Abstract
Fusarium wilt in tobacco caused by the fungus Fusarium oxysporum f. sp. nicotianae is a disease‑management challenge worldwide, as there are few effective and environmentally benign chemical agents for its control. This challenge results in substantial losses in both the quality and yield of tobacco products. Based on an in vitro analysis of the effects of different phenylpropanoid intermediates, we found that the early intermediates trans‑cinnamic acid and para‑coumaric acid effectively inhibit the mycelial growth of F. oxysporum f. sp. nicotianae strain FW316F, whereas the downstream intermediates quercetin and caffeic acid exhibit no fungicidal properties. Therefore, our in vitro screen suggests that trans‑cinnamic acid and para‑coumaric acid are promising chemical agents and natural lead compounds for the suppression of F. oxysporum f. sp. nicotianae growth.
Document Type
Article
Publication Date
2020
Digital Object Identifier (DOI)
https://doi.org/10.5423/PPJ.NT.08.2020.0155
Funding Information
This work was supported by the Kentucky Tobacco Research and Development Center and a Phillip Morris International grant in 2017.
Repository Citation
Shull, Timothy E.; Kurepa, Jasmina; Miller, Robert D.; Martinez-Ochoa, Natalia; and Smalle, Jan A., "Inhibition of Fusarium oxysporum f. sp. nicotianae Growth by Phenylpropanoid Pathway Intermediates" (2020). Plant and Soil Sciences Faculty Publications. 150.
https://uknowledge.uky.edu/pss_facpub/150
Notes/Citation Information
Published in The Plant Pathology Journal, v. 36, no.6.
©The Korean Society of Plant Pathology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.