Date Available
12-15-2024
Year of Publication
2024
Document Type
Master's Thesis
Degree Name
Master of Science in Nutrition and Food Systems (MSNFS)
College
Agriculture, Food and Environment
Department/School/Program
Dietetics and Human Nutrition
Advisor
Dr Robin Shoemaker
Co-Director of Graduate Studies
Dr Dawn Brewer
Abstract
Background: Hypertensive disorders of pregnancy (HDP) represent a significant public health issue, contributing to maternal and fetal morbidity and mortality. Women from lower socioeconomic backgrounds or marginalized racial and ethnic groups face higher risks of HDP, which have been incompletely described. In addition, risk for HDP may be linked to a reduction in the normal activity of the renin-angiotensin-aldosterone system (RAAS). This study investigates the role of socioeconomic factors and RAAS components in the risk for HDP and adverse maternal and neonatal outcomes. Methods: This study is a secondary analysis of data from 180 pregnant individuals from a high-risk maternal-fetal medicine clinic. Clinical data was collected during pregnancy and serum RAAS biomarkers from the first trimester were quantified in serum via liquid chromatography with tandem mass spectrometry. Participants were grouped by insurance status (Analysis 1 – Medicaid vs. private insurance) and race/ethnicity (Analysis 2). Clinical characteristics and maternal and neonatal outcomes were analyzed using chi-square tests for categorical variables and t-tests for continuous variables. Results: Medicaid patients had higher rates of chronic hypertension and obesity with a P value of P
Digital Object Identifier (DOI)
https://doi.org/10.13023/etd.2024.496
Funding Information
Fulbright Scholarship
Recommended Citation
Ndashaala, Esther Letushila, "Role of social determinants of health and the renin- angiotensin aldosterone system in risk for hypertensive disorders of pregnancy and related adverse outcomes." (2024). Theses and Dissertations--Nutrition and Food Systems. 105.
https://uknowledge.uky.edu/foodsci_etds/105
Included in
Community Health Commons, Community Health and Preventive Medicine Commons, Dietetics and Clinical Nutrition Commons, Environmental Public Health Commons, Health and Medical Administration Commons, Health Information Technology Commons, Health Services Administration Commons, Health Services Research Commons, Maternal and Child Health Commons, Medical Nutrition Commons, Patient Safety Commons, Public Health Education and Promotion Commons, Women's Health Commons
