Abstract
Babesiosis, a common disease of animals, can infect humans via vector "tick bite", particularly in endemic areas. The recent reports of fatal cases in Hepatitis C and postliver transplant patients resulting from transfusion of contaminated blood should alert the medical profession regarding this emerging dilemma in endemic as well as nonendemic areas and the need for accurate blood screening for transfusion. Here, we illustrate different stages of the parasite lifecycle, progression of babesiosis in animal model, some aspects of pathologic outcomes, ongoing therapeutic modalities, and a feasible Acridine Orange fluorescent methodology for the diagnostic evaluation of blood samples.
Document Type
Review
Publication Date
2012
Digital Object Identifier (DOI)
http://dx.doi.org/10.1155/2012/431761
Repository Citation
Oz, Helieh S. and Westlund, Karin N., ""Human Babesiosis": An Emerging Transfusion Dilemma" (2012). Physiology Faculty Publications. 49.
https://uknowledge.uky.edu/physiology_facpub/49
Notes/Citation Information
Published in International Journal of Hepatology, v. 2012, article ID 431761, p. 1-5.
Copyright © 2012 Helieh S. Oz and Karin H. Westlund. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.