US Patent Number
4383993
Publication Date
5-17-1983
Abstract
The invention relates to a novel method of administering the natural female sex hormones, 17 β-estradiol and progesterone, to achieve enhanced bioavailability thereof. The invention further relates to novel dosage forms of 17 β-estradiol and/or progesterone which are adapted for nasal administration, such as solutions, suspensions, gels and ointments. The dosage forms containing a combination of 17 β-estradiol and progesterone are particularly useful as contraceptives, while the dosage forms containing only one of the hormonal components find utility in the treatment of conditions such as menopause, menstrual disorders, etc., which are known to respond to administration of a natural or synthetic female hormone.
Assignees
University of Kentucky Research Foundation, Lexington, Ky.
Application Number
277,000
Filing Date
06/04/1981
Recommended Citation
Hussain, Anwar A.; Hirai, Shinichiro; and Bawarshi, Rima, "Nasal Dosage Forms Containing Natural Female Sex Horomones" (1983). Pharmaceutical Sciences Faculty Patents. 142.
https://uknowledge.uky.edu/ps_patents/142
