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Theses/Dissertations from 2021

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TOWARDS A HOLISTIC RISK MODEL FOR SAFEGUARDING THE PHARMACEUTICAL SUPPLY CHAIN: CAPTURING THE HUMAN-INDUCED RISK TO DRUG QUALITY, Heather R. Campbell

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Examining Childhood Outcomes in Neonatal Abstinence Syndrome, Kailyn Conner

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Understanding the Impact of Solvents in Oral Solid Dosage Formulation and Process Development, Matthew Kyle Defrese

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IDENTIFICATION AND CHARACTERIZATION OF EPITOPE SPECIFIC IMMUNE RESPONSES IN HUMANS AND MICE, David Henson

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HUMAN REGULATORY T CELLS CONTROL INFLAMMATION FROM EFFECTOR T CELLS IN PREDIABETES, Rui Liu

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Pharmacist Provision of Contraception Services in Kentucky: Opinions and Policy Interventions, Dustin K. Miracle

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INVESTIGATION OF THE BIOSYNTHESIS OF THE NUCLEOSIDE ANTIBIOTIC SPHAERIMICIN, Jonathan Overbay

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ABC TRANSPORTERS IN GLIOBLASTOMA: ANTICANCER DRUG TRANSPORT AND TRANSPORTER REGULATION AT THE BLOOD-BRAIN BARRIER, Julia A. Schulz

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ELUCIDATING THE ROLE OF THE TYROSINE PHOSPHATASE, SHP-2, IN REGULATION OF PD-L1 EXPRESSION IN NON-SMALL LUNG CANCER USING BOTH BIOCHEMICAL ANALYSES AND REAL-WORLD GENOMIC INFORMATION, Keller Toral

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INTERACTIONS OF POST-PKS ENZYMES OF THE MITHRAMYCIN BIOSYNTHETIC PATHWAY, Ryan Wheeler

Theses/Dissertations from 2020

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Correlating the Physicochemical Properties of Magnesium Stearate with Tablet Dissolution and Lubrication, Julie L. Calahan

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NOVEL SMALL MOLECULE ANTIFUNGALS FOR INVASIVE FUNGAL INFECTIONS, Emily Dennis

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COMBINATION OF INVESTIGATIONAL CELL-BASED THERAPY AND DEEP BRAIN STIMULATION TO ALTER THE PROGRESSION OF PARKINSON’S DISEASE, Nader El Seblani

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EXTENSIVELY DRUG-RESISTANT PSEUDOMONAS AERUGINOSA IN VITRO SUSCEPTIBILITY AND MECHANISMS OF RESISTANCE, Chanah Gallagher

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THE IMPACT OF BONE MARROW TRANSPLANTION ON PATIENTS WITH PSYCHIATRIC DIAGNOSES: MEDICATION ADHERENCE ASSESSMENT, Brittany Galop

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ELUCIDATING MOLECULAR FUNCTION OF MITHRAMYCIN AND ANALOGUES FOR THE TREATMENT OF EWS-ETS EXPRESSING CANCERS, Reiya Hayden

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Relationship Between Initial Prescription Opioid Exposure Length and Future Opioid Use Disorder Diagnosis in Opioid Naive Adolescents, Eric Lindahl

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Characterization and Engineering of Interrupted Adenylation Domains, Taylor A. Lundy

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Meaningful Measurement Matters: Defining Potentially Inappropriate Medication Use to Target Cognitive Outcomes, Ashley I. Martinez

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ANTIRESORPTIVE BONE THERAPY USE IN ADVANCED LUNG CANCER AND ASSOCIATED OUTCOMES, Noor Naffakh

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POPULATION PHARMACOKINETIC MODELING AND GENETIC ASSOCIATION ANALYSIS IN INFANTS WITH NEONATAL ABSTINENCE SYNDROME RECEIVING MORPHINE OR CLONIDINE, Fei Tang

Theses/Dissertations from 2019

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DEVELOPMENT OF MITHRAMYCIN ANALOGUES WITH IMPROVED EFFICACY AND REDUCED TOXICITY FOR TREATMENT OF ETS-DEPENDENT TUMORS IN EWING SARCOMA AND PROSTATE CANCER, Joseph Michael Eckenrode

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MECHANISMS AND THERMODYNAMICS OF THE INFLUENCE OF SOLUTION-STATE INTERACTIONS BETWEEN HPMC AND SURFACTANTS ON MIXED ADSORPTION ONTO MODEL NANOPARTICLES, Salin Gupta Patel

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DEVELOPING A WORKFLOW TO EVALUATE MEDICATIONS FOR REPURPOSING USING HEALTH CLAIMS DATA: APPLICATION TO SUBSTANCE USE DISORDERS, Emily Ruth Hankosky

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TOWARD AN ENZYME-COUPLED, BIOORTHOGONAL PLATFORM FOR METHYLTRANSFERASES: PROBING THE SPECIFICITY OF METHIONINE ADENOSYLTRANSFERASES, Tyler D. Huber