US Patent Number
7759468
Publication Date
7-20-2010
Abstract
A method for preparing a site-specific peptide probe, wherein the peptide is specific to a receptor, includes modifying a marker to include a tether molecule and covalently binding the tether molecule to the peptide. The present invention also provides a labeled probe, comprising a peptide specific for a receptor and a marker. The marker is modified to include a tether molecule capable of covalently binding to the peptide. The peptide is typically derived from a bacteriophage or is a synthetic analog or derivative of the peptide. The receptor will typically be found on a surface of a bacterial cell. The method and probe of the invention are suitable for a rapid assay for a bacteria in a complex mixture.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
10/795,174
Filing Date
03/05/2004
Recommended Citation
Hicks, Clair D. and Crooks, Peter A., "Bioactive Peptide-Based Probes" (2010). Pharmaceutical Sciences Faculty Patents. 42.
https://uknowledge.uky.edu/ps_patents/42