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Theses/Dissertations from 2020

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EXTENSIVELY DRUG-RESISTANT PSEUDOMONAS AERUGINOSA IN VITRO SUSCEPTIBILITY AND MECHANISMS OF RESISTANCE, Chanah Gallagher

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THE IMPACT OF BONE MARROW TRANSPLANTION ON PATIENTS WITH PSYCHIATRIC DIAGNOSES: MEDICATION ADHERENCE ASSESSMENT, Brittany Galop

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Relationship Between Initial Prescription Opioid Exposure Length and Future Opioid Use Disorder Diagnosis in Opioid Naive Adolescents, Eric Lindahl

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Meaningful Measurement Matters: Defining Potentially Inappropriate Medication Use to Target Cognitive Outcomes, Ashley I. Martinez

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ANTIRESORPTIVE BONE THERAPY USE IN ADVANCED LUNG CANCER AND ASSOCIATED OUTCOMES, Noor Naffakh

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POPULATION PHARMACOKINETIC MODELING AND GENETIC ASSOCIATION ANALYSIS IN INFANTS WITH NEONATAL ABSTINENCE SYNDROME RECEIVING MORPHINE OR CLONIDINE, Fei Tang

Theses/Dissertations from 2019

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DEVELOPMENT OF MITHRAMYCIN ANALOGUES WITH IMPROVED EFFICACY AND REDUCED TOXICITY FOR TREATMENT OF ETS-DEPENDENT TUMORS IN EWING SARCOMA AND PROSTATE CANCER, Joseph Michael Eckenrode

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MECHANISMS AND THERMODYNAMICS OF THE INFLUENCE OF SOLUTION-STATE INTERACTIONS BETWEEN HPMC AND SURFACTANTS ON MIXED ADSORPTION ONTO MODEL NANOPARTICLES, Salin Gupta Patel

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DEVELOPING A WORKFLOW TO EVALUATE MEDICATIONS FOR REPURPOSING USING HEALTH CLAIMS DATA: APPLICATION TO SUBSTANCE USE DISORDERS, Emily Ruth Hankosky

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TOWARD AN ENZYME-COUPLED, BIOORTHOGONAL PLATFORM FOR METHYLTRANSFERASES: PROBING THE SPECIFICITY OF METHIONINE ADENOSYLTRANSFERASES, Tyler D. Huber

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CARBAPENEM-RESISTANT ENTEROBACTERIACEAE: EPIDEMIOLOGY, GENETICS, IN VITRO ACTIVITY, AND PHARMACODYNAMIC MODELING, Brandon Kulengowski

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INVESTIGATION OF FACTORS INFLUENCING PROTEIN STABILITY IN LYOPHILIZED FORMULATIONS USING SOLID-STATE NMR SPECTROSCOPY, Ashley Lay-Fortenbery

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THE DEVELOPMENT OF NOVEL PROTEASOME INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA AND ALZHEIMER’S DISEASE, Min Jae Lee

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DISCOVERY OF NOVEL PHARMACOTHERAPEUTICS FOR SUBSTANCE USE DISORDERS, Na-Ra Lee

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ACTINOMYCIN FAMILIAL DIVERSITY DRIVEN BY PHENOXAZINONE-CORE REACTIVITY, Matthew Richard McErlean

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PHASE BEHAVIOR OF AMORPHOUS SOLID DISPERSIONS: MISCIBILITY AND MOLECULAR INTERACTIONS, Kanika Sarpal

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Trends and Patterns in Use of Medications for Opioid Use Disorder in a Commercially Insured Population in the U.S., Catherine Serratore

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THERAPEUTIC VIDEO GAMES AND THE SIMULATION OF EXECUTIVE FUNCTION DEFICITS IN ADHD, Markus Tiitto

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Pharmacokinetic and Pharmacodynamic Evaluation of Cocaine Hydrolases for the Treatment of Cocaine Overdose and Cocaine Addiction Using Rodent Models, Xirong Zheng

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COMPUTATIONAL MODELING GUIDED DISCOVERY OF NOVEL INHIBITORS OF MPGES-1 AND BUTYRYLCHOLINESTERASE AS DRUG CANDIDATES, Shuo Zhou

Theses/Dissertations from 2018

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DISCOVERY OF NOVEL MURAYMYCIN ANTIBIOTICS AND INSIGHT INTO THE BIOSYNTHETIC PATHWAY, Zheng Cui

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USING THE QBEST EQUATION TO EVALUATE ELLAGIC ACID SAFETY DATA: GENERATING A QNOAEL WITH CONFIDENCE LEVELS FROM DISPARATE LITERATURE, Cynthia Rose Dickerson

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EXPLORING THE EFFECT OF CHRONIC INFLAMMATION ON RESPONSE TO IMMUNE CHECKPOINT INHIBITORS IN CANCER, Sherif M. El-Refai

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ALTERNATIVELY ACTIVATED MACROPHAGES IN PSEUDOMONAS AERUGINOSA PNEUMONIA: MODULATION OF THE NF-ΚB SIGNALING PATHWAY AND THE IMMUNOMODULATORY ROLE OF ARGINASE-1, Dalia Haydar

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DISCOVERY OF NEW ANTIMICROBIAL OPTIONS AND EVALUATION OF AMINOGLYCOSIDE RESISTANCE ENZYME-ASSOCIATED RESISTANCE EPIDEMIC, Selina Y. L. Holbrook