Archived
This content is available here strictly for research, reference, and/or recordkeeping and as such it may not be fully accessible. If you work or study at University of Kentucky and would like to request an accessible version, please use the SensusAccess Document Converter.
US Patent Number
6074674
Publication Date
6-13-2000
Abstract
The present invention provides, inter alia, formulations useful to ameliorate symptoms associated with mucosal abrasions, specifically those due to dental orthodontic brackets; oral surgery; periodontal surgery or other procedures. For instance, there is a formulation comprising: 65 to 75% microcrystalline wax; 5 to 15% non-ionic polymer; 15 to 25% topical anesthetic; and 1 to 5% surfactant, wherein the ratio of non-ionic polymer to microcrystalline wax is no greater than 0.2. Preferably, for solid topical anesthetics, the particle size is less than the apertures of a 100-mesh screen. However, the topical anesthetic may also be a liquid. Formulations wherein the mixture is a homogeneous matrix is preferred.
Assignees
University of Kentucky Research Foundation, Lexington, Ky.
Application Number
09/119,099
Filing Date
07/20/1998
Recommended Citation
Jay, Michael Joseph; Kluemper, G. Thomas; and Kim, Sang Hun, "Formulations for Sustained-Release of Topical Anesthetics and Methods of Making and Using Same" (2000). Pharmaceutical Sciences Faculty Patents. 108.
https://uknowledge.uky.edu/ps_patents/108
