US Patent Number
5672359
Publication Date
9-30-1997
Abstract
The present invention relates to a hard capsule made from a material such as gelatin, starch or a hydrophilic polymer. The capsule of the present invention is formulated into a delivery system which incorporates pharmacologically active components in three or more distinct compartments. When three compartments are utilized in the capsule, the outer compartment incorporates a drug and excipients into a layer which coats the outer part of the capsule. This layer represents the rapid release portion of the delivery system. The intermediate compartment comprises a powder formulation comprised of a drug and excipients which represents the intermediary speed release portion of the delivery system. The innermost compartment incorporates the active ingredient or ingredients in a multiparticulate form, such as small pellets, and represents the slow release component of the delivery system.
Assignees
University of Kentucky Research Foundation, Lexington, Ky.
Application Number
560,946
Filing Date
11/20/1995
Recommended Citation
Digenis, George and Noskova, Dagmar, "Multicompartment Hard Capsule with Control Release Properties" (1997). Pharmaceutical Sciences Faculty Patents. 89.
https://uknowledge.uky.edu/ps_patents/89
