This collection was formerly known as Molecular and Biomedical Pharmacology Faculty Publications. It absorbed Graduate Center for Nutritional Sciences Faculty Publications and became Pharmacology and Nutritional Sciences Faculty Publications in early 2014.

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Submissions from 2017

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Inhibition of Cholesterol Biosynthesis Through RNF145-Dependent Ubiquitination of SCAP, Li Zhang, Prashant Rajbhandari, Christina Priest, Jaspreet Sandhu, Xiaohui Wu, Ryan E. Temel, Antonio Castrillo, Thomas Q. de Aguiar Vallim, Tamer Sallam, and Peter Tontonoz

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Hydroxyurea Differentially Modulates Activator and Repressors of γ-globin Gene in Erythroblasts of Responsive and Non-Responsive Patients with Sickle Cell Disease in Correlation with Index of Hydroxyurea Responsiveness, Xingguo Zhu, Tianxiang Hu, Meng Hsuan Ho, Yongchao Wang, Miao Yu, Niren Patel, Wenhu Pi, Jeong-Hyeon Choi, Hongyan Xu, Vadivel Ganapathy, Ferdane Kutlar, Abdullah Kutlar, and Dorothy Tuan

Submissions from 2016

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Resveratrol Supplementation Confers Neuroprotection in Cortical Brain Tissue of Nonhuman Primates Fed a High-Fat/Sucrose Diet, Michel Bernier, Devin Wahl, Ahmed Ali, Joanne Allard, Shakeela Faulkner, Artur Wnorowski, Mitesh Sanghvi, Ruin Moaddel, Irene Alfaras, Julie A. Mattison, Stefano Tarantini, Zsuzsanna Tucsek, Zoltan Ungvari, Anna Csiszar, Kevin J. Pearson, and Rafael de Cabo

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TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions, Xiaofeng Chen, Debra L. Rateri, Deborah A. Howatt, Anju Balakrishnan, Jessica J. Moorleghen, Lisa A. Cassis, and Alan Daugherty

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Current and Emerging Uses of Statins in Clinical Therapeutics: A Review, Jonathan T. Davies, Spencer F. Delfino, Chad E. Feinberg, Meghan F. Johnson, Veronica L. Nappi, Joshua T. Olinger, Anthony P. Schwab, and Hollie I. Swanson

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Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury, Jennifer L. Furman, Pradoldej Sompol, Susan D. Kraner, Melanie M. Pleiss, Esther J. Putman, Jacob Dunkerson, Hafiz Mohmmad Abdul, Kelly N. Roberts, Stephen William Scheff, and Christopher M. Norris

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Red-Shifted Aequorin Variants Incorporating Non-Canonical Amino Acids: Applications in In Vivo Imaging, Kristen M. Grinstead, Laura Rowe, Mark Ensor, Smita Joel, Pirouz Daftarian, Emre Dikici, Jean-Marc Zingg, and Sylvia Daunert

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Serum Amyloid A Impairs the Antiinflammatory Properties of HDL, Chang Yeop Han, Chongren Tang, Myriam E. Guevara, Hao Wei, Tomasz Wietecha, Baohai Shao, Savitha Subramanian, Mohamed Omer, Shari Wang, Kevin D. O'Brien, Santica M. Marcovina, Thomas N. Wight, Tomas Vaisar, Maria C. de Beer, Frederick C. de Beer, William R. Osborne, Keith B. Elkon, and Alan Chait

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Aβ40 Reduces P-Glycoprotein at the Blood-Brain Barrier Through the Ubiquitin-Proteasome Pathway, Anika M. S. Hartz, Yu Zhong, Andrea Wolf, Harry LeVine III, David S. Miller, and Björn Bauer

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Melanocortin 1 Receptor: Structure, Function, and Regulation, Erin M. Wolf Horrell, Mary C. Boulanger, and John A. D'Orazio

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Network-Driven Plasma Proteomics Expose Molecular Changes in the Alzheimer's Brain, Philipp A. Jaeger, Kurt M. Lucin, Markus Britschgi, Badri Vardarajan, Ruo-Pan Huang, Elizabeth D. Kirby, Rachelle Abbey, Bradley F. Boeve, Adam L. Boxer, Lindsay A. Farrer, NiCole Finch, Neill R. Graff-Radford, Elizabeth Head, Matan Hofree, Ruochun Huang, Hudson Johns, Anna Karydas, David S. Knopman, Andrey Loboda, Eliezer Masliah, Ramya Narasimhan, Ronald C. Petersen, Alexei Podtelezhnikov, Suraj Pradhan, Rosa Rademakers, Chung-Huan Sun, Steven G. Younkin, Bruce L. Miller, Trey Ideker, and Tony Wyss-Coray

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p70S6K1 (S6K1)-Mediated Phosphorylation Regulates Phosphatidylinositol 4-Phosphate 5-Kinase Type I γ Degradation and Cell Invasion, Naser Jafari, Qiaodan Zheng, Liqing Li, Wei Li, Lei Qi, Jianyong Xiao, Tianyan Gao, and Cai Huang

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Steroid Binding to Autotaxin Links Bile Salts and Lysophosphatidic Acid Signalling, Willem-Jan Keune, Jens Hausmann, Ruth Bolier, Dagmar Tolenaars, Andreas Kremer, Tatjana Heidebrecht, Robbie P. Joosten, Manjula Sunkara, Andrew J. Morris, Elisa Matas-Rico, Wouter H. Moolenaar, Ronald P. Oude Elferink, and Anastassis Perrakis

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Impact of Individual Acute Phase Serum Amyloid A Isoforms on HDL Metabolism in Mice, Myung-Hee Kim, Maria C. de Beer, Joanne M. Wroblewski, Richard J. Charnigo, Ailing Ji, Nancy R. Webb, Frederick C. de Beer, and Deneys R. van der Westhuyzen

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mTOR: Alzheimer's Disease Prevention for APOE4 Carriers, Ai-Ling Lin, D. Allan Butterfield, and Arlan Richardson

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1H-MRS Metabolites in Adults with Down Syndrome: Effects of Dementia, Ai-Ling Lin, David Powell, Allison Caban-Holt, Gregory A. Jicha, William C. Robertson, Brian T. Gold, Roberta Davis, Erin L. Abner, Donna M. Wilcock, Frederick A. Schmitt, and Elizabeth Head

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Structure and Functions of Angiotensinogen, Hong Lu, Lisa A. Cassis, Craig W. Vander Kooi, and Alan Daugherty

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Thrombospondin 1 Deficiency Ameliorates the Development of Adriamycin-Induced Proteinuric Kidney Disease, Hasiyeti Maimaitiyiming, Qi Zhou, and Shuxia Wang

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Caloric Restriction Preserves Memory and Reduces Anxiety of Aging Mice with Early Enhancement of Neurovascular Functions, Ishita Parikh, Janet Guo, Kai-Hsiang Chuang, Yu Zhong, Ralf G. Rempe, Jared D. Hoffman, Rachel Armstrong, Björn Bauer, Anika M. S. Hartz, and Ai-Ling Lin

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The TNFα-Transgenic Rat: Hippocampal Synaptic Integrity, Cognition, Function, and Post-Ischemic Cell Loss, L. Creed Pettigrew, Richard J. Kryscio, and Christopher M. Norris

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Talin2-Mediated Traction Force Drives Matrix Degradation and Cell Invasion, Lei Qi, Naser Jafari, Xiang Li, Zaozao Chen, Liqing Li, Vesa P. Hytönen, Benjamin T. Goult, Chang-Guo Zhan, and Cai Huang

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Binge Ethanol Exposure Causes Endoplasmic Reticulum Stress, Oxidative Stress and Tissue Injury in the Pancreas, Zhenhua Ren, Xin Wang, Mei Xu, Fanmuyi Yang, Jacqueline A. Frank, Zun-Ji Ke, and Jia Luo

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Integrated Molecular Pathway Analysis Informs a Synergistic Combination Therapy Targeting PTEN/PI3K and EGFR Pathways for Basal-Like Breast Cancer, Qing-Bai She, Sofia K. Gruvberger-Saal, Matthew Maurer, Yilun Chen, Mervi Jumppanen, Tao Su, Meaghan Dendy, Ying-Ka Ingar Lau, Lorenzo Memeo, Hugo M. Horlings, Marc J. van de Vijver, Jorma Isola, Hanina Hibshoosh, Neal Rosen, Ramon Parsons, and Lao H. Saal

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Development of a Course-Based Undergraduate Research Experience to Introduce Drug-Receptor Concepts, Hollie I. Swanson, Ok-Kyong Park-Sarge, Thushani Rodrigo-Peiris, Lin Xiang, and Vincent M. Cassone

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TGF-β Signaling: New Insights Into Aortic Aneurysms, Sean E. Thatcher