Archived
This content is available here strictly for research, reference, and/or recordkeeping and as such it may not be fully accessible. If you work or study at University of Kentucky and would like to request an accessible version, please use the SensusAccess Document Converter.
US Patent Number
6897200
Publication Date
5-24-2005
Abstract
Camptothecin drugs are stabilized in their antitumor active lactone form by complexation with an oligonucleotide including RNA or catalytic RNA. The oligonucleotide-camptothecin drug complex may be incorporated within a macromolecular assembly including both viral and non-viral oligonucleotide vectors. The invention allows combination gene and camptothecin drug therapy.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
09/807,332
Filing Date
10/14/1998
Recommended Citation
Burke, Thomas; Demir, Ayhan S.; Chavan, Ashok J.; and Yang, Danzhou, "Oligonucleotide Delivery Systems for Camptothecins" (2005). Pharmaceutical Sciences Faculty Patents. 80.
https://uknowledge.uky.edu/ps_patents/80
