US Patent Number
9,649,301
Publication Date
5-16-2017
Abstract
Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
14/829,527
Filing Date
8-18-2015
Recommended Citation
Crooks, Peter A.; Dwoskin, Linda P.; Zheng, Guangrong; Sumithran, Sangeetha; Allen, David; Zheng, Zhenfa; and Lockman, Paul, "Bis-Quaternary Ammonium Cyclophane Compounds that Interact with Neuronal Nicotinic Acetylcholine Receptors" (2017). Pharmaceutical Sciences Faculty Patents. 169.
https://uknowledge.uky.edu/ps_patents/169