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Submissions from 2021

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The Context-Dependent Impact of Integrin-Associated CD151 and Other Tetraspanins on Cancer Development and Progression: A Class of Versatile Mediators of Cellular Function and Signaling, Tumorigenesis and Metastasis, Sonia F. Erfani, Hui Hua, Yueyin Pan, Binhua P. Zhou, and Xiuwei H. Yang

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Innate Immune Activation by Checkpoint Inhibition in Human Patient-Derived Lung Cancer Tissues, Teresa W. M. Fan, Richard M. Higashi, Huan Song, Saeed Daneshmandi, Angela L. Mahan, Matthew S. Purdom, Therese J. Bocklage, Thomas A. Pittman, Daheng He, Chi Wang, and Andrew N. Lane

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Through the Lens: Youth Experiences with Cancer in Rural Appalachian Kentucky Using Photovoice, Katie Gaines, Courtney Martin, Chris Prichard, and Nathan L. Vanderford

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Association between Obesity and Histological Tumor Budding in Patients with Nonmetastatic Colon Cancer, Tong Gan, Kurt B. Schaberg, Daheng He, Akila Mansour, Harit Kapoor, Chi Wang, B. Mark Evers, and Therese J. Bocklage

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Protocol for Rapid Assessment of the Efficacy of Novel Wnt Inhibitors Using Zebrafish Models, Meghan G. Haney, Mary Wimsett, Chunming Liu, and Jessica S. Blackburn

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KEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung Cancer, Kristen S. Hill, Anthony McDowell Jr., J. Robert McCorkle, Erin Schuler, Sally R. Ellingson, Rina Plattner, and Jill M. Kolesar

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Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK–SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue, Terry D. Hinds, Jr.; Zachary A. Kipp; Mei Xu; Frederique B. Yiannikouris; Andrew J. Morris; Donald F. Stec; Walter Wahli; and David E. Stec

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The Use of a Book Club to Promote Biomedical Trainee Professional Development, Jenni Ho, Stacy E. Smith, Erin J. Oakley, and Nathan L. Vanderford

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Real-World Evaluation of Universal Germline Screening for Cancer Treatment-Relevant Pharmacogenes, Megan L. Hutchcraft, Nan Lin, Shulin Zhang, Catherine Sears, Kyle Zacholski, Elizabeth A. Belcher, Eric B. Durbin, John L. Villano, Michael J. Cavnar, Susanne M. Arnold, Frederick R. Ueland, and Jill M. Kolesar

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Androgen Receptor Signaling in Prostate Cancer and Therapeutic Strategies, Aasems Jacob, Rishi Raj, Derek B. Allison, and Zin W. Myint

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Real World Clinicopathologic Observations of Patients with Metastatic Solid Tumors Receiving Immune Checkpoint Inhibitor Therapy: Analysis from Kentucky Cancer Registry, Aasems Jacob, Jianrong Wu, Jill M. Kolesar, Eric B. Durbin, Aju Mathew, Susanne Arnold, and Aman Chauhan

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Hierarchical Harmonization of Atom-Resolved Metabolic Reactions across Metabolic Databases, Huan Jin and Hunter N. B. Moseley

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Role of AMPK and Akt in Triple Negative Breast Cancer Lung Colonization, Jeremy Johnson, Zeta Chow, Eun Young Lee, Heidi L. Weiss, B. Mark Evers, and Piotr G. Rychahou

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Development of a Multilevel Intervention to Increase Colorectal Cancer Screening in Appalachia, Aaron J. Kruse-Diehr, Jill M. Oliveri, Robin C. Vanderpool, Mira L. Katz, Paul L. Reiter, Darrell M. Gray II, Michael L. Pennell, Gregory S. Young, Bin Huang, Darla Fickle, Mark Cromo, Melinda Rogers, David Gross, Ashley Gibson, Jeanne Jellison, Michael D. Sarap, Tonia A. Bivens, Tracy D. McGuire, Ann Scheck McAlearney, Timothy R. Huerta, Saurabh Rahurkar, Electra D. Paskett, and Mark B. Dignan

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Clinical Outcomes of Molecular Tumor Boards: A Systematic Review, Kara L. Larson, Bin Huang, Heidi L. Weiss, Pamela C. Hull, Philip M. Westgate, Rachel W. Miller, Susanne M. Arnold, and Jill M. Kolesar

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Genome-Wide Association Meta-Analysis Identifies Pleiotropic Risk Loci for Aerodigestive Squamous Cell Cancers, Corina Lesseur, Aida Ferreiro-Iglesias, James D. McKay, Yohan Bossé, Mattias Johansson, Valerie Gaborieau, Maria Teresa Landi, David C. Christiani, Neil C. Caporaso, Stig E. Bojesen, Christopher I. Amos, Sanjay Shete, Geoffrey Liu, Gadi Rennert, Demetrius Albanes, Melinda C. Aldrich, Adonina Tardon, Chu Chen, Liloglou Triantafillos, John K. Field, and Susanne Arnold

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DNA Repair Pathways in Cancer Therapy and Resistance, Lan-ya Li, Yi-di Guan, Xi-sha Chen, Jin-ming Yang, and Yan Cheng

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Bone in the Breast: A Case Report of a Metaplastic Breast Cancer with Osseous Differentiation, Kyle Luo and Xiaoqin Wang

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Gender Differences in Urothelial Bladder Cancer: Effects of Natural Killer Lymphocyte Immunity, Charles T. Lutz, Lydia Livas, Steven R. Presnell, Morgan Sexton, and Peng Wang

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RORα Suppresses Cancer-Associated Inflammation by Repressing Respiratory Complex I-Dependent ROS Generation, Wei Mao, Gaofeng Xiong, Yuanyuan Wu, Chi Wang, Daret St. Clair, Jai-Da Li, and Ren Xu

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Lapatinib and Poziotinib Overcome ABCB1-Mediated Paclitaxel Resistance in Ovarian Cancer, J. Robert McCorkle, Justin W. Gorski, Jinpeng Liu, McKayla J. Riggs, Anthony B. McDowell Jr., Nan Lin, Chi Wang, Frederick R. Ueland, and Jill M. Kolesar

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Preclinical Evaluation of Artesunate as an Antineoplastic Agent in Ovarian Cancer Treatment, Anthony McDowell Jr., Kristen S. Hill, Joseph Robert McCorkle, Justin W. Gorski, Yilin Zhang, Ameen A. Salahudeen, Frederick R. Ueland, and Jill M. Kolesar

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Untargeted Lipidomics of Non-Small Cell Lung Carcinoma Demonstrates Differentially Abundant Lipid Classes in Cancer vs. Non-Cancer Tissue, Joshua M. Mitchell, Robert M. Flight, and Hunter N. B. Moseley

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A Case Report of Metastatic Castration-Resistant Prostate Cancer Harboring a PTEN Loss, Zin W. Myint, Derek B. Allison, and Carleton S. Ellis

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Evaluation of Glutaminase Expression in Prostate Adenocarcinoma and Correlation with Clinicopathologic Parameters, Zin W. Myint, Ramon C. Sun, Patrick J. Hensley, Andrew C. James, Peng Wang, Stephen E. Strup, Robert J. McDonald, Donglin Yan, William H. St. Clair, and Derek B. Allison