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Submissions from 2021

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Characterizing Long COVID: Deep Phenotype of a Complex Condition, Rachel R. Deer, Madeline A. Rock, Nicole Vasilevsky, Leigh Carmody, Halie Rando, Alfred J. Anzalone, Marc D. Basson, Tellen D. Bennett, Timothy Bergquist, Eilis A. Boudreau, Carolyn T. Bramante, James Brian Byrd, Tiffany J. Callahan, Lauren E. Chan, Haitao Chu, Christopher G. Chute, Ben D. Coleman, Hannah E. Davis, Joel Gagnier, Casey S. Greene, and Ramakanth Kavuluru

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Dual-Functional Phosphorene Nanocomposite Membranes for the Treatment of Perfluorinated Water: An Investigation of Perfluorooctanoic Acid Removal via Filtration Combined with Ultraviolet Irradiation or Oxygenation, Joyner Eke, Lillian Banks, M. Abdul Mottaleb, Andrew J. Morris, Olga V. Tsyusko, and Isabel C. Escobar

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Sex Differences in Trends and In-Hospital Outcomes among Patients with Critical Limb Ischemia: A Nationwide Analysis, Ayman Elbadawi, Kirolos Barssoum, Michael Megaly, Devesh Rai, Ahmed Elsherbeeny, Hend Mansoor, Mehdi H. Shishehbor, Ahmed K. Abdel-Latif, Martha Gulati, and Islam Y. Elgendy

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A Step-by-Step Guide to Implementing a Multidisciplinary Endocarditis Team, Sami El-Dalati, Daniel Cronin, James Riddell, Michael Shea, Richard L. Weinberg, Emily Stoneman, Twisha Patel, Kirra Ressler, and George Michael Deeb

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Innate Immune Activation by Checkpoint Inhibition in Human Patient-Derived Lung Cancer Tissues, Teresa W. M. Fan, Richard M. Higashi, Huan Song, Saeed Daneshmandi, Angela L. Mahan, Matthew S. Purdom, Therese J. Bocklage, Thomas A. Pittman, Daheng He, Chi Wang, and Andrew N. Lane

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APOΕ4 Lowers Energy Expenditure in Females and Impairs Glucose Oxidation by Increasing Flux through Aerobic Glycolysis, Brandon C. Farmer, Holden C. Williams, Nicholas A. Devanney, Margaret A. Piron, Grant K. Nation, David J. Carter, Adeline E. Walsh, Rebika Khanal, Lyndsay E. A. Young, Jude C. Kluemper, Gabriela Hernandez, Elizabeth J. Allenger, Rachel Mooney, Lesley R. Golden, Cathryn T. Smith, J. Anthony Brandon, Vedant A. Gupta, Philip A. Kern, Matthew S. Gentry, Josh M. Morganti, Ramon C. Sun, and Lance A. Johnson

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Macrophages Expressing Uncoupling Protein 1 Increase in Adipose Tissue in Response to Cold in Humans, Brian S. Finlin, Hasiyet Memetimin, Amy L. Confides, Beibei Zhu, Philip M. Westgate, Esther E. Dupont-Versteegden, and Philip A. Kern

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Serum Renin and Major Adverse Kidney Events in Critically Ill Patients: A Multicenter Prospective Study, Alexander H. Flannery, Victor M. Ortiz-Soriano, Xilong Li, Fabiola G. Gianella, Robert D. Toto, Orson W. Moe, Prasad Devarajan, Stuart L. Goldstein, and Javier A. Neyra

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Efficacy and Safety of Vancomycin Loading Doses in Critically Ill Patients with Methicillin-Resistant Staphylococcus aureus Infection, Alexander H. Flannery, Katie L. Wallace, Christian N. Rhudy, Allison S. Olmsted, Rachel C. Minrath, Stuart M. Pope, Aaron M. Cook, David S. Burgess, and Peter E. Morris

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Association between Obesity and Histological Tumor Budding in Patients with Nonmetastatic Colon Cancer, Tong Gan, Kurt B. Schaberg, Daheng He, Akila Mansour, Harit Kapoor, Chi Wang, B. Mark Evers, and Therese J. Bocklage

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Utilizing Patient-Derived Epithelial Ovarian Cancer Tumor Organoids to Predict Carboplatin Resistance, Justin W. Gorski, Zhuwei Zhang, J. Robert McCorkle, Jodi M. DeJohn, Chi Wang, Rachel W. Miller, Holly H. Gallion, Charles S. Dietrich III, Frederick R. Ueland, and Jill M. Kolesar

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5th Generation vs 4th Generation Troponin T in Predicting Major Adverse Cardiovascular Events and All-Cause Mortality in Patients Hospitalized for Non-Cardiac Indications: A Cohort Study, Vedant Gupta, Marc Paranzino, Talal Alnabelsi, Karam Ayoub, Joshua Eason, Andin Mullis, John R. Kotter, Andrew Parks, Levi May, Sethabhisha Nerusu, Chen Dai, Daniel Cleland, Steve W. Leung, and Vincent L. Sorrell

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Hemodynamic Management of Patients with Ejection Fraction < 50% Undergoing Pulmonary Vein Ablation, Aaron B. Hesselson and Heather Hesselson

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KEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung Cancer, Kristen S. Hill, Anthony McDowell Jr., J. Robert McCorkle, Erin Schuler, Sally R. Ellingson, Rina Plattner, and Jill M. Kolesar

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Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK–SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue, Terry D. Hinds, Jr.; Zachary A. Kipp; Mei Xu; Frederique B. Yiannikouris; Andrew J. Morris; Donald F. Stec; Walter Wahli; and David E. Stec

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Perspectives on Extended-Release Naltrexone Induction among Patients Living with HIV and Opioid Use Disorder: A Qualitative Analysis, Kim A. Hoffman, Robin Baker, Laura C. Fanucchi, Paula J. Lum, Lynn E. Kunkel, Javier Ponce Terashima, Dennis McCarty, Petra Jacobs, and P. Todd Korthuis

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Real-World Evaluation of Universal Germline Screening for Cancer Treatment-Relevant Pharmacogenes, Megan L. Hutchcraft, Nan Lin, Shulin Zhang, Catherine Sears, Kyle Zacholski, Elizabeth A. Belcher, Eric B. Durbin, John L. Villano, Michael J. Cavnar, Susanne M. Arnold, Frederick R. Ueland, and Jill M. Kolesar

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Impact of Patient Load on the Quality of Electronic Medical Record Documentation, Aasems Jacob, Rishi Raj, Sayee Alagusundaramoorthy, Jing Wei, Jianrong Wu, and Margaret Eng

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Androgen Receptor Signaling in Prostate Cancer and Therapeutic Strategies, Aasems Jacob, Rishi Raj, Derek B. Allison, and Zin W. Myint

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Real World Clinicopathologic Observations of Patients with Metastatic Solid Tumors Receiving Immune Checkpoint Inhibitor Therapy: Analysis from Kentucky Cancer Registry, Aasems Jacob, Jianrong Wu, Jill M. Kolesar, Eric B. Durbin, Aju Mathew, Susanne Arnold, and Aman Chauhan

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Novel Fusion KTN1-PRKD1 in Cribriform Adenocarcinoma of Salivary Glands Located in the Parotid Gland: Case Report Including Cytologic Findings, Treeva K. Jassim, T. Sheng, Shulin Zhang, Sainan Wei, Susanne M. Arnold, Alexandra E. Kejner, Therese J. Bocklage, and Julie C. Dueber

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BOOSTing Patient Mobility and Function on a General Medical Unit by Enhancing Interprofessional Care, Audrey M. Johnson, Janice Kuperstein, Rachel Hogg-Graham, Preetham Talari, A. Kelly, and Esther E. Dupont-Versteegden

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Kidney Recovery in Patients with Acute Kidney Injury Treated in Outpatient Hemodialysis or Rehabilitation Facilities, Melissa Jordan, Victor M. Ortiz-Soriano, Aaron Pruitt, Lauren Chism, Lucas J. Liu, Nourhan Chaaban, Madona Elias, B. Peter Sawaya, Jin Chen, and Javier A. Neyra

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A Distinct Difference between Air and Mucosal Temperatures in Human Respiratory Tract, Mehdi Khosravi, Ruei-Lung Lin, Ashish P. Maskey, Subodh Pandey, An-Hsuan Lin, and Lu-Yuan Lee

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Radiopharmaceutical Validation for Clinical Use, Charles A. Kunos, Rodney Howells, Aman Chauhan, Zin W. Myint, Mark E. Bernard, Riham H. El Khouli, and Jacek Capala