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Submissions from 2021

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Space-Occupying Brain Lesions, Trauma-Related Tau Astrogliopathy, and ARTAG: A Report of Two Cases and a Literature Review, Adam D. Bachstetter, Filip G. Garrett, Gregory A. Jicha, and Peter T. Nelson

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Inflammatory Regulation of CNS Barriers After Traumatic Brain Injury: A Tale Directed by Interleukin-1, Colleen N. Bodnar, James B. Watson, Emma K. Higgins, Ning Quan, and Adam D. Bachstetter

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Differential Leukocyte and Platelet Profiles in Distinct Models of Traumatic Brain Injury, William Brad Hubbard, Meenakshi Banerjee, Hemendra J. Vekaria, Kanakanagavalli Shravani Prakhya, Smita Joshi, Qingjun Wang, Kathryn E. Saatman, Sidney W. Whiteheart, and Patrick G. Sullivan

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Machine Intelligence Identifies Soluble TNFa as a Therapeutic Target for Spinal Cord Injury, J. R. Huie, A. R. Ferguson, N. Kyritsis, J. Z. Pan, K.-A. Irvine, J. L. Nielson, P. G. Schupp, M. C. Oldham, John C. Gensel, A. Lin, M. R. Segal, R. R. Ratan, J. C. Bresnahan, and M. S. Beattie

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Sex Differences in Mitochondrial Function Following a Controlled Cortical Impact Traumatic Brain Injury in Rodents, Olivia J. Kalimon and Patrick G. Sullivan

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The Effects of Myelin on Macrophage Activation Are Phenotypic Specific via cPLA2 in the Context of Spinal Cord Injury Inflammation, Timothy J. Kopper, Bei Zhang, William M. Bailey, Kara E. Bethel, and John C. Gensel

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IGF1-Stimulated Posttraumatic Hippocampal Remodeling Is Not Dependent on mTOR, Erica L. Littlejohn, Anthony J. DeSana, Hannah C. Williams, Rudy T. Chapman, Binoy Joseph, Jelena A. Juras, and Kathryn E. Saatman

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Dysregulation of Systemic Immunity in Aging and Dementia, Jenny Lutshumba, Barbara S. Nikolajczyk, and Adam D. Bachstetter

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Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer’s Disease: A Targeted Transcriptome Analysis, Chao Ma, Jerry B. Hunt, Andrii Kovalenko, Huimin Liang, Maj-Linda B. Selenica, Michael B. Orr, Bei Zhang, John C. Gensel, David J. Feola, Marcia N. Gordon, Dave Morgan, Paula C. Bickford, and Daniel C. Lee

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Arginase 1 Insufficiency Precipitates Amyloid-β Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis, Chao Ma, Jerry B. Hunt, Maj-Linda B. Selenica, Awa Sanneh, Leslie A. Sandusky-Beltran, Mallory Watler, Rana Daas, Andrii Kovalenko, Huimin Liang, Devon Placides, Chuanhai Cao, Xiaoyang Lin, Michael B. Orr, Bei Zhang, John C. Gensel, David J. Feola, Marcia N. Gordon, Dave Morgan, Paula C. Bickford, and Daniel C. Lee

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Macrophage-Engineered Vesicles for Therapeutic Delivery and Bidirectional Reprogramming of Immune Cell Polarization, Khaga R. Neupane, J. Robert McCorkle, Timothy J. Kopper, Jourdan E. Lakes, Surya P. Aryal, Masud Abdullah, Aaron A. Snell, John C. Gensel, Jill M. Kolesar, and Christopher I. Richards

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Genetic Approach to Elucidate the Role of Cyclophilin D in Traumatic Brain Injury Pathology, Ryan D. Readnower, W. Brad Hubbard, Olivia J. Kalimon, James W. Geddes, and Patrick G. Sullivan

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The Giant Axolotl Genome Uncovers the Evolution, Scaling, and Transcriptional Control of Complex Gene Loci, Siegfried Schloissnig, Akane Kawaguchi, Sergej Nowoshilow, Francisco Falcon, Leo Otsuki, Pietro Tardivo, Nataliya Timoshevskaya, Melissa C. Keinath, Jeramiah J. Smith, S. Randal Voss, and Elly M. Tanaka

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Dystrophic Microglia Are Associated with Neurodegenerative Disease and not Healthy Aging in the Human Brain, Ryan K. Shahidehpour, Rebecca E. Higdon, Nicole G. Crawford, Janna H. Neltner, Eseosa T. Ighodaro, Ela Patel, Douglas Price, Peter T. Nelson, and Adam D. Bachstetter

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Acute Inflammatory Profiles Differ with Sex and Age After Spinal Cord Injury, Andrew N. Stewart, John L. Lowe, Ethan P. Glaser, Caitlin A. Mott, Ryan K. Shahidehpour, Katelyn E. McFarlane, William M. Bailey, Bei Zhang, and John C. Gensel

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Mitochondria Exert Age-Divergent Effects on Recovery from Spinal Cord Injury, Andrew N. Stewart, Katelyn E. McFarlane, Hemendra J. Vekaria, William M. Bailey, Stacey A. Slone, Lauren A. Tranthem, Bei Zhang, Samir P. Patel, Patrick G. Sullivan, and John C. Gensel

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Immunomodulatory Effects of Azithromycin Revisited: Potential Applications to COVID-19, Vincent J. Venditto, Dalia Haydar, Ahmed K. Abdel-Latif, John C. Gensel, Michael I. Anstead, Michelle G. Pitts, Jarrod W. Creameans, Timothy J. Kopper, Chi Peng, and David J. Feola

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Temporal Changes in Inflammatory Mitochondria-Enriched MicroRNAs Following Traumatic Brain Injury and Effects of miR-146a Nanoparticle Delivery, Wang-Xia Wang, Pareshkumar Prajapati, Hemendra J. Vekaria, Malinda Spry, Amber L. Cloud, Patrick G. Sullivan, and Joe E. Springer

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MicroRNAs as Biomarkers for Predicting Complications Following Aneurysmal Subarachnoid Hemorrhage, Wang-Xia Wang, Joe E. Springer, and Kevin W. Hatton

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A Highly Predictive MicroRNA Panel for Determining Delayed Cerebral Vasospasm Risk Following Aneurysmal Subarachnoid Hemorrhage, Wang-Xia Wang, Joe E. Springer, Kevin Xie, David W. Fardo, and Kevin W. Hatton

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Inhibition of Bruton Tyrosine Kinase Reduces Neuroimmune Cascade and Promotes Recovery after Spinal Cord Injury, Chen Guang Yu, Vimala Bondada, Hina Iqbal, Kate L. Moore, John C. Gensel, Subbarao Bondada, and James W. Geddes

Submissions from 2020

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Liposomal Delivery of Azithromycin Enhances Its Immunotherapeutic Efficacy and Reduces Toxicity in Myocardial Infarction, Ahmed Al-Darraji, Renée R. Donahue, Himi Tripathi, Hsuan Peng, Bryana M. Levitan, Lakshman Chelvarajan, Dalia Haydar, Erhe Gao, David Henson, John C. Gensel, David J. Feola, Vincent J. Venditto, and Ahmed K. Abdel-Latif

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Microglial-Associated Responses to Comorbid Amyloid Pathology and Hyperhomocysteinemia in an Aged Knock-in Mouse Model of Alzheimer's Disease, David J. Braun, Edgardo R. Dimayuga, Josh M. Morganti, and Linda J. Van Eldik

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Modulation of Epileptogenesis: A Paradigm for the Integration of Enzyme-Based Microelectrode Arrays and Optogenetics, Corwin R. Butler, Jeffery A. Boychuk, Francois Pomerleau, Ramona Alcala, Peter Huettl, Yi Ai, Johan Jakobsson, Sidney W. Whiteheart, Greg A. Gerhardt, Bret N. Smith, and John T. Slevin

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The β3-Adrenergic Receptor Agonist Mirabegron Improves Glucose Homeostasis in Obese Humans, Brian S. Finlin, Hasiyet Memetimin, Beibei Zhu, Amy L. Confides, Hemendra J. Vekaria, Riham H. El Khouli, Zachary R. Johnson, Philip M. Westgate, Jianzhong Chen, Andrew J. Morris, Patrick G. Sullivan, Esther E. Dupont-Versteegden, and Philip A. Kern