Chain-Modified Pyridino-N Substituted Nicotine Compounds for Use in the Treatment of CNS Pathologies
US Patent Number
7091357
Publication Date
8-15-2006
Abstract
Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, addiction to opiates, addiction to alcohol, addiction to tobacco products, addiction to nicotine, schizophrenia and related diseases, depression and related conditions, Alzheimer's disease, Parkinson's disease, irritable bowel syndrome, and colitis. The compounds competitively inhibit central nervous system acting nicotinic receptor agonists and act at the putative α3β2* and α4β2 neuronal nicotinic receptors in the central nervous system.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
10/328,192
Filing Date
12/26/2002
Recommended Citation
Crooks, Peter A.; Dwoshin, Linda; Xu, Rui; and Ayers, Joshua T., "Chain-Modified Pyridino-N Substituted Nicotine Compounds for Use in the Treatment of CNS Pathologies" (2006). Pharmaceutical Sciences Faculty Patents. 45.
https://uknowledge.uky.edu/ps_patents/45
