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Submissions from 2021

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Epigenome-Wide Association Study of Kidney Function Identifies Trans-Ethnic and Ethnic-Specific Loci, Charles E. Breeze; Anna Batorsky; Mi Kyeong Lee; Mindy D. Szeto; Xiaoguang Xu; Daniel L. McCartney; Rong Jiang; Amit Patki; Holly J. Kramer; James M. Eales; Laura Raffield; Leslie Lange; Ethan Lange; Peter Durda; Yongmei Liu; Russ P. Tracy; David Van Den Berg; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed MESA Multi-Omics Working Group; Kathryn L. Evans; William E. Kraus; and Donna K. Arnett

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Persistent Disparities in Smoking among Rural Appalachians: Evidence from the Mountain Air Project, Kathryn Cardarelli, Susan C. Westneat, Madeline Dunfee, Beverly May, Nancy Schoenberg, and Steven R. Browning

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Vitamin D Supplementation among Bangladeshi Children under-Five Years of Age Hospitalised for Severe Pneumonia: A Randomised Placebo Controlled Trial, Fahmida Chowdhury, Abu Sadat Mohammad Sayeem Bin Shahid, Mosharrat Tabassum, Irin Parvin, Probir Kumar Ghosh, Mohammad Iqbal Hossain, Nur Haque Alam, A. S. G. Faruque, Sayeeda Huq, Lubaba Shahrin, Nusrat Homaira, Zakiul Hassan, Zubair Akhtar, S. Mah-E-Muneer, George J. Fuchs III, Tahmeed Ahmed, and Mohammod Jobayer Chisti

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Exploring COVID-19 Case Fatality in Relation to the Prevalence of Chronic Conditions and Health Behaviors in Appalachian Kentucky, W. Jay Christian

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Estimating the Population Attributable Fraction of Asthma Due to Electronic Cigarette Use and Other Risk Factors Using Kentucky Behavioral Risk Factor Survey Data, 2016-2017, W. Jay Christian and Courtney J. Walker

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Protecting P-Glycoprotein at the Blood-Brain Barrier from Degradation in an Alzheimer's Disease Mouse Model, Yujie Ding, Yu Zhong, Andrea Baldeshwiler, Erin L. Abner, Björn Bauer, and Anika M. S. Hartz

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Case Report: The Complexities of Managing Medications and the Importance of Deprescribing Anticholinergics in Older Adults, Taylor Elliott, Lynne Eckmann, and Daniela C. Moga

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Impact of the COVID-19 Shutdown on Mental Health in Appalachia by Working Status, Erin N. Haynes, Timothy J. Hilbert, Susan C. Westneat, Kate Leger, Katie Keynton, and Heather M. Bush

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Factors that Influence Enrollment in Syringe Services Programs in Rural Areas: A Qualitative Study among Program Clients in Appalachian Kentucky, Umedjon Ibragimov, Katherine E. Cooper, Evan Batty, April M. Ballard, Monica Fadanelli, Skylar B. Gross, Emma M. Klein, Scott Lockard, April M. Young, and Hannah L. F. Cooper

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Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify MYRIP, TRAPPC11, and SLC27A6 of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population, Marguerite R. Irvin, Praful Aggarwal, Steven A. Claas, Lisa de Las Fuentes, Anh N. Do, C. Charles Gu, Andrea Matter, Benjamin S. Olson, Amit Patki, Karen Schwander, Joshua D. Smith, Vinodh Srinivasasainagendra, Hemant K. Tiwari, Amy J. Turner, Deborah A. Nickerson, Dabeeru C. Rao, Ulrich Broeckel, and Donna K. Arnett

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Memory-Related Frontal Brainwaves Predict Transition to Mild Cognitive Impairment in Healthy Older Individuals Five Years before Diagnosis, Yang Jiang, Juan Li, Frederick A. Schmitt, Gregory A. Jicha, Nancy B. Munro, Xiaopeng Zhao, Charles D. Smith, Richard J. Kryscio, and Erin L. Abner

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The Association of Circulating Amylin with β-Amyloid in Familial Alzheimer's Disease, Han Gia Ly, Nirmal Verma, Savita Sharma, Deepak Kotiya, Sanda Despa, Erin L. Abner, Peter T. Nelson, Gregory A. Jicha, Donna M. Wilcock, Larry B. Goldstein, Rita Guerreiro, José Brás, Angela J. Hanson, Suzanne Craft, Andrew J. Murray, Geert Jan Biessels, Claire Troakes, Henrik Zetterberg, John Hardy, Tammaryn Lashley, Alzheimer’s disease Exome Sequencing Group, and Florin Despa

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Sex, Diabetes Status and Cognition: Findings from the Study of Longevity in Diabetes, Chris Moran, Paola Gilsanz, Michal S. Beeri, Rachel A. Whitmer, and Mary E. Lacy

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Chromosome Xq23 Is Associated with Lower Atherogenic Lipid Concentrations and Favorable Cardiometabolic Indices, Pradeep Natarajan, Akhil Pampana, Sarah E. Graham, Sanni E. Ruotsalainen, James A. Perry, Paul S. de Vries, Jai G. Broome, James P. Pirruccello, Michael C. Honigberg, Krishna Aragam, Brooke Wolford, Jennifer A. Brody, Lucinda Antonacci-Fulton, Moscati Arden, Stella Aslibekyan, Themistocles L. Assimes, Christie M. Ballantyne, Lawrence F. Bielak, Joshua C. Bis, Brian E. Cade, and Donna K. Arnett

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An Experimental Education Project for Consultations of Older Adults during the Pandemic and Healthcare Lockdown, Agnieszka Neumann-Podczaska, Mikołaj Seostianin, Konrad Madejczyk, Piotr Merks, Urszula Religioni, Zofia Tomczak, Sławomir Tobis, Daniela C. Moga, Melody Ryan, and Katarzyna Wieczorowska-Tobis

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Predictors of Chronic Opioid Therapy in Medicaid Beneficiaries with HIV Who Initiated Antiretroviral Therapy, GYeon Oh, Emily S. Brouwer, Erin L. Abner, David W. Fardo, Patricia R. Freeman, Chris Delcher, and Daniela C. Moga

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Aberrant AZIN2 and Polyamine Metabolism Precipitates Tau Neuropathology, Leslie A. Sandusky-Beltran, Andrii Kovalenko, Devon S. Placides, Kevin Ratnasamy, Chao Ma, Jerry B. Hunt, Huimin Liang, John Ivan T. Calahatian, Camilla Michalski, Margaret Fahnestock, Laura J. Blair, April L. Darling, Jeremy D. Baker, Sarah N. Fontaine, Chad A. Dickey, Joshua J. Gamsby, Kevin R. Nash, Erin L. Abner, Maj-Linda B. Selenica, and Daniel C. Lee

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Identification of Novel and Rare Variants Associated with Handgrip Strength Using Whole Genome Sequence Data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program, Chloé Sarnowski, Han Chen, Mary L. Biggs, Sylvia Wassertheil-Smoller, Jan Bressler, Marguerite R. Irvin, Kathleen A. Ryan, David Karasik, Donna K. Arnett, L. Adrienne Cupples, David W. Fardo, Stephanie M. Gogarten, Benjamin D. Heavner, Deepti Jain, Hyun Min Kang, Charles Kooperberg, Arch G. Mainous, Braxton D. Mitchell, Alanna C. Morrison, and Jeffrey R. O'Connell

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Age and Sex Are Associated with the Plasma Lipidome: Findings from the GOLDN Study, Emily Slade, Marguerite R. Irvin, Kevin Xie, Donna K. Arnett, Steven A. Claas, Tobias Kind, David W. Fardo, and Gregory A. Graf

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Novel Influences of Sex and APOE Genotype on Spinal Plasticity and Recovery of Function after Spinal Cord Injury, Lydia E. Strattan, Daimen R. Britsch, Chris M. Calulot, Rachel S. J. Maggard, Erin L. Abner, Lance A. Johnson, and Warren J. Alilain

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Serological Survey of Leptospira Infection in Arabian Horses in Poland, Bernard Wasiński, Katarzyna Paschalis-Trela, Jan Trela, Michał Czopowicz, Jerzy Kita, Monika Żychska, Anna Cywińska, Iwona Markowska-Daniel, Craig N. Carter, and Lucjan Witkowski

Submissions from 2020

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Evidence of Nickel and Other Trace Elements and Their Relationship to Clinical Findings in Acute Mesoamerican Nephropathy: A Case-Control Analysis, Rebecca S. B. Fischer, Jason M. Unrine, Chandan Vangala, Wayne T. Sanderson, Sreedhar Mandayam, and Kristy O. Murray

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Appalachian Environmental Health Literacy: Building Knowledge and Skills to Protect Health, Anna G. Hoover, Annie Koempel, W. Jay Christian, Kimberly I. Tumlin, Kelly G. Pennell, Steven Evans, Malissa McAlister, Lindell E. Ormsbee, and Dawn Brewer

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Distinct Clinicopathologic Clusters of Persons with TDP-43 Proteinopathy, Yuriko Katsumata, Erin L. Abner, Shama Karanth, Merilee A. Teylan, Charles N. Mock, Matthew D. Cykowski, Edward B. Lee, Kevin L. Boehme, Shubhabrata Mukherjee, John S. K. Kauwe, Richard J. Kryscio, Frederick A. Schmitt, David W. Fardo, and Peter T. Nelson

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EGFR Testing and Erlotinib Use in Non-Small Cell Lung Cancer Patients in Kentucky, Kara L. Larson, Bin Huang, Quan Chen, Thomas C. Tucker, Marissa Schuh, Susanne M. Arnold, and Jill M. Kolesar