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Submissions from 2012

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Localization and Functional Characterization of the Rat Oatp4c1 Transporter in an In Vitro Cell System and Rat Tissues, Kuei-Ling Kuo, Haining Zhu, Patrick J. McNamara, and Markos Leggas

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Lesion-Specific DNA-Binding and Repair Activities of Human O⁶-Alkylguanine DNA Alkyltransferase, Manana Melikishvili and Michael G. Fried

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FUS-NLS/Transportin 1 complex structure provides insights into the nuclear targeting mechanism of FUS and the implications in ALS, Chunyan Niu, Jiayu Zhang, Feng Gao, Liuqing Yang, Minze Jia, Haining Zhu, and Weimin Gong

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Integrin α6β4 Cooperates with LPA Signaling to Stimulate Rac through AKAP-Lbc-mediated RhoA Activation, Kathleen L. O'Connor, Min Chen, and L. Nicole Towers

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Integrin α6β4 Cooperates with LPA Signaling to Stimulate Rac Through AKAP-Lbc-Mediated RhoA Activation, Kathleen L. O'Connor, Min Chen, and L. Nicole Towers

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Mechanism of Selective VEGF-A Binding by Neuropilin-1 Reveals a Basis for Specific Ligand Inhibition, Matthew W. Parker, Ping Xu, Hou-Fu Guo, and Craig W. Vander Kooi

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Structural Basis for Activation of Calcineurin by Calmodulin, Julie Rumi-Masante, Farai I. Rusinga, Terrence E. Lester, Tori B. Dunlap, Todd D. Williams, A. Keith Dunker, David D. Weis, and Trevor P. Creamer

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Active Site Mutations Change the Cleavage Specificity of Neprilysin., Travis Sexton, Lisa J. Hitchcook, David W. Rodgers, Luke H. Bradley, and Louis B. Hersh

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Beyond Anchoring: The Expanding Role of the Hendra Virus Fusion Protein Transmembrane Domain in Protein Folding, Stability, and Function, Everett Clinton Smith, Megan R. Culler, Lance M. Hellman, Michael G. Fried, Trevor P. Creamer, and Rebecca Ellis Dutch

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Role of Sequence and Structure of the Hendra Fusion Protein Fusion Peptide in Membrane Fusion, Everett Clinton Smith, Sonia M. Gregory, Lukas K. Tamm, Trevor P. Creamer, and Rebecca Ellis Dutch

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Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation, Eun Suk Song, Manana Melikishvili, Michael G. Fried, Maria A. Juliano, Luiz Juliano, David W. Rodgers, and Louis B. Hersh

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C6 Pyridinium Ceramide Influences Alternative Pre-mRNA Splicing by Inhibiting Protein Phosphatase-1, Chiranthani Sumanasekera, Olga Kelemen, Monique Beullens, Brandon E. Aubol, Joseph A. Adams, Manjula Sunkara, Andrew J. Morris, Mathieu Bollen, Athena Andreadis, and Stefan Stamm

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Cooperative Cluster Formation, DNA Bending and Base-Flipping by O6-Alkylguanine-DNA Alkyltransferase, Ingrid Tessmer, Manana Melikishvili, and Michael G. Fried

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β-Secretases, Alzheimer's Disease, and Down Syndrome, Robin L. Webb and M. Paul Murphy

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Molecular characterization of the viaB locus encoding the biosynthetic machinery for Vi capsule formation in Salmonella Typhi, Michael Wetter, David Goulding, Derek Pickard, Michael Kowarik, Charles J. Waechter, Gordon Dougan, and Michael Wacker

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Medicinal Plants: A Public Resource for Metabolomics and Hypothesis Development, Eve Syrkin Wurtele, Joe Chappell, A. Daniel Jones, Mary Dawn Celiz, Nick Ransom, Manhoi Hur, Ludmila Rizshsky, Matthew Crispin, Philip Dixon, Jia Liu, Mark P. Widrlechner, and Basil J. Nikolau

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USP8 Promotes Smoothened Signaling by Preventing Its Ubiquitination and Changing Its Subcellular Localization, Ruohan Xia, Hongge Jia, Junkai Fan, Yajuan Liu, and Jianhang Jia

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Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS, Ruohan Xia, Yajuan Liu, Liuqing Yang, Jozsef Gal, Haining Zhu, and Jianhang Jia

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Krüppel-like Factor 4 Regulates Intestinal Epithelial Cell Morphology and Polarity, Tianxin Yu, Xi Chen, Wen Zhang, Juan Li, Ren Xu, Timothy C Wang, Walden Ai, and Chunming Liu

Submissions from 2011

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An Evolutionarily Conserved Rit GTPase-p38 MAPK Signaling Pathway Mediates Oxidative Stress Resistance, Weikang Cai, Jennifer L. Rudolph, Susan M. W. Harrison, Ling Jin, Aubrey L. Frantz, Douglas A. Harrison, and Douglas A. Andres

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Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened, Yongbin Chen, Noriaki Sasai, Guoqiang Ma, Tao Yue, Jianhang Jia, James Briscoe, and Jin Jiang

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Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH, Perry A. Christian, Michael V. Fiandalo, and Steven R. Schwarze

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Laforin, a dual specificity phosphatase involved in Lafora disease, is present mainly as monomeric form with full phosphatase activity, Vikas V. Dukhande, Devin M. Rogers, Carlos Romá-Mateo, Jordi Donderis, Alberto Marina, Adam O. Taylor, Pascual Sanz, and Matthew S. Gentry

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mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways, Pat Gulhati, Kanika A. Bowen, Jianyu Liu, Payton D. Stevens, Piotr G. Rychahou, Min Chen, Eun Y. Lee, Heidi L. Weiss, Kathleen L. O'Connor, Tianyan Gao, and B. Mark Evers

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Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation., Kenneth D Harrison, Eon Joo Park, Ningguo Gao, Andrew Kuo, Jeffrey S. Rush, Charles J Waechter, Mark A Lehrman, and William C Sessa