US Patent Number
10,772,940
Publication Date
9-15-2020
Abstract
The presently-disclosed subject matter includes isolated polypeptides that comprise a butyrylcholinestrase (BChE) polypeptide and a second polypeptide. The BChE polypeptide as well as the second polypeptide can be variants and/or fragments thereof. The presently-disclosed subject matter also includes a pharmaceutical composition that comprises the present isolated polypeptide and a suitable pharmaceutical carrier. Further still, methods are provided for treating cocaine-induced conditions, and comprise administering the isolated polypeptide and/or pharmaceutical compositions thereof to an individual.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
14/102,977
Filing Date
12-11-2013
Recommended Citation
Zhan, Chang-Guo; Zheng, Fang; Tai, Hsin-Hsiung; Chen, Xiabin; Xue, Liu; and Hou, Shurong, "Cocaine Hydrolase-Fc Fusion Proteins for Cocaine and Methods for Utilizing the Same" (2020). Pharmaceutical Sciences Faculty Patents. 192.
https://uknowledge.uky.edu/ps_patents/192
