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Abstract
Positive-stranded RNA (+RNA) viruses exploit host cell machinery by subverting host proteins and membranes and altering cellular pathways during infection. To achieve robust replication, some +RNA viruses, such as poliovirus (PV), build special intracellular compartments, called viral replication organelles. A recent work from the Altan-Bonnett laboratory [1] gave new insights into the formation of poliovirus replication organelles, which are unique subcellular structures containing many individual replication complexes as a result of dynamic cellular membrane remodeling.
Document Type
Commentary
Publication Date
11-5-2010
Digital Object Identifier (DOI)
http://dx.doi.org/10.3390/v2112436
Repository Citation
Sasvari, Zsuzsanna and Nagy, Peter D., "Making of Viral Replication Organelles by Remodeling Interior Membranes" (2010). Plant Pathology Faculty Publications. 28.
https://uknowledge.uky.edu/plantpath_facpub/28
Notes/Citation Information
Published in Viruses, v. 2, no. 11, p. 2436-2442.
© 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.