US Patent Number
5691365
Publication Date
11-25-1997
Abstract
Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown to competitively inhibit dopamine release induced by nicotine. The nicotine analog compounds are useful in the treatment of nicotine abuse, smoking cessation therapy, as an antidote for nicotine intoxication, treatment of cognitive disorders such as Alzheimer's disease and for the treatment of Parkinson's disease.
Assignees
University of Kentucky Research Foundation, Lexington, Ky.
Application Number
503,904
Filing Date
07/18/1995
Recommended Citation
Crooks, Peter A.; Dwoskin, Linda P.; and Ravard, Alain, "Nicotinic Receptor Antagonists in the Treatment of Neuropharmacological Disorders" (1997). Pharmaceutical Sciences Faculty Patents. 96.
https://uknowledge.uky.edu/ps_patents/96