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Submissions from 2018

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Physiologically Based Pharmacokinetic Modeling of Nanoceria Systemic Distribution in Rats Suggests Dose- and Route-Dependent Biokinetics, Ulrika Carlander, Tshepo Paulsen Moto, Anteneh Assefa Desalegn, Robert A. Yokel, and Gunnar Johanson

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Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order, Zheng Cui, Xia-Chang Wang, Xiaodong Liu, Anke Lemke, Stefan Koppermann, Christian Ducho, Jürgen Rohr, Jon S. Thorson, and Steven G. Van Lanen

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Structure-Based Discovery of mPGES-1 Inhibitors Suitable for Preclinical Testing in Wild-Type Mice as a New Generation of Anti-Inflammatory Drugs, Kai Ding, Ziyuan Zhou, Shurong Hou, Yaxia Yuan, Shuo Zhou, Xirong Zheng, Jianzhong Chen, Charles D. Loftin, Fang Zheng, and Chang-Guo Zhan

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Differential Effects of Linkers on the Activity of Amphiphilic Tobramycin Antifungals, Marina Y. Fosso, Sanjib K. Shrestha, Nishad Thamban Chandrika, Emily K. Dennis, Keith D. Green, and Sylvie Garneau-Tsodikova

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Isolation of Cerebral Capillaries from Fresh Human Brain Tissue, Anika M. S. Hartz, Julia A. Schulz, Brent S. Sokola, Stephanie E. Edelmann, Andrew N. Shen, Ralf G. Rempe, Yu Zhong, Nader El Seblani, and Bjoern Bauer

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Preventing P-gp Ubiquitination Lowers Aβ Brain Levels in an Alzheimer's Disease Mouse Model, Anika M. S. Hartz, Yu Zhong, Andrew N. Shen, Erin L. Abner, and Björn Bauer

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Agronomic and Chemical Performance of Field-Grown Tobacco Engineered for Triterpene and Methylated Triterpene Metabolism, Zuodong Jiang, Chase Kempinski, Santosh Kumar, Scott Kinison, Kristin Linscott, Eric Nybo, Sarah Janze, Constance Wood, and Joseph Chappell

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Ketogenic Diet Enhances Neurovascular Function with Altered Gut Microbiome in Young Healthy Mice, David Ma, Amy C. Wang, Ishita Parikh, Stefan J. Green, Jared D. Hoffman, George Chlipala, M. Paul Murphy, Brent S. Sokola, Björn Bauer, Anika M. S. Hartz, and Ai-Ling Lin

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Amine Containing Analogs of Sulindac for Cancer Prevention, Bini Mathew, Judith V. Hobrath, Michele C. Connelly, R. Kiplin Guy, and Robert C. Reynolds

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ABCG5 and ABCG8: More Than a Defense Against Xenosterols, Shailendra B. Patel, Gregory A. Graf, and Ryan E. Temel

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Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy, Ralf G. Rempe, Anika M. S. Hartz, Emma L. B. Soldner, Brent S. Sokola, Satya R. Alluri, Erin L. Abner, Richard J. Kryscio, Anton Pekcec, Juli Schlichtiger, and Björn Bauer

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Phaeophleospora vochysiae Savi & Glienke sp. nov. Isolated from Vochysia divergens Found in the Pantanal, Brazil, Produces Bioactive Secondary Metabolites, Daiani C. Savi, Khaled A. Shaaban, Francielly M. W. Gos, Larissa V. Ponomareva, Jon S. Thorson, Chirlei Glienke, and Jürgen Rohr

Submissions from 2017

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Phase 1b Trial of Proteasome Inhibitor Carfilzomib with Irinotecan in Lung Cancer and Other Irinotecan-Sensitive Malignancies That Have Progressed on Prior Therapy (Onyx IST Reference Number: CAR-IST-553), Susanne M. Arnold, Kari Chansky, Markos Leggas, Michael A. Thompson, John L. Villano, John Hamm, Rachel E. Sanborn, Glen J. Weiss, Gurkamal Chatta, and Maria Q. Baggstrom

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Draft Nuclear Genome Sequence of the Liquid Hydrocarbon–Accumulating Green Microalga Botryococcus braunii Race B (Showa), Daniel R. Browne, Jerry Jenkins, Jeremy Schmutz, Shengqiang Shu, Kerrie Barry, Jane Grimwood, Jennifer Chiniquy, Aditi Sharma, Thomas Daniel Niehaus, Taylor L. Weiss, Andrew T. Koppisch, David T. Fox, Suraj Dhungana, Shigeru Okada, Joe Chappell, and Timothy P. Devarenne

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A New Approach to Synthesize of 4-Phenacylideneflavene Derivatives and to Evaluate Their Cytotoxic Effects on HepG2 Cell Line, Hongbin Chen, Yang Xu, Yinan Zhang, and Zongping Zheng

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Immune Checkpoint Inhibition and the Prevalence of Autoimmune Disorders Among Patients with Lung and Renal Cancer, Sherif M. El-Refai

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Data for High-Throughput Estimation of Specific Activities of Enzyme/Mutants in Cell Lysates Through Immunoturbidimetric Assay of Proteins, Yiran Feng, Xiaolan Yang, Huimin Chong, Deqiang Wang, Xiaolei Hu, Chang-Guo Zhan, and Fei Liao

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Antibacterial Activity of Endophytic Actinomycetes Isolated from the Medicinal Plant Vochysia divergens (Pantanal, Brazil), Francielly M. W. Gos, Daiani C. Savi, Khaled A. Shaaban, Jon S. Thorson, Rodrigo Aluizio, Yvelise M. Possiede, Jürgen Rohr, and Chirlei Glienke

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Age Drives Distortion of Brain Metabolic, Vascular and Cognitive Functions, and the Gut Microbiome, Jared D. Hoffman, Ishita Parikh, Stefan J. Green, George Chlipala, Robert P. Mohney, Mignon Keaton, Bjoern Bauer, Anika M. S. Hartz, and Ai-Ling Lin

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Discovery of a Diaminopyrimidine FLT3 Inhibitor Active Against Acute Myeloid Leukemia, Jamie A. Jarusiewicz, Jae Yoon Jeon, Michele C. Connelly, Yizhe Chen, Lei Yang, Sharyn D. Baker, and R. Kiplin Guy

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Regioselective Baeyer–Villiger Oxidation of Lignin Model Compounds with Tin Beta Zeolite Catalyst and Hydrogen Peroxide, John Adam Jennings, Sean R. Parkin, Eric Munson, Sean Delaney, Julie L. Calahan, Mark Isaacs, Kunlun Hong, and Mark Crocker

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Computer-Aided Drug Design of Capuramycin Analogues as Anti-Tuberculosis Antibiotics by 3D-QSAR and Molecular Docking, Yuanyuan Jin, Shuai Fan, Guangxin Lv, Haoyi Meng, Zhengyang Sun, Wei Jiang, Steven G. Van Lanen, and Zhaoyong Yang

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Structural Basis for EarP-Mediated Arginine Glycosylation of Translation Elongation Factor EF-P, Ralph Krafczyk, Jakub Macošek, Pravin Kumar Ankush Jagtap, Daniel Gast, Swetlana Wunder, Prithiba Mitra, Amit Kumar Jha, Jürgen Rohr, Anja Hoffmann-Röder, Kirsten Jung, Janosch Hennig, and Jürgen Lassak

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A MicroRNA Signature of Response to Erlotinib is Descriptive of TGFβ Behaviour in NSCLC, Madeline J. Krentz Gober, James P. Collard, Katherine L. Thompson, and Esther P. Black

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Plant-Expressed Cocaine Hydrolase Variants of Butyrylcholinesterase Exhibit Altered Allosteric Effects of Cholinesterase Activity and Increased Inhibitor Sensitivity, Katherine E. Larrimore, I. Can Kazan, Latha Kannan, R. Player Kendle, Tameem Jamal, Matthew Barcus, Ashini Bolia, Stephen Brimijoin, Chang-Guo Zhan, S. Banu Ozkan, and Tsafrir S. Mor