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US Patent Number
5456908
Publication Date
10-10-1995
Abstract
Novel classes of inhibitors which selectively inhibit the cellular transport of normally transported substances, specifically polyamines are taught which comprise (i) polymers of the transported substance or (ii) protein or polypeptide conjugates of the transported substance. These inhibitors may be used in vitro to assess the effect of the transported substance on cellular functions and in vivo for treating disease conditions involving transport of the particular substance, e.g., a polyamine.
Assignees
University of Kentucky Research Foundation, Lexington, Ky.
Application Number
203,629
Filing Date
03/01/1994
Recommended Citation
Aziz, Shewan M. and Gillespie, Mark N., "Polyamine-Polyamine and Polyamine-Protein Transport Inhibitor Conjugates and Their Use as Pharmaceuticals and in Research Relating to Polyamine Transport" (1995). Pharmaceutical Sciences Faculty Patents. 85.
https://uknowledge.uky.edu/ps_patents/85
