Theses/Dissertations from 2020
NOVEL POST-TRANSLATIONAL MODIFICATION AND FUNCTION OF FUS: THE RELEVANCE TO AMYOTROPHIC LATERAL SCLEROSIS, Alexandra Arenas
Prostate Cancer Resistance to Cabazitaxel Chemotherapy, Diane Begemann
Examining the Role of Metabolic Pathways as Therapeutic Modalities for Triple Negative Breast Cancer, Jeremy Andrew Johnson
Theses/Dissertations from 2019
A COMPROMISED LIVER ALTERS PCB TOXICITY AND NUTRIENT METABOLISM, Jazmyne D. L. Barney
MECHANISMS OF TRINUCLEOTIDE REPEAT INSTABILITY DURING DNA SYNTHESIS, Kara Y. Chan
THE ROLE OF NRF2 SIGNALLING IN CELL PROLIFERATION AND TUMORIGENESIS OF CHROMIUM TRANSFORMED HUMAN BRONCHIAL EPITHELIAL CELLS, Marco Antonio de Freitas Clementino
MUTATIONS OF FUS CAUSE AGGREGATION OF RNA BINDING PROTEINS, DISRUPTIONS IN PROTEIN SYNTHESIS, AND DYSREGULATION OF NONSENSE MEDIATED DECAY, Marisa Elizabeth Kamelgarn
MULTIGENERATIONAL GENOMIC AND EPIGENETIC EFFECTS OF MANUFACTURED SILVER NANOMATERIALS IN CAENORHABDITIS ELEGANS, Anye Wamucho
Theses/Dissertations from 2018
TARGETING THE CELLULAR REDOX ENVIRONMENT: A NOVEL APPROACH FOR THE TREATMENT OF HEMATOPOIETIC NEOPLASMS, Dustin W. Carroll
AN OPTIMIZED SOLID-PHASE REDUCTION AND CAPTURE STRATEGY FOR THE STUDY OF REVERSIBLY-OXIDIZED CYSTEINES AND ITS APPLICATION TO METAL TOXICITY, John Andrew Hitron
A NOVEL ROLE FOR THE TUMOR-SUPPRESSOR PAR-4 IN REGULATION OF ADIPOGENESIS AND OBESITY, James Sledziona
MULTIVARIATE ANALYSIS TO IDENTIFY POTENTIAL BIOMARKERS FOR PROGNOSIS AND TREATMENT RESISTANCE IN HEAD AND NECK CANCER PATIENTS, Christina Ann Wicker
ROLE OF OXIDIZED EXTRACELLULAR VESICLES AS EARLY BIOMARKERS AND INFLAMMATORY MEDIATORS IN CHEMOTHERAPY-INDUCED NORMAL TISSUE INJURY, Chontida Yarana
Theses/Dissertations from 2017
NUCLEOTIDE EXCISION REPAIR: IMPACTS OF ENVIRONMENTAL CARCINOGENS AND ITS ROLE IN CANCER SUSCEPTIBILITY IN APPALACHIAN KENTUCKY, Nathaniel C. Holcomb
Theses/Dissertations from 2016
ROLE OF SULFIREDOXIN INTERACTING PROTEINS IN LUNG CANCER DEVELOPMENT, Hedy Chawsheen
Overcoming Treatment Resistance in Heterogeneous Tumors, Nikhil Hebbar
EXPLORATION OF THE SRX-PRX AXIS AS A SMALL-MOLECULE TARGET, Murli Mishra
Theses/Dissertations from 2015
PHARMACOLOGIC INDUCTION OF THE MELANOCOTIN 1 RECEPTOR (MC1R) PATHWAY PROVIDES PROTECTION AGAINST SUNBURN AND ENHANCES EXPRESSION OF ANTIOXIDANT ENZYMES IN THE SKIN, Alexandra Amaro-Ortiz
ROLE OF CAVEOLIN-1 AND NRF2 IN NUTRITIONAL MODULATION OF PCB TOXICITY, Michael C. Petriello
CROSS-TALK BETWEEN THE TUMOR SUPPRESSORS PAR-4 AND P53, Tripti Shrestha Bhattarai