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Submissions from 2015

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Genome-Wide Profiling of PARP1 Reveals an Interplay with Gene Regulatory Regions and DNA Methylation, Narasimharao Nalabothula, Taha Al-Jumaily, Abdallah M. Eteleeb, Robert M. Flight, Shao Xiaorong, Hunter Moseley, Eric C. Rouchka, and Yvonne N. Fondufe-Mittendorf

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Autophagy Is Induced Upon Platelet Activation and Is Essential for Hemostasis and Thrombosis, Madhu M. Ouseph, Yunjie Huang, Meenakshi Banerjee, Smita Joshi, Laura MacDonald, Yu Zhong, Huijuan Liu, Xianting Li, Binggang Xiang, Guoying Zhang, Masaaki Komatsu, Zhenyu Yue, Zhenyu Li, Brian Storrie, Sidney W. Whiteheart, and Qing Jun Wang

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Structural Mechanism of Laforin Function in Glycogen Dephosphorylation and Lafora Disease, Madushi Raththagala, M. Kathryn Brewer, Matthew W. Parker, Amanda R. Sherwood, Brian K. Wong, Simon Hsu, Travis M. Bridges, Bradley C. Paasch, Lance M. Hellman, Satrio Husodo, David A. Meekins, Adam O. Taylor, Benjamin D. Turner, Kyle D. Auger, Vikas V. Dukhande, Srinivas Chakravarthy, Pascual Sanz, Virgil L. Woods Jr., Sheng Li, Craig Vander Kooi, and Matthew S. Gentry

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Inorganic Arsenic-Induced Cellular Transformation is Coupled with Genome Wide Changes in Chromatin Structure, Transcriptome and Splicing Patterns, Caitlyn Riedmann, Ye Ma, Manana Melikishvili, Steven Grason Godfrey, Zhuo Zhang, Kuey-Chu Chen, Eric C. Rouchka, and Yvonne N. Fondufe-Mittendorf

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Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling, Jiandang Shi, Yajuan Liu, Xuehe Xu, Wen Zhang, Tianxin Yu, Jianhang Jia, and Chunming Liu

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Pharmacodynamic Assays to Facilitate Preclinical and Clinical Development of Pre-mRNA Splicing Modulatory Drug Candidates, Yihui Shi, Amanda S. Joyner, William Shadrick, Gustavo Palacios, Chandraiah Lagisetti, Philip M. Potter, Lidia C. Sambucetti, Stefan Stamm, and Thomas R. Webb

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An Extended Polyanion Activation Surface in Insulin Degrading Enzyme, Eun Suk Song, Mehmet Ozbil, Tingting Zhang, Michael Sheetz, David Lee, Danny Tran, Sheng Li, Rajeev Prabhakar, Louis B. Hersh, and David W. Rodgers

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Clinical Significance of the Integrin α6β4 in Human Malignancies, Rachel L Stewart and Kathleen L O'Connor

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Epithelial Neoplasia Coincides with Exacerbated Injury and Fibrotic Response in the Lungs of Gprc5a-Knockout Mice Following Silica Exposure, Xiaofei Wang, Dongliang Xu, Yueling Liao, Shuangshuang Zhong, Hongyong Song, Beibei Sun, Binhua P. Zhou, Jiong Deng, and Baohui Han

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A Less-Biased Analysis of Metalloproteins Reveals Novel Zinc Coordination Geometries, Sen Yao, Robert M. Flight, Eric C. Rouchka, and Hunter N. B. Moseley

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CD151-α3β1 Integrin Complexes are Prognostic Markers of Glioblastoma and Cooperate with EGFR to Drive Tumor Cell Motility and Invasion, Pengcheng Zhou, Sonia Erfani, Zeyi Liu, Changhe Jia, Yecang Chen, Bingwei Xu, Xinyu Deng, Jose E. Alfáro, Li Chen, Dana L. Napier, Michael Lu, Jian-An Huang, Chunming Liu, Olivier Thibault, Rosalind Segal, Binhua P. Zhou, Natasha Kyprianou, Craig Horbinski, and Xiuwei H. Yang

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Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network, Jieqing Zhu, Gaofeng Xiong, Hanjiang Fu, B. Mark Evers, Binhua P. Zhou, and Ren Xu

Submissions from 2014

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CD151-α3β1 Integrin Complexes Suppress Ovarian Tumor Growth by Repressing Slug-Mediated EMT and Canonical Wnt Signaling, Lauren A. Baldwin, John T. Hoff, Jason Lefringhouse, Michael Zhang, Changhe Jia, Zeyi Liu, Sonia Erfani, Hongyan Jin, Mei Xu, Qing-Bai She, John R. Van Nagell Jr., Chi Wang, Li Chen, Rina Plattner, David M. Kaetzel, Jia Luo, Michael Lu, Dava West, Chunming Liu, Fred R. Ueland, Ronny Drapkin, Binhua P. Zhou, and Xiuwei H. Yang

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Expression, Purification and Characterization of Soluble Red Rooster Laforin as a Fusion Protein in Escherichia Coli, M. Kathryn Brewer, Satrio Husodo, Vikas V. Dukhande, Mary Beth Johnson, and Matthew S. Gentry

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mTORC2 is Required for Rit-Mediated Oxidative Stress Resistance, Weikang Cai and Douglas A. Andres

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Use of Synthetic Isoprenoids to Target Protein Prenylation and Rho GTPases in Breast Cancer Invasion, Min Chen, Teresa Knifley, Thangaiah Subramanian, H. Peter Spielmann, and Kathleen L. O'Connor

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Sudemycin E Influences Alternative Splicing and Changes Chromatin Modifications, Paolo Convertini, Manli Shen, Philip M. Potter, Gustavo Palacios, Chandraiah Lagisetti, Pierre de la Grange, Craig Horbinski, Yvonne N. Fondufe-Mittendorf, Thomas R. Webb, and Stefan Stamm

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FUsed in Sarcoma is a Novel Regulator of Manganese Superoxide Dismutase Gene Transcription, Sanjit Kumar Dhar, Jiayu Zhang, Jozsef Gal, Yong Xu, Lu Miao, Bert C. Lynn, Haining Zhu, Edward J. Kasarskis, and Daret K. St. Clair

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Transcription of the Streptococcus Pyogenes Hyaluronic Acid Capsule Biosynthesis Operon is Regulated by Previously Unknown Upstream Elements, Marina Falaleeva, Oliwia W. Zurek, Robert L. Watkins, Robert W. Reed, Hadeel Ali, Paul Sumby, Jovanka M. Voyich, and Natalia Korotkova

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Repair of O6-Methylguanine Adducts in Human Telomeric G-Quadruplex DNA by O6-Alkylguanine-DNA Alkyltransferase, Lance M. Hellman, Tyler J. Spear, Colton J. Koontz, Manana Melikishvili, and Michael G. Fried

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Novel Pharmacologic Targeting of Tight Junctions and Focal Adhesions in Prostate Cancer Cells, Patrick J. Hensley, Andreas Desiniotis, Chi Wang, Arnold J. Stromberg, Ching-Shih Chen, and Natasha Kyprianou

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HUWE1 is a Molecular Link Controlling RAF-1 Activity Supported by the Shoc2 Scaffold, Eun Ryoung Jang, Ping Shi, Jamal Bryant, Jing Chen, Vikas Dukhande, Matthew S. Gentry, HyeIn Jang, Myoungkun Jeoung, and Emilia Galperin

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Hedgehog-Regulated Atypical PKC Promotes Phosphorylation and Activation of Smoothened and Cubitus Interruptus in Drosophila, Kai Jiang, Yajuan Liu, Junkai Fan, Garretson Epperly, Tianyan Gao, Jin Jiang, and Jianhang Jia

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A Tale of Two Trials: The Impact of 5α-Reductase Inhibition on Prostate Cancer (Review), John M. Lacy and Natasha Kyprianou

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EGFR Phosphorylates and Inhibits Lung Tumor Suppressor GPRC5A in Lung Cancer, Xiaofeng Lin, Shuangshuang Zhong, Xiaofeng Ye, Yueling Liao, Feng Yao, Xiaohua Yang, Beibei Sun, Jie Zhang, Qi Li, Yong Gao, Yifan Wang, Jingyi Liu, Baohui Han, Y. Eugene Chin, Binhua P. Zhou, and Jiong Deng