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Dissertations from 2010

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THE ROLE OF ABCG2 IN DRUG ACTIVE TRANSPORT IN MILK, Lipeng Wang

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MODULATION OF THE ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR FOLLOWING EXPERIMENTAL RAT BRAIN INJURY IMPROVES CELLULAR AND BEHAVIORAL OUTCOMES, Thomas Matt Woodcock

Dissertations from 2009

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COMPUTATIONAL DESIGN OF 3-PHOSPHOINOSITIDE DEPENDENT KINASE-1 INHIBITORS AS POTENTIAL ANTI-CANCER AGENTS, Mohamed Diwan Mohideen AbdulHameed

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THE PHARMACOGENOMICS OF EGFR-DEPENDENT NSCLC: PREDICTING AND ENHANCING RESPONSE TO TARGETED EGFR THERAPY, Justin M. Balko

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SYNTHESIS AND EVALUATION OF PROUTEOLYSIS TAURGETING CHIMERAS (PROTACs): A POTENTIAL CHEMICAL GENETIC APPROACH TO BREAST CANCER THERAPY, Kedra C. Cyrus

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PREPARATION AND CHARACTERIZATION OF BLACKBERRY EXTRACTS AND THEIR ANTICANCER AND ANTI-INFLAMMATORY PROPERTIES, Jin Dai

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LIPID-BASED PACLITAXEL AND DOXORUBICIN NANOPARTICLES TO OVERCOME P-GP-MEDIATED DRUG RESISTANCE IN SOLID TUMORS, Xiaowei Dong

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STUDIES ON DRUG SOLUBILIZATION MECHANISM IN SIMPLE MICELLE SYSTEMS, Shaoxin Feng

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INSIGHTS INTO EXPRESSION, CELLULAR LOCALIZATION, AND REGULATION OF SUPERNATANT PROTEIN FACTOR, A PUTATIVE REGULATOR OF CHOLESTEROL BIOSYNTHESIS, Elzbieta Ilona Stolarczyk

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EXPERIMENTAL AND MOLECULAR DYNAMICS SIMULATION STUDIES OF PARTITIONING AND TRANSPORT ACROSS LIPID BILAYER MEMBRANES, Ravindra Wadhumal Tejwani

Dissertations from 2008

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SELECTIVE REGULATION OF CARDIOMYOCYTE SIGNALING BY RGL2, Leah M. Allen

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APPLICATION OF LINEAR FREE ENERGY RELATIONSHIPS IN THE PREDICTION OF TRIGLYCERIDE/WATER PARTITION COEFFICIENTS AND LIPID BILAYER PERMEABILITY COEFFICIENTS OF SMALL ORGANIC MOLECULES AND PEPTIDES, Yichen Cao

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TARGETING THE METAL CHELATOR D-PENICILLAMINE TO EXPLOIT THE ELEVATED COPPER AND OXIDATIVE STRESS ASSOCIATED WITH CANCER, Anshul Gupte

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DESIGN, SYNTHESIS, AND PHARMACOLOGICAL EVALUATION OF A SERIES OF NOVEL, GUANIDINE AND AMIDINE-CONTAINING NEONICOTINOID-LIKE ANALOGS OF NICOTINE: SUBTYPE-SELECTIVE INTERACTIONS AT NEURONAL NICOTINIC-ACETYLCHOLINE RECEPTOR., Aaron Joseph Haubner

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A NOVEL CLASS OF IMMUNOPROTEASOME CATALYTIC SUBUNIT LMP2 INHIBITOR AND ITS THERAPEUTIC POTENTIALS IN CANCER, Yik Khuan (Abby) Ho

Dissertations from 2007

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DRUG MILK TO SERUM RATIO PREDICTION AND ONTOGENY OF CYP3A CLEARANCE PATHWAY AS A MODEL OF DRUG EXPOSURE IN THE DEVELOPING RAT, Maggie Magdi Abbassi

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NEONATAL IMMUNE MODULATION TO IMPROVE PNEUMOCYSTIS CLEARANCE, Kerry McGarr Empey

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XENOBIOTIC TRANSPORTERS IN LACTATING MAMMARY EPITHELIAL CELLS: PREDICTIONS FOR DRUG ACCUMULATION IN BREAST MILK, Philip Earle Empey

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CYCLOOXYGENASE-2-DEPENDENT REMODELING OF THE DUCTUS ARTERIOSUS, Darshini Trivedi

Dissertations from 2006

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SYNTHESIS AND EVALUATION OF PYRIDINIUM DERIVATIVES AS CENTRAL NERVOUS SYSTEM NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS, Joshua Thomas Longen Ayers

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HEPATIC CYTOCHROME P450 REDUCTASE-NULL MICE AS AN ANIMAL MODEL TO STUDY ELECTRON TRANSFER PATHWAYS IN CHOLESTEROL SYNTHESIS AND CYP2E1-MEDIATED DRUG METABOLISM, Li Li

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CHEMOMETRICS, SPECTROMETRY, AND SENSORS FOR INTEGRATED SENSING AND PROCESSING: ADVANCING PROCESS ANALYTICAL TECHNOLOGY, Joseph Peter Medendorp

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NICOTINIC RECEPTOR MODULATION OF DOPAMINE TRANSPORTERS, Lisa Sue Middleton

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PHARMACEUTICALLY ENGINEERED NANOPARTICLES FOR ENHANCING IMMUNE RESPONSES TO HIV-1 TAT AND GAG p24 PROTEINS, Jigna D. Patel

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SYNTHETIC AROMATIC AGMATINE ANALOGS AS ALLOSTERIC MODULATORS OF THE N-METHYL-D-ASPARTATE (NMDA) RECEPTOR CHANNEL, Joshua Roderick Ring