US Patent Number
A conductive channel-containing membrane includes a membrane layer, and a SPPl connector polypeptide variant that is incorporated into the membrane layer to form an aperture through which conductance can occur when an electrical potential is applied across the membrane. A method of sensing a molecule, such as a polypeptide or nucleic acid molecule, makes use of the conductive channel- containing membrane. A method of DNA sequence makes use of the conductive channel-containing membrane.
University of Kentucky Research Foundation, Lexington, KY (US)
Guo, Peixuan and Wang, Shaoying, "Lipid Bilayer-Integrated SPP1 Connector Protein Nanopore and SPP1 Connector Protein Variants for Use as Lipid Bilayer-Integrated Nanopore" (2020). Pharmaceutical Sciences Faculty Patents. 194.