US Patent Number
7425319
Publication Date
9-16-2008
Abstract
The present invention is directed to methods of using pro-NAD agents capable of enhancing the dermal and epidermal skin cell NAD content. These pro-NAD agents may be administered topically, orally, or parenterally to enhance DNA repair and other protective responses to DNA damage. The invention further relates to pharmaceutical compositions comprising pro-NAD agents that effectively elevate intracellular NAD content. Finally, the invention relates to the method of using the pro-NAD agents to treat disorders such as sunburn and other skin deterioration that results from DNA damage in skin cells.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
10/256,403
Filing Date
09/27/2002
Recommended Citation
Jacobson, Elaine L. and Jacobson, Myron K., "Method for Enhancing Protective Cellular Responses to Genotoxic Stress in Skin" (2008). Pharmaceutical Sciences Faculty Patents. 118.
https://uknowledge.uky.edu/ps_patents/118