US Patent Number
8653275
Publication Date
2-18-2014
Abstract
Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
12/300,197
Filing Date
05/11/2007
Recommended Citation
Crooks, Peter A.; Dwoskin, Linda P.; Zheng, Guangrong; Sumithran, Sangeetha; Allen, Davis D.; Zheng, Zhenfa; and Lockman, Paul, "Bis-Quaternary Ammonium Cyclophane Compounds that Interact with Neuronal Nicotinic Acetylcholine Receptors" (2014). Pharmaceutical Sciences Faculty Patents. 19.
https://uknowledge.uky.edu/ps_patents/19