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US Patent Number

5691365

Publication Date

11-25-1997

Abstract

Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown to competitively inhibit dopamine release induced by nicotine. The nicotine analog compounds are useful in the treatment of nicotine abuse, smoking cessation therapy, as an antidote for nicotine intoxication, treatment of cognitive disorders such as Alzheimer's disease and for the treatment of Parkinson's disease.

Assignees

University of Kentucky Research Foundation, Lexington, Ky.

Application Number

503,904

Filing Date

07/18/1995

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