US Patent Number
4267449
Publication Date
5-12-1981
Abstract
A method for detecting leaky ampules filled with a liquid such as a parenteral solution. The ampules to be tested are immersed in a solution containing a short-lived radionuclide, and a pressure differential is imposed between the solution containing the radionuclide and the parenteral solution or other liquid contained in the ampules. The ampules are then removed from solution, decontaminated to remove any solution adhering to the outer surface and pores thereof, dried, and finally examined for electromagnetic radiation, preferably gamma radiation, emanating from the interior of the ampules which would indicate a leaky condition thereof.
Assignees
University of Kentucky Research Foundation, Lexington, Ky.
Application Number
66,390
Filing Date
08/14/1979
Recommended Citation
DeLuca, Patrick P. and Butler, L. David, "Testing the Integrity of Liquid Containing Hermetically Sealed Containers by the Use of Radioactive Markers" (1981). Pharmaceutical Sciences Faculty Patents. 130.
https://uknowledge.uky.edu/ps_patents/130
