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Submissions from 2020

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Nlrp3 Inflammasome Signaling Regulates the Homing and Engraftment of Hematopoietic Stem Cells (HSPCs) by Enhancing Incorporation of CXCR4 Receptor into Membrane Lipid Rafts, Mateusz Adamiak, Ahmed K. Abdel-Latif, Kamila Bujko, Arjun Thapa, Krzysztof Anusz, Michał Tracz, Katarzyna Brzezniakiewicz-Janus, Janina Ratajczak, Magda Kucia, and Mariusz Z Ratajczak

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Liposomal Delivery of Azithromycin Enhances Its Immunotherapeutic Efficacy and Reduces Toxicity in Myocardial Infarction, Ahmed Al-Darraji, Renée R. Donahue, Himi Tripathi, Hsuan Peng, Bryana M. Levitan, Lakshman Chelvarajan, Dalia Haydar, Erhe Gao, David Henson, John C. Gensel, David J. Feola, Vincent J. Venditto, and Ahmed K. Abdel-Latif

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Uremia Preventing Osmotic Demyelination Syndrome Despite Rapid Hyponatremia Correction, Srinadh Annangi, Snigdha Nutalapati, Srikanth Naramala, Pradeep Yarra, and Khalid Bashir

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Heart Failure in Humans Reduces Contractile Force in Myocardium from Both Ventricles, Cheavar A. Blair, Elizabeth A Brundage, Katherine L. Thompson, Arnold J. Stromberg, Maya Guglin, Brandon J Biesiadecki, and Kenneth S. Campbell

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Gynecologic Large Cell Neuroendocrine Carcinoma: A Review, Grant Burkeen, Aman Chauhan, Rohitashva Agrawal, Riva Raiker, Jill M. Kolesar, Lowell B. Anthony, B. Mark Evers, and Susanne Arnold

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Circadian Disruption with Constant Light Exposure Exacerbates Atherosclerosis in Male ApolipoproteinE-Deficient Mice, Jeffrey M. Chalfant, Deborah A. Howatt, Lisa R. Tannock, Alan Daugherty, and Julie S. Pendergast

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Hereditary Hypophosphatemic Rickets with Hypercalciuria (HHRH) Presenting with Genu Valgum Deformity: Treatment with Phosphate Supplementation and Surgical Correction, Juan M. Colazo, Seth A. Reasoner, Ginger Holt, Marie-Claude M. Faugere, and Kathryn M. Dahir

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Clinical Application of Oncolytic Viruses: A Systematic Review, Mary Cook and Aman Chauhan

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Low Yield of Thyroid-Function Tests in Adult Hospitalized Patients -- A Retrospective Analysis, Prerna Dogra, Robin Paudel, Sujata Panthi, Evan Cassity, and Lisa R. Tannock

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Spermine Synthase and MYC Cooperate to Maintain Colorectal Cancer Cell Survival by Repressing Bim Expression, Yubin Guo, Qing Ye, Pan Deng, Yanan Cao, Daheng He, Zhaohe Zhou, Chi Wang, Yekaterina Y. Zaytseva, Charles E. Schwartz, Eun Young Lee, B. Mark Evers, Andrew J. Morris, Side Liu, and Qing-Bai She

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Immune-Mediated Genetic Pathways Resulting in Pulmonary Function Impairment Increase Lung Cancer Susceptibility, Linda Kachuri, Mattias Johansson, Sara R. Rashkin, Rebecca E. Graff, Yohan Bossé, Venkata Manem, Neil E. Caporaso, Maria Teresa Landi, David C. Christiani, Paolo Vineis, Geoffrey Liu, Ghislaine Scelo, David Zaridze, Sanjay S Shete, Demetrius Albanes, Melinda C. Aldrich, Adonina Tardón, Gad Rennert, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, Heike Bickeböller, John K. Field, Michael P Davies, M. Dawn Teare, Lambertus A. Kiemeney, Stig E. Bojesen, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Loïc Le Marchand, Iona Cheng, Matthew B. Schabath, Eric J. Duell, Angeline S. Andrew, Jonas Manjer, Philip Lazarus, Susanne M. Arnold, James D. McKay, Nima C. Emami, Matthew T. Warkentin, Yonathan Brhane, Ma'en Obeidat, Richard M. Martin, Caroline Relton, George Davey Smith, Philip C. Haycock, Christopher I. Amos, Paul Brennan, John S. Witte, and Rayjean J. Hung

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EGFR Testing and Erlotinib Use in Non-Small Cell Lung Cancer Patients in Kentucky, Kara L. Larson, Bin Huang, Quan Chen, Thomas C. Tucker, Marissa Schuh, Susanne M. Arnold, and Jill M. Kolesar

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Genome-Wide DNA Methylation Profiling in Human Breast Tissue by Illumina TruSeq Methyl Capture EPIC Sequencing and Infinium MethylationEPIC Beadchip Microarray, Nan Lin, Jinpeng Liu, James Castle, Jun Wan, Aditi Shendre, Yunlong Liu, Chi Wang, and Chunyan He

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Safety, Feasibility, and Efficacy of Early Rehabilitation in Patients Requiring Continuous Renal Replacement: A Quality Improvement Study, Kirby P. Mayer, Amanda R. Hornsby, Victor Ortiz Soriano, Timothy C. Lin, Jennifer T. Cunningham, Hanwen Yuan, Caroline E. Hauschild, Peter E. Morris, and Javier A. Neyra

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Recovery from COVID-19 and Acute Respiratory Distress Syndrome: The Potential Role of an Intensive Care Unit Recovery Clinic: A Case Report, Kirby P. Mayer, Jamie L. Sturgill, Anna G. Kalema, Melissa K. Soper, Sherif M. Seif, Evan P. Cassity, Jimmi Hatton Kolpek, Esther E. Dupont-Versteegden, Ashley A. Montgomery-Yates, and Peter E. Morris

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Acute Skeletal Muscle Wasting and Dysfunction Predict Physical Disability at Hospital Discharge in Patients with Critical Illness, Kirby P. Mayer, Melissa L. Thompson Bastin, Ashley A. Montgomery-Yates, Amy M. Pastva, Esther E. Dupont-Versteegden, Selina M. Parry, and Peter E. Morris

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Regulation of Myofilament Contractile Function in Human Donor and Failing Hearts, Kerry S. McDonald, Laurin M. Hanft, Joel C. Robinett, Maya Guglin, and Kenneth S. Campbell

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Evaluating the Effectiveness of Undergraduate Clinical Education Programs, John W. Ragsdale, Andrea Berry, Jennifer W. Gibson, Christiane R. Herber-Valdez, Lauren J. Germain, and Deborah L. Engle

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Development, Implementation and Outcomes of a Quality Assurance System for the Provision of Continuous Renal Replacement Therapy in the Intensive Care Unit, Eloy F. Ruiz, Victor M. Ortiz-Soriano, Monica Talbott, Bryan A. Klein, Melissa L. Thompson Bastin, Kirby P. Mayer, Emily B. Price, Robert Dorfman, Brandi N. Adams, Lisa J. Fryman, Javier A. Neyra, and The University of Kentucky CRRT Quality Assurance Group

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A Qualitative Exploration to Understand Hospitalists’ Attitude toward the Patient Experience Scoring System, Ankur Segon, Yogita Segon, Vivek Kumar, and Hirotaka Kato

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Risk Factors for and Prediction of Post-Intubation Hypotension in Critically Ill Adults: A Multicenter Prospective Cohort Study, Nathan J. Smischney, Rahul Kashyap, Ashish K. Khanna, Ernesto Brauer, Lee E. Morrow, Mohamed O. Seisa, Darrell R. Schroeder, Daniel A. Diedrich, Ashley Montgomery, Pablo Moreno Franco, Uchenna R. Ofoma, David A. Kaufman, Ayan Sen, Cynthia Callahan, Chakradhar Venkata, Gozde Demiralp, Rudy Tedja, Sarah Lee, Mariya Geube, Santhi I. Kumar, Peter E. Morris, Vikas Bansal, Salim Surani, and On behalf of SCCM Discovery (Critical Care Research Network of Critical Care Medicine) HEMAIR Investigators Consortium

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Combating Acquired Resistance to MAPK Inhibitors in Melanoma by Targeting Abl1/2-Mediated Reactivation of MEK/ERK/MYC Signaling, Rakshamani Tripathi, Zulong Liu, Aditi Jain, Anastasia Lyon, Christina Meeks, Dana Richards, Jinpeng Liu, Daheng He, Chi Wang, Marika Nespi, Andrey Rymar, Peng Wang, Melissa Wilson, and Rina Plattner

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Impact of the Affordable Care Act on Referral to Care for People Living with HIV in Appalachia, Cameron A. Wade, Timothy N. Crawford, Nicole Leedy, and Alice C. Thornton

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MicroRNA-148a Regulates Low-Density Lipoprotein Metabolism by Repressing the (Pro)renin Receptor, Na Wang, Lishu He, Hui Lin, Lunbo Tan, Yuan Sun, Xiaoying Zhang, A. H. Jan Danser, Hong S. Lu, Yongcheng He, and Xifeng Lu

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Healthcare Reform in the U.S. Must Be Driven by Policy and Data, Not Politics and Idealogy, Teresa M. Waters and Michael Karpf