, Jamie Horn, Caroline Baynard, Markos Leggas, Eduardo R. Butelman, Mary Jeanne Kreek, and Thomas E. Prisinzano

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KEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung Cancer, Kristen S. Hill, Anthony McDowell Jr., J. Robert McCorkle, Erin Schuler, Sally R. Ellingson, Rina Plattner, and Jill M. Kolesar

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Endophytes of Brazilian Medicinal Plants with Activity against Phytopathogens, Jucélia Iantas, Daiani Cristina Savi, Renata da Silva Schibelbein, Sandriele Aparecida Noriler, Beatriz Marques Assad, Guilherme Dilarri, Henrique Ferreira, Jürgen Rohr, Jon S. Thorson, Khaled A. Shaaban, and Chirlei Glienke

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In Situ Imaging of Bacterial Outer Membrane Projections and Associated Protein Complexes Using Electron Cryo-Tomography, Mohammed Kaplan, Georges Chreifi, Lauren Ann Metskas, Janine Liedtke, Cecily R. Wood, Catherine M. Oikonomou, William J. Nicolas, Poorna Subramanian, Lori A. Zacharoff, Yuhang Wang, Yi-Wei Chang, Morgan Beeby, Megan J. Dobro, Yongtao Zhu, Mark J. McBride, Ariane Briegel, Carrie L. Shaffer, and Grant J. Jensen

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Functional Activation of Newborn Neurons Following Alcohol-Induced Reactive Neurogenesis, Natalie N. Nawarawong, Chelsea G. Nickell, Deann M. Hopkins, James R. Pauly, and Kimberly Nixon

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Total Synthesis of Decahydroquinoline Poison Frog Alkaloids ent-cis-195A and cis-211A, Takuya Okada, Naizhen Wu, Katsuki Takashima, Jungoh Ishimura, Hiroyuki Morita, Takuya Ito, Takeshi Kodama, Yuhei Yamasaki, Shin-Ichi Akanuma, Yoshiyuki Kubo, Ken-Ichi Hosoya, Hiroshi Tsuneki, Tsutomu Wada, Toshiyasu Sasaoka, Takahiro Shimizu, Hideki Sakai, Linda P. Dwoskin, Syed R. Hussaini, Ralph A. Saporito, and Naoki Toyooka

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Neuron-Derived Extracellular Vesicles Modulate Microglia Activation and Function, Hui Peng, Brock T. Harvey, Christopher I. Richards, and Kimberly Nixon

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Laser Irradiation as a Novel Alternative to Detach Intact Particulate Matter Collected on Air Filters, Seyed-Mohammadreza Samaee, Rahim Molaei, Robert A. Yokel, and Hedieh Pazokian

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Mithramycin and Analogs for Overcoming Cisplatin Resistance in Ovarian Cancer, David Schweer, J. Robert McCorkle, Jurgen Rohr, Oleg V. Tsodikov, Frederick R. Ueland, and Jill M. Kolesar

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Mansouramycins E–G, Cytotoxic Isoquinolinequinones from Marine Streptomycetes, Mohamed Shaaban, Khaled A. Shaaban, Gerhard Kelter, Heinz Herbert Fiebig, and Hartmut Laatsch

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Age and Sex Are Associated with the Plasma Lipidome: Findings from the GOLDN Study, Emily Slade, Marguerite R. Irvin, Kevin Xie, Donna K. Arnett, Steven A. Claas, Tobias Kind, David W. Fardo, and Gregory A. Graf

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Clinical Pharmacology and Dosing Regimen Optimization of Neonatal Opioid Withdrawal Syndrome Treatments, Fei Tang, Chee M. Ng, Henrietta S. Bada, and Markos Leggas

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Landomycins as Glutathione-Depleting Agents and Natural Fluorescent Probes for Cellular Michael Adduct-Dependent Quinone Metabolism, Alessio Terenzi, Mery La Franca, Sushilla van Schoonhoven, Rostyslav Panchuk, Álvaro Martínez, Petra Heffeter, Redding Gober, Christine Pirker, Petra Vician, Christian R. Kowol, Rostyslav Stoika, Luca Salassa, Jürgen Rohr, and Walter Berger

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Genomic Data from NSCLC Tumors Reveals Correlation between SHP-2 Activity and PD-L1 Expression and Suggests Synergy in Combining SHP-2 and PD-1/PD-L1 Inhibitors, Keller J. Toral, Mark A. Wuenschel, and Esther P. Black

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Immunostimulatory Membrane Proteins Potentiate H. pylori-Induced Carcinogenesis by Enabling CagA Translocation, Matthew G. Varga, Cecily R. Wood, Julia Butt, Mackenzie E. Ryan, Wei-Cheng You, Kaifeng Pan, Tim Waterboer, Meira Epplein, and Carrie L. Shaffer

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Immunomodulatory Effects of Azithromycin Revisited: Potential Applications to COVID-19, Vincent J. Venditto, Dalia Haydar, Ahmed K. Abdel-Latif, John C. Gensel, Michael I. Anstead, Michelle G. Pitts, Jarrod W. Creameans, Timothy J. Kopper, Chi Peng, and David J. Feola

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Sitosterolemia: Twenty Years of Discovery of the Function of ABCG5ABCG8, Kori Williams, Allison Segard, and Gregory A. Graf

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Correction to Some Statements about Aluminum in Sulaiman et al., Robert A. Yokel

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Direct Nose to the Brain Nanomedicine Delivery Presents a Formidable Challenge, Robert A. Yokel

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The Preparation Temperature Influences the Physicochemical Nature and Activity of Nanoceria, Robert A. Yokel, Wendel Wohlleben, Johannes Georg Keller, Matthew L. Hancock, Jason M. Unrine, D. Allan Butterfield, and Eric A. Grulke

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Clinical Data Mining Reveals Analgesic Effects of Lapatinib in Cancer Patients, Shuo Zhou, Fang Zheng, and Chang-Guo Zhan

Submissions from 2020

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Liposomal Delivery of Azithromycin Enhances Its Immunotherapeutic Efficacy and Reduces Toxicity in Myocardial Infarction, Ahmed Al-Darraji, Renée R. Donahue, Himi Tripathi, Hsuan Peng, Bryana M. Levitan, Lakshman Chelvarajan, Dalia Haydar, Erhe Gao, David Henson, John C. Gensel, David J. Feola, Vincent J. Venditto, and Ahmed K. Abdel-Latif

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Synthesis, Characterization, and Antiproliferative Activity of Novel Chiral [QuinoxP*AuCl2]+ Complexes, Adedamola S. Arojojoye, R. Tyler Mertens, Samuel Ofori, Sean R. Parkin, and Samuel G. Awuah

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David S. Miller: Scientist, Mentor, Friend--A Tribute and Thank You, Björn Bauer, J. Larry Renfro, Karl J. Karnaky, Rosalinde Masereeuw, Gert Fricker, Ron E. Cannon, and Anika M. S. Hartz

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Plasma and Serum Proteins Bound to Nanoceria: Insights into Pathways by which Nanoceria May Exert Its Beneficial and Deleterious Effects In Vivo, D. Allan Butterfield, Binghui Wang, Peng Wu, Sarita S. Hardas, Jason M. Unrine, Eric A. Grulke, Jian Cai, Jon B. Klein, William M. Pierce, Robert A. Yokel, and Rukhsana Sultana